5oao - Revision history

OCA at 10:22, 14 June 2023

2023-06-14T10:22:51Z

←Older revision		Revision as of 10:22, 14 June 2023
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	==Solution structure of the complexed RCD1-RST==		==Solution structure of the complexed RCD1-RST==
-	<StructureSection load='5oao' size='340' side='right'caption='[[5oao~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='5oao' size='340' side='right'caption='[[5oao]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5OAO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OAO FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RCD1, ATP8, CEO1, At1g32230, F3C3.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [https://pdbe.org/5oao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [https://www.ebi.ac.uk/pdbsum/5oao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [~~http~~://pdbe.org/5oao PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5oao PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RCD1_ARATH RCD1_ARATH]] Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro.<ref>PMID:11018516</ref> <ref>PMID:11041881</ref> <ref>PMID:14657410</ref> <ref>PMID:15208394</ref> <ref>PMID:15728341</ref> <ref>PMID:16926493</ref> <ref>PMID:19548978</ref> <ref>PMID:19625634</ref> <ref>PMID:20226034</ref> <ref>PMID:21172813</ref>	+	[https://www.uniprot.org/uniprot/RCD1_ARATH RCD1_ARATH] Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro.<ref>PMID:11018516</ref> <ref>PMID:11041881</ref> <ref>PMID:14657410</ref> <ref>PMID:15208394</ref> <ref>PMID:15728341</ref> <ref>PMID:16926493</ref> <ref>PMID:19548978</ref> <ref>PMID:19625634</ref> <ref>PMID:20226034</ref> <ref>PMID:21172813</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bugge, K]]	+	[[Category: Bugge K]]
-	[[Category: Kragelund~~, B B~~]]	+	[[Category: Kragelund BB]]
-	[[Category: Skriver, K]]	+	[[Category: Skriver K]]
-	[[Category: Staby, L]]	+	[[Category: Staby L]]
-	~~[[Category: Alpha-alpha hairpin]]~~	+
-	~~[[Category: Hub]]~~	+
-	~~[[Category: L-glove]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Transcription factor binding~~]]	+

OCA at 13:17, 10 May 2019

2019-05-10T13:17:18Z

←Older revision		Revision as of 13:17, 10 May 2019
Line 1:		Line 1:

	==Solution structure of the complexed RCD1-RST==		==Solution structure of the complexed RCD1-RST==
-	<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='5oao' size='340' side='right'caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RCD1, ATP8, CEO1, At1g32230, F3C3.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Bugge, K]]		[[Category: Bugge, K]]
	[[Category: Kragelund, B B]]		[[Category: Kragelund, B B]]

OCA at 06:26, 9 May 2018

2018-05-09T06:26:27Z

←Older revision		Revision as of 06:26, 9 May 2018
Line 3:		Line 3:
	<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Arath Arath]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RCD1, ATP8, CEO1, At1g32230, F3C3.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arath]]
	[[Category: Bugge, K]]		[[Category: Bugge, K]]
	[[Category: Kragelund, B B]]		[[Category: Kragelund, B B]]

OCA at 05:51, 25 April 2018

2018-04-25T05:51:15Z

←Older revision		Revision as of 05:51, 25 April 2018
Line 3:		Line 3:
	<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RCD1, ATP8, CEO1, At1g32230, F3C3.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/RCD1_ARATH RCD1_ARATH]] Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro.<ref>PMID:11018516</ref> <ref>PMID:11041881</ref> <ref>PMID:14657410</ref> <ref>PMID:15208394</ref> <ref>PMID:15728341</ref> <ref>PMID:16926493</ref> <ref>PMID:19548978</ref> <ref>PMID:19625634</ref> <ref>PMID:20226034</ref> <ref>PMID:21172813</ref>		[[http://www.uniprot.org/uniprot/RCD1_ARATH RCD1_ARATH]] Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro.<ref>PMID:11018516</ref> <ref>PMID:11041881</ref> <ref>PMID:14657410</ref> <ref>PMID:15208394</ref> <ref>PMID:15728341</ref> <ref>PMID:16926493</ref> <ref>PMID:19548978</ref> <ref>PMID:19625634</ref> <ref>PMID:20226034</ref> <ref>PMID:21172813</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Communication within cells relies on a few protein nodes called hubs, which organize vast interactomes with many partners. Frequently, hub proteins are intrinsically disordered conferring multi-specificity and dynamic communication. Conversely, folded hub proteins may organize networks using disordered partners. In this work, the structure of the RST domain, a unique folded hub, is solved by nuclear magnetic resonance spectroscopy and small-angle X-ray scattering, and its complex with a region of the transcription factor DREB2A is provided through data-driven HADDOCK modeling and mutagenesis analysis. The RST fold is unique, but similar structures are identified in the PAH (paired amphipathic helix), TAFH (TATA-box-associated factor homology), and NCBD (nuclear coactivator binding domain) domains. We designate them as a group the alphaalpha hubs, as they share an alphaalpha-hairpin super-secondary motif, which serves as an organizing platform for malleable helices of varying topology. This allows for partner adaptation, exclusion, and selection. Our findings provide valuable insights into structural features enabling signaling fidelity.
		+
		+	Structure of Radical-Induced Cell Death1 Hub Domain Reveals a Common alphaalpha-Scaffold for Disorder in Transcriptional Networks.,Bugge K, Staby L, Kemplen KR, O'Shea C, Bendsen SK, Jensen MK, Olsen JG, Skriver K, Kragelund BB Structure. 2018 Apr 12. pii: S0969-2126(18)30094-7. doi:, 10.1016/j.str.2018.03.013. PMID:29657132<ref>PMID:29657132</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5oao" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Bugge, K]]		[[Category: Bugge, K]]
	[[Category: Kragelund, B B]]		[[Category: Kragelund, B B]]

OCA at 05:36, 18 April 2018

2018-04-18T05:36:41Z

←Older revision		Revision as of 05:36, 18 April 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5oao is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Solution structure of the complexed RCD1-RST==
-		+	<StructureSection load='5oao' size='340' side='right' caption='[[5oao]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5oao]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OAO FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oao OCA], [http://pdbe.org/5oao PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oao RCSB], [http://www.ebi.ac.uk/pdbsum/5oao PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oao ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RCD1_ARATH RCD1_ARATH]] Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro.<ref>PMID:11018516</ref> <ref>PMID:11041881</ref> <ref>PMID:14657410</ref> <ref>PMID:15208394</ref> <ref>PMID:15728341</ref> <ref>PMID:16926493</ref> <ref>PMID:19548978</ref> <ref>PMID:19625634</ref> <ref>PMID:20226034</ref> <ref>PMID:21172813</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bugge, K]]
		+	[[Category: Kragelund, B B]]
		+	[[Category: Skriver, K]]
		+	[[Category: Staby, L]]
		+	[[Category: Alpha-alpha hairpin]]
		+	[[Category: Hub]]
		+	[[Category: L-glove]]
		+	[[Category: Protein binding]]
		+	[[Category: Transcription factor binding]]

OCA: Protected "5oao" [edit=sysop:move=sysop]

2017-09-27T12:13:17Z

Protected "5oao" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:13, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5oao is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

2017-09-27T12:13:16Z

New page: '''Unreleased structure''' The entry 5oao is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5oao is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]