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5qxi - Revision history
2026-04-05T12:29:46Z
Revision history for this page on the wiki
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http://52.214.119.220/wiki/index.php?title=5qxi&diff=4068810&oldid=prev
OCA at 11:28, 21 February 2024
2024-02-21T11:28:37Z
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 11:28, 21 February 2024</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5qxi' size='340' side='right'caption='[[5qxi]], [[Resolution|resolution]] 1.64&Aring;' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5qxi' size='340' side='right'caption='[[5qxi]], [[Resolution|resolution]] 1.64&Aring;' scene=''></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5qxi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QXI OCA]. For a <b>guided tour on the structure components</b> use [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://proteopedia.org/fgij/fg.htm?mol=5QXI FirstGlance]. <br></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5qxi]] is a 1 chain structure <ins style="color: red; font-weight: bold; text-decoration: none;">with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]</ins>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QXI OCA]. For a <b>guided tour on the structure components</b> use [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://proteopedia.org/fgij/fg.htm?mol=5QXI FirstGlance]. <br></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div></td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RGY:(4R,4aS,7aS,9S)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>RGY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TQS:(4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>TQS</scene<del style="color: red; font-weight: bold; text-decoration: none;">></td></tr></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></td></tr><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span</del>></td></tr></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RGY:(4R,4aS,7aS,9S)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>RGY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TQS:(4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>TQS</scene></td></tr></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://proteopedia.org/fgij/fg.htm?mol=5qxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qxi OCA], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://pdbe.org/5qxi PDBe], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://www.rcsb.org/pdb/explore.do?structureId=5qxi RCSB], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://www.ebi.ac.uk/pdbsum/5qxi PDBsum], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://prosat.h-its.org/prosat/prosatexe?pdbcode=5qxi ProSAT]</span></td></tr></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://proteopedia.org/fgij/fg.htm?mol=5qxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qxi OCA], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://pdbe.org/5qxi PDBe], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.rcsb.org/pdb/explore.do?structureId=5qxi RCSB], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.ebi.ac.uk/pdbsum/5qxi PDBsum], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://prosat.h-its.org/prosat/prosatexe?pdbcode=5qxi ProSAT]</span></td></tr></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></table></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></table></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[<del style="color: red; font-weight: bold; text-decoration: none;">[http</del>://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN<del style="color: red; font-weight: bold; text-decoration: none;">]</del>] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref> <del style="color: red; font-weight: bold; text-decoration: none;"> </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref> </div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==See Also==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*[[ATPase family AAA domain-containing protein|ATPase family AAA domain-containing protein]]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Adenosinetriphosphatase</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Homo sapiens</ins>]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Large Structures]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Large Structures]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Arrowsmith<del style="color: red; font-weight: bold; text-decoration: none;">, C H</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Arrowsmith <ins style="color: red; font-weight: bold; text-decoration: none;">CH</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Bountra<del style="color: red; font-weight: bold; text-decoration: none;">, </del>C]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Bountra C]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Collins<del style="color: red; font-weight: bold; text-decoration: none;">, </del>P]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Collins P]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Edwards<del style="color: red; font-weight: bold; text-decoration: none;">, </del>A]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Edwards A]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Fowley<del style="color: red; font-weight: bold; text-decoration: none;">, </del>D]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Fowley D]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Nelson<del style="color: red; font-weight: bold; text-decoration: none;">, </del>A]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Nelson A]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Snee<del style="color: red; font-weight: bold; text-decoration: none;">, </del>M]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Snee M]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Talon<del style="color: red; font-weight: bold; text-decoration: none;">, </del>R]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Talon R]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Von-Delft<del style="color: red; font-weight: bold; text-decoration: none;">, </del>F<del style="color: red; font-weight: bold; text-decoration: none;">]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Von-Delft F]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Hydrolase-hydrolase inhibitor complex]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Pandda]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Sgc - diamond i04-1 fragment screening]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Xchemexplorer</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
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OCA
http://52.214.119.220/wiki/index.php?title=5qxi&diff=3184606&oldid=prev
OCA at 06:44, 8 April 2020
2020-04-08T06:44:37Z
