5lbm - Revision history

OCA at 16:14, 4 October 2023

2023-10-04T16:14:03Z

←Older revision		Revision as of 16:14, 4 October 2023
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	<StructureSection load='5lbm' size='340' side='right'caption='[[5lbm]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='5lbm' size='340' side='right'caption='[[5lbm]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lbm]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Eco57 Eco57~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5LBM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lbm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LBM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">frmR, Z0457, ECs0412 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbm OCA], [https://pdbe.org/5lbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lbm RCSB], [https://www.ebi.ac.uk/pdbsum/5lbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbm ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5lbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbm OCA], [~~http~~://pdbe.org/5lbm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5lbm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5lbm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbm ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FRMR_ECO57 FRMR_ECO57]] Repressor of the frmRAB operon.	+	[https://www.uniprot.org/uniprot/FRMR_ECO57 FRMR_ECO57] Repressor of the frmRAB operon.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Eco57~~]]	+	[[Category: Escherichia coli O157:H7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baker~~, P J~~]]	+	[[Category: Baker PJ]]
-	[[Category: Bisson, C]]	+	[[Category: Bisson C]]
-	[[Category: Chivers~~, P T~~]]	+	[[Category: Chivers PT]]
-	[[Category: Green, J]]	+	[[Category: Green J]]
-	~~[[Category: Csor/rcnr escherichia coli frmr methylene bridge]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 07:06, 5 August 2020

2020-08-05T07:06:17Z

←Older revision		Revision as of 07:06, 5 August 2020
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	==The asymmetric tetrameric structure of the formaldehyde sensing transcriptional repressor FrmR from Escherichia coli==		==The asymmetric tetrameric structure of the formaldehyde sensing transcriptional repressor FrmR from Escherichia coli==
-	<StructureSection load='5lbm' size='340' side='right' caption='[[5lbm]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='5lbm' size='340' side='right'caption='[[5lbm]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5lbm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5LBM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5lbm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LBM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5lbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbm OCA], [http://pdbe.org/5lbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lbm RCSB], [http://www.ebi.ac.uk/pdbsum/5lbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbm ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">frmR, Z0457, ECs0412 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbm OCA], [http://pdbe.org/5lbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lbm RCSB], [http://www.ebi.ac.uk/pdbsum/5lbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Eco57]]
		+	[[Category: Large Structures]]
	[[Category: Baker, P J]]		[[Category: Baker, P J]]
	[[Category: Bisson, C]]		[[Category: Bisson, C]]

OCA at 21:32, 22 December 2016

2016-12-22T21:32:14Z

←Older revision		Revision as of 21:32, 22 December 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 5lbm is ~~ON HOLD until Paper~~ Publication	+	==The asymmetric tetrameric structure of the formaldehyde sensing transcriptional repressor FrmR from Escherichia coli==
		+	<StructureSection load='5lbm' size='340' side='right' caption='[[5lbm]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5lbm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbm OCA], [http://pdbe.org/5lbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lbm RCSB], [http://www.ebi.ac.uk/pdbsum/5lbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbm ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FRMR_ECO57 FRMR_ECO57]] Repressor of the frmRAB operon.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Most organisms are exposed to the genotoxic chemical formaldehyde, either from endogenous or environmental sources. Therefore, biology has evolved systems to perceive and detoxify formaldehyde. The frmRA(B) operon that is present in many bacteria represents one such system. The FrmR protein is a transcriptional repressor that is specifically inactivated in the presence of formaldehyde, permitting expression of the formaldehyde detoxification machinery (FrmA and FrmB, when the latter is present). The X-ray structure of the formaldehyde-treated Escherichia coli FrmR (EcFrmR) protein reveals the formation of methylene bridges that link adjacent Pro2 and Cys35 residues in the EcFrmR tetramer. Methylene bridge formation has profound effects on the pattern of surface charge of EcFrmR and combined with biochemical/biophysical data suggests a mechanistic model for formaldehyde-sensing and derepression of frmRA(B) expression in numerous bacterial species.

-	~~Authors~~:	+	The mechanism of a formaldehyde-sensing transcriptional regulator.,Denby KJ, Iwig J, Bisson C, Westwood J, Rolfe MD, Sedelnikova SE, Higgins K, Maroney MJ, Baker PJ, Chivers PT, Green J Sci Rep. 2016 Dec 9;6:38879. doi: 10.1038/srep38879. PMID:27934966<ref>PMID:27934966</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5lbm" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Baker, P J]]
		+	[[Category: Bisson, C]]
		+	[[Category: Chivers, P T]]
		+	[[Category: Green, J]]
		+	[[Category: Csor/rcnr escherichia coli frmr methylene bridge]]
		+	[[Category: Transcription]]

OCA at 13:17, 26 July 2016

2016-07-26T13:17:31Z

←Older revision		Revision as of 13:17, 26 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5lbm is ON HOLD	+	The entry 5lbm is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5lbm" [edit=sysop:move=sysop]

2016-06-23T21:59:56Z

Protected "5lbm" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:59, 23 June 2016

OCA: New page: '''Unreleased structure''' The entry 5lbm is ON HOLD Authors: Description: Category: Unreleased Structures

2016-06-23T21:59:55Z

New page: '''Unreleased structure''' The entry 5lbm is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5lbm is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]