5mf4 - Revision history

OCA at 18:41, 1 November 2023

2023-11-01T18:41:40Z

←Older revision		Revision as of 18:41, 1 November 2023
Line 1:		Line 1:

	==Tubulin-Dictyostatin complex==		==Tubulin-Dictyostatin complex==
-	<StructureSection load='5mf4' size='340' side='right' caption='[[5mf4]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='5mf4' size='340' side='right'caption='[[5mf4]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5mf4]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [~~http~~://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~] and [~~http~~://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MF4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5MF4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5mf4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MF4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7LZ:(3~{Z},5~{E},7~{R},8~{S},10~{S},11~{Z},13~{S},14~{R},15~{S},17~{S},20~{R},21~{S},22~{S})-22-[(2~{S},3~{Z})-hexa-3,5-dien-2-yl]-7,13,15,17,21-pentamethyl-8,10,14,20-tetrakis(oxidanyl)-1-oxacyclodocosa-3,5,11-trien-2-one'>7LZ</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lxt\|5lxt]], [[5lxs\|5lxs]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7LZ:(3~{Z},5~{E},7~{R},8~{S},10~{S},11~{Z},13~{S},14~{R},15~{S},17~{S},20~{R},21~{S},22~{S})-22-[(2~{S},3~{Z})-hexa-3,5-dien-2-yl]-7,13,15,17,21-pentamethyl-8,10,14,20-tetrakis(oxidanyl)-1-oxacyclodocosa-3,5,11-trien-2-one'>7LZ</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Stmn4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), TTL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mf4 OCA], [https://pdbe.org/5mf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mf4 RCSB], [https://www.ebi.ac.uk/pdbsum/5mf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mf4 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5mf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mf4 OCA], [~~http~~://pdbe.org/5mf4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5mf4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5mf4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5mf4 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 21:

	==See Also==		==See Also==
-	*[[Stathmin\|Stathmin]]	+	*[[Stathmin-4 3D structures\|Stathmin-4 3D structures]]
-	*[[Tubulin\|Tubulin]]	+
-	*[[User:Alisa Cario\|User:Alisa Cario]]	+
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
-	[[Category: ~~Buffalo rat~~]]	+	[[Category: Gallus gallus]]
-	[[Category: ~~Chick~~]]	+	[[Category: Large Structures]]
-	[[Category: Barasoain, I]]	+	[[Category: Rattus norvegicus]]
-	[[Category: Bargsten, K]]	+	[[Category: Barasoain I]]
-	[[Category: Diaz~~, J F~~]]	+	[[Category: Bargsten K]]
-	[[Category: Gago, F]]	+	[[Category: Diaz JF]]
-	[[Category: Gardner~~, N M~~]]	+	[[Category: Gago F]]
-	[[Category: Gomez-Rubio, E]]	+	[[Category: Gardner NM]]
-	[[Category: Meyer, A]]	+	[[Category: Gomez-Rubio E]]
-	[[Category: Naylor~~, G J~~]]	+	[[Category: Meyer A]]
-	[[Category: Nogales, A]]	+	[[Category: Naylor GJ]]
-	[[Category: Paterson, I]]	+	[[Category: Nogales A]]
-	[[Category: Prota~~, A E~~]]	+	[[Category: Paterson I]]
-	[[Category: Redondo-Horcajo, M]]	+	[[Category: Prota AE]]
-	[[Category: Sanchez-Murcia~~, P A~~]]	+	[[Category: Redondo-Horcajo M]]
-	[[Category: Steinmetz~~, M O~~]]	+	[[Category: Sanchez-Murcia PA]]
-	[[Category: Trigili, C]]	+	[[Category: Steinmetz MO]]
-	~~[[Category: Cell cycle]]~~	+	[[Category: Trigili C]]
-	~~[[Category: Cytoskeleton]]~~	+
-	~~[[Category: Microtubule]]~~	+
-	~~[[Category: Tubulin fold~~]]	+

