5m87 - Revision history

OCA at 18:29, 1 November 2023

2023-11-01T18:29:56Z

←Older revision		Revision as of 18:29, 1 November 2023
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	<StructureSection load='5m87' size='340' side='right'caption='[[5m87]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='5m87' size='340' side='right'caption='[[5m87]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M87 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5M87 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m87]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eremococcus_coleocola_ACS-139-V-Col8 Eremococcus coleocola ACS-139-V-Col8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M87 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.3Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5m87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m87 OCA], [~~http~~://pdbe.org/5m87 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5m87 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5m87 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5m87 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m87 OCA], [https://pdbe.org/5m87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m87 RCSB], [https://www.ebi.ac.uk/pdbsum/5m87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m87 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/E4KPW4_9LACT E4KPW4_9LACT]] H(+)-stimulated, divalent metal cation uptake system.[HAMAP-Rule:MF_00221]	+	[https://www.uniprot.org/uniprot/E4KPW4_9LACT E4KPW4_9LACT] H(+)-stimulated, divalent metal cation uptake system.[HAMAP-Rule:MF_00221]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Eremococcus coleocola ACS-139-V-Col8]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arnold~~, F M~~]]	+	[[Category: Arnold FM]]
-	[[Category: Dutzler, R]]	+	[[Category: Dutzler R]]
-	[[Category: Ehrnstorfer~~, I A~~]]	+	[[Category: Ehrnstorfer IA]]
-	[[Category: Laederach, J]]	+	[[Category: Laederach J]]
-	[[Category: Manatschal, C]]	+	[[Category: Manatschal C]]
-	~~[[Category: Transport protein~~]]	+

OCA at 07:11, 19 August 2020

2020-08-19T07:11:31Z

←Older revision		Revision as of 07:11, 19 August 2020
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	==Crystal structure of Eremococcus coleocola manganese transporter==		==Crystal structure of Eremococcus coleocola manganese transporter==
-	<StructureSection load='5m87' size='340' side='right' caption='[[5m87]], [[Resolution\|resolution]] 3.30Å' scene=''>	+	<StructureSection load='5m87' size='340' side='right'caption='[[5m87]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M87 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5M87 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M87 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M87 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5m87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m87 OCA], [http://pdbe.org/5m87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m87 RCSB], [http://www.ebi.ac.uk/pdbsum/5m87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m87 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m87 OCA], [http://pdbe.org/5m87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m87 RCSB], [http://www.ebi.ac.uk/pdbsum/5m87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m87 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Arnold, F M]]		[[Category: Arnold, F M]]
	[[Category: Dutzler, R]]		[[Category: Dutzler, R]]

OCA at 07:51, 18 January 2017

2017-01-18T07:51:25Z

←Older revision		Revision as of 07:51, 18 January 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5m87 is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of Eremococcus coleocola manganese transporter==
		+	<StructureSection load='5m87' size='340' side='right' caption='[[5m87]], [[Resolution\|resolution]] 3.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5m87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M87 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m87 OCA], [http://pdbe.org/5m87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m87 RCSB], [http://www.ebi.ac.uk/pdbsum/5m87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m87 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/E4KPW4_9LACT E4KPW4_9LACT]] H(+)-stimulated, divalent metal cation uptake system.[HAMAP-Rule:MF_00221]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Secondary active transporters of the SLC11/NRAMP family catalyse the uptake of iron and manganese into cells. These proteins are highly conserved across all kingdoms of life and thus likely share a common transport mechanism. Here we describe the structural and functional properties of the prokaryotic SLC11 transporter EcoDMT. Its crystal structure reveals a previously unknown outward-facing state of the protein family. In proteoliposomes EcoDMT mediates proton-coupled uptake of manganese at low micromolar concentrations. Mutants of residues in the transition-metal ion-binding site severely affect transport, whereas a mutation of a conserved histidine located near this site results in metal ion transport that appears uncoupled to proton transport. Combined with previous results, our study defines the conformational changes underlying transition-metal ion transport in the SLC11 family and it provides molecular insight to its coupling to protons.

-	~~Authors~~:	+	Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.,Ehrnstorfer IA, Manatschal C, Arnold FM, Laederach J, Dutzler R Nat Commun. 2017 Jan 6;8:14033. doi: 10.1038/ncomms14033. PMID:28059071<ref>PMID:28059071</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5m87" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arnold, F M]]
		+	[[Category: Dutzler, R]]
		+	[[Category: Ehrnstorfer, I A]]
		+	[[Category: Laederach, J]]
		+	[[Category: Manatschal, C]]
		+	[[Category: Transport protein]]

OCA at 16:28, 9 December 2016

2016-12-09T16:28:48Z

←Older revision		Revision as of 16:28, 9 December 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5m87 is ON HOLD	+	The entry 5m87 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5m87" [edit=sysop:move=sysop]

2016-11-02T16:08:39Z

Protected "5m87" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:08, 2 November 2016

OCA: New page: '''Unreleased structure''' The entry 5m87 is ON HOLD Authors: Description: Category: Unreleased Structures

2016-11-02T16:08:38Z

New page: '''Unreleased structure''' The entry 5m87 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5m87 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]