5me3 - Revision history

OCA at 18:40, 1 November 2023

2023-11-01T18:40:26Z

←Older revision		Revision as of 18:40, 1 November 2023
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	<StructureSection load='5me3' size='340' side='right'caption='[[5me3]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='5me3' size='340' side='right'caption='[[5me3]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5me3]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ashgo Ashgo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5ME3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5me3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Eremothecium_gossypii_ATCC_10895 Eremothecium gossypii ATCC 10895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ME3 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.85Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">SCC2, AGL133W ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=284811 ASHGO])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5me3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me3 OCA], [https://pdbe.org/5me3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5me3 RCSB], [https://www.ebi.ac.uk/pdbsum/5me3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5me3 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5me3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me3 OCA], [~~http~~://pdbe.org/5me3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5me3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5me3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5me3 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SCC2_ASHGO SCC2_ASHGO]] Plays a structural role in chromatin. Probably involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity).	+	[https://www.uniprot.org/uniprot/SCC2_ASHGO SCC2_ASHGO] Plays a structural role in chromatin. Probably involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ashgo~~]]	+	[[Category: Eremothecium gossypii ATCC 10895]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chao~~, W C.H~~]]	+	[[Category: Chao WCH]]
-	[[Category: Singleton~~, M R]]~~	+	[[Category: Singleton MR]]
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Cohesin loader]]~~	+
-	~~[[Category: Heat repeat]]~~	+
-	~~[[Category: Scc2~~]]	+

OCA at 07:16, 19 August 2020

2020-08-19T07:16:43Z

←Older revision		Revision as of 07:16, 19 August 2020
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	==Structure of the Scc2 C-terminus==		==Structure of the Scc2 C-terminus==
-	<StructureSection load='5me3' size='340' side='right' caption='[[5me3]], [[Resolution\|resolution]] 2.85Å' scene=''>	+	<StructureSection load='5me3' size='340' side='right'caption='[[5me3]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5me3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ME3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5me3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ashgo Ashgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ME3 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5me3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me3 OCA], [http://pdbe.org/5me3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5me3 RCSB], [http://www.ebi.ac.uk/pdbsum/5me3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5me3 ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SCC2, AGL133W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284811 ASHGO])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5me3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me3 OCA], [http://pdbe.org/5me3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5me3 RCSB], [http://www.ebi.ac.uk/pdbsum/5me3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5me3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ashgo]]
		+	[[Category: Large Structures]]
	[[Category: Chao, W C.H]]		[[Category: Chao, W C.H]]
	[[Category: Singleton, M R]]		[[Category: Singleton, M R]]

OCA at 07:57, 18 January 2017

2017-01-18T07:57:17Z

←Older revision		Revision as of 07:57, 18 January 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5me3 is ~~ON HOLD until Paper~~ Publication	+	==Structure of the Scc2 C-terminus==
		+	<StructureSection load='5me3' size='340' side='right' caption='[[5me3]], [[Resolution\|resolution]] 2.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5me3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ME3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ME3 FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5me3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5me3 OCA], [http://pdbe.org/5me3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5me3 RCSB], [http://www.ebi.ac.uk/pdbsum/5me3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5me3 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SCC2_ASHGO SCC2_ASHGO]] Plays a structural role in chromatin. Probably involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The functions of cohesin are central to genome integrity, chromosome organization and transcription regulation through its prevention of premature sister-chromatid separation and the formation of DNA loops. The loading of cohesin onto chromatin depends on the Scc2-Scc4 complex; however, little is known about how it stimulates the cohesion-loading activity. Here we determine the large 'hook' structure of Scc2 responsible for catalysing cohesin loading. We identify key Scc2 surfaces that are crucial for cohesin loading in vivo. With the aid of previously determined structures and homology modelling, we derive a pseudo-atomic structure of the full-length Scc2-Scc4 complex. Finally, using recombinantly purified Scc2-Scc4 and cohesin, we performed crosslinking mass spectrometry and interaction assays that suggest Scc2-Scc4 uses its modular structure to make multiple contacts with cohesin.

-	~~Authors~~:	+	Structure of the cohesin loader Scc2.,Chao WC, Murayama Y, Munoz S, Jones AW, Wade BO, Purkiss AG, Hu XW, Borg A, Snijders AP, Uhlmann F, Singleton MR Nat Commun. 2017 Jan 6;8:13952. doi: 10.1038/ncomms13952. PMID:28059076<ref>PMID:28059076</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5me3" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chao, W C.H]]
		+	[[Category: Singleton, M R]]
		+	[[Category: Cell cycle]]
		+	[[Category: Cohesin loader]]
		+	[[Category: Heat repeat]]
		+	[[Category: Scc2]]

OCA at 13:47, 4 January 2017

2017-01-04T13:47:35Z

←Older revision		Revision as of 13:47, 4 January 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5me3 is ON HOLD	+	The entry 5me3 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5me3" [edit=sysop:move=sysop]

2016-12-09T16:42:22Z

Protected "5me3" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:42, 9 December 2016

OCA: New page: '''Unreleased structure''' The entry 5me3 is ON HOLD Authors: Description: Category: Unreleased Structures

2016-12-09T16:42:21Z

New page: '''Unreleased structure''' The entry 5me3 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5me3 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]