OCA at 07:47, 29 August 2018

2018-08-29T07:47:00Z

←Older revision		Revision as of 07:47, 29 August 2018
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).		[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A combined biochemical, structural, and cell biology characterization of dictyostatin is described, which enables an improved understanding of the structural determinants responsible for the high-affinity binding of this anticancer agent to the taxane site in microtubules (MTs). The study reveals that this macrolide is highly optimized for MT binding and that only a few of the structural modifications featured in a library of synthetic analogues resulted in small gains in binding affinity. The high efficiency of the dictyostatin chemotype in overcoming various kinds of clinically relevant resistance mechanisms highlights its potential for therapeutic development for the treatment of drug-resistant tumors. A structural explanation is advanced to account for the synergy observed between dictyostatin and taxanes on the basis of their differential effects on the MT lattice. The X-ray crystal structure of a tubulin-dictyostatin complex and additional molecular modeling have allowed the rationalization of the structure-activity relationships for a set of synthetic dictyostatin analogues, including the highly active hybrid 12 with discodermolide. Altogether, the work reported here is anticipated to facilitate the improved design and synthesis of more efficacious dictyostatin analogues and hybrids with other MT-stabilizing agents.
		+
		+	Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.,Trigili C, Barasoain I, Sanchez-Murcia PA, Bargsten K, Redondo-Horcajo M, Nogales A, Gardner NM, Meyer A, Naylor GJ, Gomez-Rubio E, Gago F, Steinmetz MO, Paterson I, Prota AE, Diaz JF ACS Omega. 2016 Dec 31;1(6):1192-1204. doi: 10.1021/acsomega.6b00317. Epub 2016, Dec 13. PMID:30023505<ref>PMID:30023505</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5mf4" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Stathmin\|Stathmin]]
		+	*[[Tubulin\|Tubulin]]
		+	*[[User:Alisa Cario\|User:Alisa Cario]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:19, 15 November 2017

2017-11-15T14:19:50Z

←Older revision		Revision as of 14:19, 15 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5mf4 ~~is ON HOLD until Paper Publication~~	+	==Tubulin-Dictyostatin complex==
-		+	<StructureSection load='5mf4' size='340' side='right' caption='[[5mf4]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~Authors~~: ~~Trigili~~, C., ~~Barasoain~~, I., ~~Sanchez~~-~~Murcia~~, ~~P.A.~~, ~~Bargsten~~, K., ~~Redondo~~-~~Horcajo~~, M., ~~Nogales~~, A., ~~Gardner~~, ~~N.M.~~, ~~Meyer~~, A., ~~Naylor~~, ~~G.J.~~, ~~Gomez~~-~~Rubio~~, E., ~~Gago~~, F., ~~Steinmetz~~, M.O., ~~Paterson, I~~., ~~Prota~~, A.E., ~~Diaz, J~~.F.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5mf4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MF4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MF4 FirstGlance]. <br>
-	~~Description~~: Tubulin-~~Dictyostatin complex~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7LZ:(3~{Z},5~{E},7~{R},8~{S},10~{S},11~{Z},13~{S},14~{R},15~{S},17~{S},20~{R},21~{S},22~{S})-22-[(2~{S},3~{Z})-hexa-3,5-dien-2-yl]-7,13,15,17,21-pentamethyl-8,10,14,20-tetrakis(oxidanyl)-1-oxacyclodocosa-3,5,11-trien-2-one'>7LZ</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5lxt\|5lxt]], [[5lxs\|5lxs]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Stmn4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), TTL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mf4 OCA], [http://pdbe.org/5mf4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mf4 RCSB], [http://www.ebi.ac.uk/pdbsum/5mf4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mf4 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bos taurus]]
		+	[[Category: Buffalo rat]]
		+	[[Category: Chick]]
		+	[[Category: Barasoain, I]]
		+	[[Category: Bargsten, K]]
		+	[[Category: Diaz, J F]]
		+	[[Category: Gago, F]]
		+	[[Category: Gardner, N M]]
	[[Category: Gomez-Rubio, E]]		[[Category: Gomez-Rubio, E]]
-	[[Category: ~~Sanchez-Murcia~~, P.A]]	+	[[Category: Meyer, A]]
-	[[Category: ~~Barasoain~~, ~~I]]~~	+	[[Category: Naylor, G J]]
-	~~[[Category: Prota, A.E~~]]	+
	[[Category: Nogales, A]]		[[Category: Nogales, A]]
		+	[[Category: Paterson, I]]
		+	[[Category: Prota, A E]]
	[[Category: Redondo-Horcajo, M]]		[[Category: Redondo-Horcajo, M]]
-	[[Category: ~~Bargsten~~, K]]	+	[[Category: Sanchez-Murcia, P A]]
-	[[Category: ~~Paterson~~, I]]	+	[[Category: Steinmetz, M O]]
	[[Category: Trigili, C]]		[[Category: Trigili, C]]
-	[[Category: ~~Diaz, J.F~~]]	+	[[Category: Cell cycle]]
-	[[Category: ~~Gardner, N.M~~]]	+	[[Category: Cytoskeleton]]
-	[[Category: ~~Steinmetz, M.O~~]]	+	[[Category: Microtubule]]
-	[[Category: ~~Meyer, A]]~~	+	[[Category: Tubulin fold]]
-	~~[[Category: Naylor, G.J]]~~	+
-	~~[[Category: Gago, F~~]]	+