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 06:44, 8 April 2020</td>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The entry </del>5qxi <del style="color: red; font-weight: bold; text-decoration: none;">is ON HOLD </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC587==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><StructureSection load='</ins>5qxi<ins style="color: red; font-weight: bold; text-decoration: none;">' size='340' side='right'caption='[[5qxi]], [[Resolution|resolution]] 1.64&Aring;' scene=''></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Authors</del>: <del style="color: red; font-weight: bold; text-decoration: none;">Snee, M</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Talon</del>, <del style="color: red; font-weight: bold; text-decoration: none;">R.</del>, <del style="color: red; font-weight: bold; text-decoration: none;">Fowley</del>, <del style="color: red; font-weight: bold; text-decoration: none;">D.</del>, <del style="color: red; font-weight: bold; text-decoration: none;">Collins</del>, <del style="color: red; font-weight: bold; text-decoration: none;">P.</del>, <del style="color: red; font-weight: bold; text-decoration: none;">Nelson</del>, <del style="color: red; font-weight: bold; text-decoration: none;">A.</del>, <del style="color: red; font-weight: bold; text-decoration: none;">Arrowsmith</del>, <del style="color: red; font-weight: bold; text-decoration: none;">C</del>.<del style="color: red; font-weight: bold; text-decoration: none;">H</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Bountra</del>, <del style="color: red; font-weight: bold; text-decoration: none;">C</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Edwards</del>, <del style="color: red; font-weight: bold; text-decoration: none;">A</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Von-Delft</del>, <del style="color: red; font-weight: bold; text-decoration: none;">F</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Structural highlights ==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><table><tr><td colspan='2'>[[5qxi]] is a 1 chain structure. Full crystallographic information is available from [http</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">//oca</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">weizmann.ac.il/oca-bin/ocashort?id=5QXI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5QXI FirstGlance]. <br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Description</del>: <del style="color: red; font-weight: bold; text-decoration: none;">PanDDA analysis group deposition --Crystal Structure </del>of <del style="color: red; font-weight: bold; text-decoration: none;">ATAD2 </del>in <del style="color: red; font-weight: bold; text-decoration: none;">complex with PC587</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">2-ETHANEDIOL'>EDO</scene></ins>, <ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='pdbligand=RGY:(4R</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">4aS</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">7aS</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">9S)-3</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">10-dimethyl-5</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">6</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">7</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">7a</ins>,<ins style="color: red; font-weight: bold; text-decoration: none;">8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>RGY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TQS:(4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3,4 5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol'>TQS</scene></td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Unreleased </del>Structures]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">wikipedia</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span></td></tr></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5qxi FirstGlance]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://oca</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">weizmann.ac.il/oca-bin/ocaids?id=5qxi OCA]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://pdbe.org/5qxi PDBe]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://www</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">rcsb.org/pdb/explore.do?structureId=5qxi RCSB]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://www.ebi.ac.uk/pdbsum/5qxi PDBsum]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://prosat</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">h-its.org/prosat/prosatexe?pdbcode=5qxi ProSAT]</span></td></tr></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></table></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Function ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[http</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">//www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN]] May be a transcriptional coactivator </ins>of <ins style="color: red; font-weight: bold; text-decoration: none;">the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role </ins>in <ins style="color: red; font-weight: bold; text-decoration: none;">the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref> </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== References ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><references/></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">__TOC__</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></StructureSection></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Adenosinetriphosphatase]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Large </ins>Structures<ins style="color: red; font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Arrowsmith, C H]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Bountra, C]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Collins, P</ins>]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Edwards, A]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Edwards, A]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Collins</del>, <del style="color: red; font-weight: bold; text-decoration: none;">P</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Fowley</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">D]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Nelson, A</ins>]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Snee, M]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Snee, M]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Bountra, C]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Arrowsmith, C.H]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Nelson, A]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Fowley, D]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Talon, R]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Talon, R]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Von-Delft, F]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Von-Delft, F]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Hydrolase-hydrolase inhibitor complex]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Pandda]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Sgc - diamond i04-1 fragment screening]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Xchemexplorer]]</div></td></tr>
</table>
OCA
http://52.214.119.220/wiki/index.php?title=5qxi&diff=3156330&oldid=prev
OCA: Protected "5qxi" [edit=sysop:move=sysop]
2020-02-19T04:55:25Z
<p>Protected "<a href="/wiki/index.php/5qxi" title="5qxi">5qxi</a>" [edit=sysop:move=sysop]</p>
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 04:55, 19 February 2020</td>
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OCA
http://52.214.119.220/wiki/index.php?title=5qxi&diff=3156329&oldid=prev
OCA: New page: '''Unreleased structure''' The entry 5qxi is ON HOLD Authors: Snee, M., Talon, R., Fowley, D., Collins, P., Nelson, A., Arrowsmith, C.H., Bountra, C., Edwards, A., Von-Delft, F. Descri...
2020-02-19T04:55:23Z
<p>New page: '''Unreleased structure''' The entry 5qxi is ON HOLD Authors: Snee, M., Talon, R., Fowley, D., Collins, P., Nelson, A., Arrowsmith, C.H., Bountra, C., Edwards, A., Von-Delft, F. Descri...</p>
<p><b>New page</b></p><div>'''Unreleased structure'''<br />
<br />
The entry 5qxi is ON HOLD <br />
<br />
Authors: Snee, M., Talon, R., Fowley, D., Collins, P., Nelson, A., Arrowsmith, C.H., Bountra, C., Edwards, A., Von-Delft, F.<br />
<br />
Description: PanDDA analysis group deposition --Crystal Structure of ATAD2 in complex with PC587<br />
[[Category: Unreleased Structures]]<br />
[[Category: Edwards, A]]<br />
[[Category: Collins, P]]<br />
[[Category: Snee, M]]<br />
[[Category: Bountra, C]]<br />
[[Category: Arrowsmith, C.H]]<br />
[[Category: Nelson, A]]<br />
[[Category: Fowley, D]]<br />
[[Category: Talon, R]]<br />
[[Category: Von-Delft, F]]</div>
OCA