5qag - Revision history

OCA at 09:53, 15 November 2023

2023-11-15T09:53:27Z

←Older revision		Revision as of 09:53, 15 November 2023
Line 3:		Line 3:
	<StructureSection load='5qag' size='340' side='right'caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5qag' size='340' side='right'caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus~~ pneumoniae~~" (schroeter 1886) flugge 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QAG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QAG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1~~,2~~-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:~~3~~-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~KCX~~:~~LYSINE~~+~~NZ-CARBOXYLIC+ACID~~'>~~KCX~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">bla OXA-48~~, ~~blaOXA~~-~~48, KPE71T_00045 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Beta~~-~~lactamase Beta~~-~~lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [https://pdbe.org/5qag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [https://www.ebi.ac.uk/pdbsum/5qag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [https://pdbe.org/5qag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [https://www.ebi.ac.uk/pdbsum/5qag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6XEC0_KLEPN Q6XEC0_KLEPN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Beta-lactamase~~]]	+	[[Category: Klebsiella pneumoniae]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Leiros~~, H K.S~~]]	+	[[Category: Leiros HKS]]
-	[[Category: Lund~~, B A]]~~	+	[[Category: Lund BA]]
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Fragment]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inhibitor]]~~	+
-	~~[[Category: Oxa]]~~	+
-	~~[[Category: Oxacillinase~~]]	+

OCA at 14:03, 17 November 2021

2021-11-17T14:03:02Z

←Older revision		Revision as of 14:03, 17 November 2021
Line 1:		Line 1:

	==OXA-48 IN COMPLEX WITH COMPOUND 9a==		==OXA-48 IN COMPLEX WITH COMPOUND 9a==
-	<StructureSection load='5qag' size='340' side='right' caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='5qag' size='340' side='right'caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5QAG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QAG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bla OXA-48, blaOXA-48, KPE71T_00045 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bla OXA-48, blaOXA-48, KPE71T_00045 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [~~http~~://pdbe.org/5qag PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5qag PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [https://pdbe.org/5qag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [https://www.ebi.ac.uk/pdbsum/5qag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5qag" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5qag" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
	[[Category: Leiros, H K.S]]		[[Category: Leiros, H K.S]]
	[[Category: Lund, B A]]		[[Category: Lund, B A]]

OCA at 06:50, 14 March 2018

2018-03-14T06:50:44Z

←Older revision		Revision as of 06:50, 14 March 2018
Line 10:		Line 10:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [http://pdbe.org/5qag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [http://www.ebi.ac.uk/pdbsum/5qag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [http://pdbe.org/5qag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [http://www.ebi.ac.uk/pdbsum/5qag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	beta-Lactam antibiotics are of utmost importance when treating bacterial infections in the medical community. However, currently their utility is threatened by the emergence and spread of beta-lactam resistance. The most prevalent resistance mechanism to beta-lactam antibiotics is expression of beta-lactamase enzymes. One way to overcome resistance caused by beta-lactamases, is the development of beta-lactamase inhibitors and today several beta-lactamase inhibitors e.g. avibactam, are approved in the clinic. Our focus is the oxacillinase-48 (OXA-48), an enzyme reported to spread rapidly across the world and commonly identified in Escherichia coli and Klebsiella pneumoniae. To guide inhibitor design, we used diversely substituted 3-aryl and 3-heteroaryl benzoic acids to probe the active site of OXA-48 for useful enzyme-inhibitor interactions. In the presented study, a focused fragment library containing 49 3-substituted benzoic acid derivatives were synthesised and biochemically characterized. Based on crystallographic data from 33 fragment-enzyme complexes, the fragments could be classified into R(1) or R(2) binders by their overall binding conformation in relation to the binding of the R(1) and R(2) side groups of imipenem. Moreover, binding interactions attractive for future inhibitor design were found and their usefulness explored by the rational design and evaluation of merged inhibitors from orthogonally binding fragments. The best inhibitors among the resulting 3,5-disubstituted benzoic acids showed inhibitory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structures revealed non-covalent binding to Arg250, Arg214 and Tyr211 in the active site and the interactions observed with the mono-substituted fragments were also identified in the merged structures.
		+
		+	A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.,Akhter S, Lund BA, Ismael A, Langer M, Isaksson J, Christopeit T, Leiros HS, Bayer A Eur J Med Chem. 2018 Feb 10;145:634-648. doi: 10.1016/j.ejmech.2017.12.085. Epub , 2017 Dec 30. PMID:29348071<ref>PMID:29348071</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5qag" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:17, 22 February 2018

2018-02-22T08:17:13Z

←Older revision		Revision as of 08:17, 22 February 2018
Line 3:		Line 3:
	<StructureSection load='5qag' size='340' side='right' caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5qag' size='340' side='right' caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QAG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QAG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bla OXA-48, blaOXA-48, KPE71T_00045 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [http://pdbe.org/5qag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [http://www.ebi.ac.uk/pdbsum/5qag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [http://pdbe.org/5qag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [http://www.ebi.ac.uk/pdbsum/5qag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>

OCA at 08:23, 10 January 2018

2018-01-10T08:23:43Z

←Older revision		Revision as of 08:23, 10 January 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5qag is ~~ON HOLD~~	+	==OXA-48 IN COMPLEX WITH COMPOUND 9a==
-		+	<StructureSection load='5qag' size='340' side='right' caption='[[5qag]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~Authors~~: ~~Lund~~, B.A., ~~Leiros~~, H.K.S.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5qag]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QAG FirstGlance]. <br>
-	~~Description~~: ~~OXA~~-~~48 IN COMPLEX WITH COMPOUND 9a~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=Q2R:3-(2-methoxycarbonylphenyl)benzoic+acid'>Q2R</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
-	[[Category: Lund, B.A]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	[[Category: ~~Leiros, H.K.S~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qag OCA], [http://pdbe.org/5qag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qag RCSB], [http://www.ebi.ac.uk/pdbsum/5qag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qag ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-lactamase]]
		+	[[Category: Leiros, H K.S]]
		+	[[Category: Lund, B A]]
		+	[[Category: Antibiotic resistance]]
		+	[[Category: Complex]]
		+	[[Category: Fragment]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]
		+	[[Category: Oxa]]
		+	[[Category: Oxacillinase]]

OCA: Protected "5qag" [edit=sysop:move=sysop]

2017-09-27T13:16:58Z

Protected "5qag" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:16, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5qag is ON HOLD Authors: Lund, B.A., Leiros, H.K.S. Description: OXA-48 IN COMPLEX WITH COMPOUND 9a Category: Unreleased Structures [[Category:...

2017-09-27T13:16:57Z

New page: '''Unreleased structure''' The entry 5qag is ON HOLD Authors: Lund, B.A., Leiros, H.K.S. Description: OXA-48 IN COMPLEX WITH COMPOUND 9a Category: Unreleased Structures [[Category:...

New page

'''Unreleased structure'''

The entry 5qag is ON HOLD

Authors: Lund, B.A., Leiros, H.K.S.

Description: OXA-48 IN COMPLEX WITH COMPOUND 9a
[[Category: Unreleased Structures]]
[[Category: Lund, B.A]]
[[Category: Leiros, H.K.S]]