5m9o - Revision history

OCA at 18:33, 1 November 2023

2023-11-01T18:33:17Z

←Older revision		Revision as of 18:33, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='5m9o' size='340' side='right'caption='[[5m9o]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='5m9o' size='340' side='right'caption='[[5m9o]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5M9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M9O FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=2MR:N3~~,~~+N4-DIMETHYLARGININE'>2MR</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~SND1, TDRD11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [~~http~~://pdbe.org/5m9o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [https://pdbe.org/5m9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [https://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN]] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>	+	[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	[[Category: Chan, C]]	+	[[Category: Chan C]]
-	[[Category: ~~Delft, F von~~]]	+	[[Category: Edwards AM]]
-	[[Category: ~~Edwards, A M~~]]	+	[[Category: Fedorov O]]
-	[[Category: ~~Fedorov, O~~]]	+	[[Category: Knapp S]]
-	[[Category: ~~Knapp, S~~]]	+	[[Category: La Thangue NB]]
-	[[Category: Moehlenbrink, J]]	+	[[Category: Moehlenbrink J]]
-	[[Category: Nunez-Alonso, G]]	+	[[Category: Nunez-Alonso G]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Savitsky P]]
-	[[Category: Savitsky, P]]	+	[[Category: Siejka P]]
-	[[Category: Siejka, P]]	+	[[Category: Sorrell FJ]]
-	[[Category: Sorrell~~, F J~~]]	+	[[Category: Tallant C]]
-	[[Category: Tallant, C]]	+	[[Category: Von Delft F]]
-	[[Category: ~~Thangue, N B.La]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcriptional coactivator~~]]	+

OCA at 07:12, 19 August 2020

2020-08-19T07:12:54Z

←Older revision		Revision as of 07:12, 19 August 2020
Line 1:		Line 1:

	==Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide==		==Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide==
-	<StructureSection load='5m9o' size='340' side='right' caption='[[5m9o]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='5m9o' size='340' side='right'caption='[[5m9o]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5M9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M9O FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [http://pdbe.org/5m9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [http://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SND1, TDRD11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [http://pdbe.org/5m9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [http://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA: Protected "5m9o" [edit=sysop:move=sysop]

2016-12-11T02:18:31Z

Protected "5m9o" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:18, 11 December 2016

OCA: New page: ==Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide== == Structural highlights ==
<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M9O FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [http://pdbe.org/5m9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [http://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN]] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
== References ==
<references/>
TOC
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Chan, C]]
[[Category: Delft, F von]]
[[Category: Edwards, A M]]
[[Category: Fedorov, O]]
[[Category: Knapp, S]]
[[Category: Moehlenbrink, J]]
[[Category: Nunez-Alonso, G]]
[[Category: Structural genomic]]
[[Category: Savitsky, P]]
[[Category: Siejka, P]]
[[Category: Sorrell, F J]]
[[Category: Tallant, C]]
[[Category: Thangue, N B.La]]
[[Category: Sgc]]
[[Category: Transcription]]
[[Category: Transcriptional coactivator]]