OCA at 11:14, 9 March 2017

2017-03-09T11:14:58Z

←Older revision		Revision as of 11:14, 9 March 2017
Line 7:		Line 7:
	Description: Tubulin-Dictyostatin complex		Description: Tubulin-Dictyostatin complex
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Gomez-Rubio, E]]
		+	[[Category: Sanchez-Murcia, P.A]]
	[[Category: Barasoain, I]]		[[Category: Barasoain, I]]
	[[Category: Prota, A.E]]		[[Category: Prota, A.E]]
	[[Category: Nogales, A]]		[[Category: Nogales, A]]
		+	[[Category: Redondo-Horcajo, M]]
	[[Category: Bargsten, K]]		[[Category: Bargsten, K]]
	[[Category: Paterson, I]]		[[Category: Paterson, I]]
		+	[[Category: Trigili, C]]
	[[Category: Diaz, J.F]]		[[Category: Diaz, J.F]]
	[[Category: Gardner, N.M]]		[[Category: Gardner, N.M]]
Line 17:		Line 21:
	[[Category: Meyer, A]]		[[Category: Meyer, A]]
	[[Category: Naylor, G.J]]		[[Category: Naylor, G.J]]
-	[[Category: Gomez-Rubio, E]]
-	[[Category: Sanchez-Murcia, P.A]]
-	[[Category: Redondo-Horcajo, M]]
-	[[Category: Trigili, C]]
	[[Category: Gago, F]]		[[Category: Gago, F]]

OCA at 18:56, 22 December 2016

2016-12-22T18:56:09Z

←Older revision		Revision as of 18:56, 22 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5mf4 is ON HOLD	+	The entry 5mf4 is ON HOLD until Paper Publication

	Authors: Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A., Naylor, G.J., Gomez-Rubio, E., Gago, F., Steinmetz, M.O., Paterson, I., Prota, A.E., Diaz, J.F.		Authors: Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A., Naylor, G.J., Gomez-Rubio, E., Gago, F., Steinmetz, M.O., Paterson, I., Prota, A.E., Diaz, J.F.

-	Description: Tubulin-~~drug4~~ complex	+	Description: Tubulin-Dictyostatin complex
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Barasoain, I]]		[[Category: Barasoain, I]]

OCA: Protected "5mf4" [edit=sysop:move=sysop]

2016-12-09T16:45:28Z

Protected "5mf4" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:45, 9 December 2016

OCA: New page: '''Unreleased structure''' The entry 5mf4 is ON HOLD Authors: Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A.,...

2016-12-09T16:45:26Z

New page: '''Unreleased structure''' The entry 5mf4 is ON HOLD Authors: Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A.,...

New page

'''Unreleased structure'''

The entry 5mf4 is ON HOLD

Authors: Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A., Naylor, G.J., Gomez-Rubio, E., Gago, F., Steinmetz, M.O., Paterson, I., Prota, A.E., Diaz, J.F.

Description: Tubulin-drug4 complex
[[Category: Unreleased Structures]]
[[Category: Barasoain, I]]
[[Category: Prota, A.E]]
[[Category: Nogales, A]]
[[Category: Bargsten, K]]
[[Category: Paterson, I]]
[[Category: Diaz, J.F]]
[[Category: Gardner, N.M]]
[[Category: Steinmetz, M.O]]
[[Category: Meyer, A]]
[[Category: Naylor, G.J]]
[[Category: Gomez-Rubio, E]]
[[Category: Sanchez-Murcia, P.A]]
[[Category: Redondo-Horcajo, M]]
[[Category: Trigili, C]]
[[Category: Gago, F]]