5mqn - Revision history

OCA at 17:44, 8 November 2023

2023-11-08T17:44:47Z

←Older revision		Revision as of 17:44, 8 November 2023
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	<StructureSection load='5mqn' size='340' side='right'caption='[[5mqn]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5mqn' size='340' side='right'caption='[[5mqn]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5mqn]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_thetaiotaomicron"_distaso_1912 "bacillus~~ thetaiotaomicron~~" distaso 1912~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MQN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5MQN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5mqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MQN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>Btheta7330_02599 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~818~~ "~~Bacillus thetaiotaomicron~~" ~~Distaso 1912])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [~~http~~://pdbe.org/5mqn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [https://pdbe.org/5mqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [https://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8A931_BACTN Q8A931_BACTN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ thetaiotaomicron ~~distaso 1912~~]]	+	[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Basle, A]]	+	[[Category: Basle A]]
-	[[Category: Cartmell, A]]	+	[[Category: Cartmell A]]
-	[[Category: Gilbert~~, H J~~]]	+	[[Category: Gilbert HJ]]
-	[[Category: Labourel, A]]	+	[[Category: Labourel A]]
-	[[Category: Luis~~, A S~~]]	+	[[Category: Luis AS]]
-	[[Category: Ndeh, D]]	+	[[Category: Ndeh D]]
-	[[Category: Rogowski, A]]	+	[[Category: Rogowski A]]
-	[[Category: Venditto, I]]	+	[[Category: Venditto I]]
-	~~[[Category: Cazy family 106]]~~	+
-	~~[[Category: Glycoside hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Plant pectin]]~~	+
-	~~[[Category: Rhamnosidase~~]]	+

OCA at 07:26, 19 August 2020

2020-08-19T07:26:18Z

←Older revision		Revision as of 07:26, 19 August 2020
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	==Glycoside hydrolase BT_0986==		==Glycoside hydrolase BT_0986==
-	<StructureSection load='5mqn' size='340' side='right' caption='[[5mqn]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5mqn' size='340' side='right'caption='[[5mqn]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5mqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MQN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5MQN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5mqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MQN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MQN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [http://pdbe.org/5mqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [http://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Btheta7330_02599 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=818 "Bacillus thetaiotaomicron" Distaso 1912])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [http://pdbe.org/5mqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [http://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus thetaiotaomicron distaso 1912]]
		+	[[Category: Large Structures]]
	[[Category: Basle, A]]		[[Category: Basle, A]]
	[[Category: Cartmell, A]]		[[Category: Cartmell, A]]

OCA at 07:03, 5 April 2017

2017-04-05T07:03:17Z

←Older revision		Revision as of 07:03, 5 April 2017
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [http://pdbe.org/5mqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [http://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [http://pdbe.org/5mqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [http://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The metabolism of carbohydrate polymers drives microbial diversity in the human gut microbiota. It is unclear, however, whether bacterial consortia or single organisms are required to depolymerize highly complex glycans. Here we show that the gut bacterium Bacteroides thetaiotaomicron uses the most structurally complex glycan known: the plant pectic polysaccharide rhamnogalacturonan-II, cleaving all but 1 of its 21 distinct glycosidic linkages. The deconstruction of rhamnogalacturonan-II side chains and backbone are coordinated to overcome steric constraints, and the degradation involves previously undiscovered enzyme families and catalytic activities. The degradation system informs revision of the current structural model of rhamnogalacturonan-II and highlights how individual gut bacteria orchestrate manifold enzymes to metabolize the most challenging glycan in the human diet.
		+
		+	Complex pectin metabolism by gut bacteria reveals novel catalytic functions.,Ndeh D, Rogowski A, Cartmell A, Luis AS, Basle A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A, Terrapon N, Buffetto F, Nepogodiev S, Xiao Y, Field RA, Zhu Y, O'Neill MA, Urbanowicz BR, York WS, Davies GJ, Abbott DW, Ralet MC, Martens EC, Henrissat B, Gilbert HJ Nature. 2017 Mar 22. doi: 10.1038/nature21725. PMID:28329766<ref>PMID:28329766</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5mqn" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 16:23, 22 March 2017

2017-03-22T16:23:55Z

←Older revision		Revision as of 16:23, 22 March 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5mqn ~~is ON HOLD until Paper Publication~~	+	==Glycoside hydrolase BT_0986==
-		+	<StructureSection load='5mqn' size='340' side='right' caption='[[5mqn]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Basle, A~~.~~, Ndeh, D~~.~~, Rogowski, A~~.~~, Cartmell, A~~.~~, Luis, A~~.S.~~, Venditto, I~~.~~, Labourel, A~~.~~, Gilbert, H.J~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5mqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MQN FirstGlance]. <br>
-	~~Description: Glycoside hydrolase BT_0986~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mqn OCA], [http://pdbe.org/5mqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mqn RCSB], [http://www.ebi.ac.uk/pdbsum/5mqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mqn ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Luis~~, A.S]]	+	</table>
-	[~~[Category~~: ~~Ndeh~~, D]]	+	__TOC__
-	[[Category: ~~Venditto~~, I]]	+	</StructureSection>
		+	[[Category: Basle, A]]
	[[Category: Cartmell, A]]		[[Category: Cartmell, A]]
		+	[[Category: Gilbert, H J]]
	[[Category: Labourel, A]]		[[Category: Labourel, A]]
-	[[Category: ~~Basle~~, A]]	+	[[Category: Luis, A S]]
-	[[Category: ~~Gilbert~~, ~~H.J~~]]	+	[[Category: Ndeh, D]]
	[[Category: Rogowski, A]]		[[Category: Rogowski, A]]
		+	[[Category: Venditto, I]]
		+	[[Category: Cazy family 106]]
		+	[[Category: Glycoside hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Plant pectin]]
		+	[[Category: Rhamnosidase]]

OCA at 11:33, 9 March 2017

2017-03-09T11:33:20Z

←Older revision		Revision as of 11:33, 9 March 2017
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	Description: Glycoside hydrolase BT_0986		Description: Glycoside hydrolase BT_0986
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Cartmell, A]]
-	[[Category: Labourel, A]]
-	[[Category: Gilbert, H.J]]
	[[Category: Luis, A.S]]		[[Category: Luis, A.S]]
	[[Category: Ndeh, D]]		[[Category: Ndeh, D]]
	[[Category: Venditto, I]]		[[Category: Venditto, I]]
		+	[[Category: Cartmell, A]]
		+	[[Category: Labourel, A]]
	[[Category: Basle, A]]		[[Category: Basle, A]]
		+	[[Category: Gilbert, H.J]]
	[[Category: Rogowski, A]]		[[Category: Rogowski, A]]

OCA: Protected "5mqn" [edit=sysop:move=sysop]

2017-01-02T13:53:33Z

Protected "5mqn" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:53, 2 January 2017

OCA: New page: '''Unreleased structure''' The entry 5mqn is ON HOLD until Paper Publication Authors: Basle, A., Ndeh, D., Rogowski, A., Cartmell, A., Luis, A.S., Venditto, I., Labourel, A., Gilbert, H...

2017-01-02T13:53:31Z

New page: '''Unreleased structure''' The entry 5mqn is ON HOLD until Paper Publication Authors: Basle, A., Ndeh, D., Rogowski, A., Cartmell, A., Luis, A.S., Venditto, I., Labourel, A., Gilbert, H...

New page

'''Unreleased structure'''

The entry 5mqn is ON HOLD until Paper Publication

Authors: Basle, A., Ndeh, D., Rogowski, A., Cartmell, A., Luis, A.S., Venditto, I., Labourel, A., Gilbert, H.J.

Description: Glycoside hydrolase BT_0986
[[Category: Unreleased Structures]]
[[Category: Cartmell, A]]
[[Category: Labourel, A]]
[[Category: Gilbert, H.J]]
[[Category: Luis, A.S]]
[[Category: Ndeh, D]]
[[Category: Venditto, I]]
[[Category: Basle, A]]
[[Category: Rogowski, A]]