5t71 - Revision history

OCA at 15:37, 6 March 2024

2024-03-06T15:37:20Z

←Older revision		Revision as of 15:37, 6 March 2024
Line 1:		Line 1:

	==Human carboanhydrase F131C_C206S double mutant in complex with SA-2==		==Human carboanhydrase F131C_C206S double mutant in complex with SA-2==
-	<StructureSection load='5t71' size='340' side='right' caption='[[5t71]], [[Resolution\|resolution]] 1.30Å' scene=''>	+	<StructureSection load='5t71' size='340' side='right'caption='[[5t71]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5t71]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T71 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5T71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5t71]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T71 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75W:4-[(E)-diazenyl]benzene-1-sulfonamide'>75W</scene>, <scene name='pdbligand=HGB:4-(HYDROXYMERCURY)BENZOIC+ACID'>HGB</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vva\|2vva]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=75W:4-[(E)-diazenyl]benzene-1-sulfonamide'>75W</scene>, <scene name='pdbligand=HGB:4-(HYDROXYMERCURY)BENZOIC+ACID'>HGB</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t71 OCA], [https://pdbe.org/5t71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t71 RCSB], [https://www.ebi.ac.uk/pdbsum/5t71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t71 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5t71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t71 OCA], [~~http~~://pdbe.org/5t71 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5t71 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5t71 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5t71 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Defects in CA2 are the cause of osteopetrosis autosomal recessive type 3 (OPTB3) [MIM:[~~http~~://omim.org/entry/259730 259730]]; also known as osteopetrosis with renal tubular acidosis, carbonic anhydrase II deficiency syndrome, Guibaud-Vainsel syndrome or marble brain disease. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts. OPTB3 is associated with renal tubular acidosis, cerebral calcification (marble brain disease) and in some cases with mental retardation.<ref>PMID:1928091</ref> <ref>PMID:1542674</ref> <ref>PMID:8834238</ref> <ref>PMID:9143915</ref> <ref>PMID:15300855</ref>	+	[https://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN] Defects in CA2 are the cause of osteopetrosis autosomal recessive type 3 (OPTB3) [MIM:[https://omim.org/entry/259730 259730]; also known as osteopetrosis with renal tubular acidosis, carbonic anhydrase II deficiency syndrome, Guibaud-Vainsel syndrome or marble brain disease. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts. OPTB3 is associated with renal tubular acidosis, cerebral calcification (marble brain disease) and in some cases with mental retardation.<ref>PMID:1928091</ref> <ref>PMID:1542674</ref> <ref>PMID:8834238</ref> <ref>PMID:9143915</ref> <ref>PMID:15300855</ref>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.<ref>PMID:10550681</ref> <ref>PMID:11831900</ref>	+	[https://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.<ref>PMID:10550681</ref> <ref>PMID:11831900</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Optogenetics and photopharmacology are powerful approaches to investigating biochemical systems. While the former is based on genetically encoded photoreceptors that utilize abundant chromophores, the latter relies on synthetic photoswitches that are either freely diffusible or covalently attached to specific bioconjugation sites, which are often native or engineered cysteines. The identification of suitable cysteine sites and appropriate linkers for attachment is in general a lengthy and cumbersome process. Herein, we describe an in silico screening approach designed to propose a small number of optimal combinations. By applying this computational approach to human carbonic anhydrase and a set of three photochromic tethered ligands, the number of potential site-ligand combinations was narrowed from over 750 down to 6, which we then evaluated experimentally. Two of these six combinations resulted in light-responsive human Carbonic Anhydrases (LihCAs), which were characterized with enzymatic activity assays, mass spectrometry, and X-ray crystallography. Our study also provides insights into the reactivity of cysteines toward maleimides and the hydrolytic stability of the adducts obtained.	+

-	A predictive approach for the optical control of carbonic anhydrase II activity.,DuBay KH, Iwan K, Osorio-Planes L, Geissler PL, Groll M, Trauner D, Broichhagen J ACS Chem Biol. 2018 Jan 22. doi: 10.1021/acschembio.7b00862. PMID:29357237<ref>PMID:29357237</ref>	+	==See Also==
-		+	*[[Carbonic anhydrase 3D structures\|Carbonic anhydrase 3D structures]]
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class~~=~~"pdbe-citations 5t71" style~~=~~"background-color:#fffaf0;"></div>~~	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Carbonate dehydratase~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Human~~]]	+	[[Category: Large Structures]]
-	[[Category: Broichhagen, J]]	+	[[Category: Broichhagen J]]
-	[[Category: DuBay~~, K H~~]]	+	[[Category: DuBay KH]]
-	[[Category: Geissler, P]]	+	[[Category: Geissler P]]
-	[[Category: Groll, M]]	+	[[Category: Groll M]]
-	[[Category: Iwan, K]]	+	[[Category: Iwan K]]
-	[[Category: Osorio-Planes, L]]	+	[[Category: Osorio-Planes L]]
-	[[Category: Trauner, D]]	+	[[Category: Trauner D]]
-	~~[[Category: Azobenzene]]~~	+
-	~~[[Category: Carbonic anhydrase]]~~	+
-	~~[[Category: Computational screening]]~~	+
-	~~[[Category: Photochromic tethered ligand]]~~	+
-	~~[[Category: Photopharmacology]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:20, 22 February 2018

2018-02-22T08:20:26Z

←Older revision		Revision as of 08:20, 22 February 2018
Line 3:		Line 3:
	<StructureSection load='5t71' size='340' side='right' caption='[[5t71]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='5t71' size='340' side='right' caption='[[5t71]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5t71]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5t71]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T71 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75W:4-[(E)-diazenyl]benzene-1-sulfonamide'>75W</scene>, <scene name='pdbligand=HGB:4-(HYDROXYMERCURY)BENZOIC+ACID'>HGB</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75W:4-[(E)-diazenyl]benzene-1-sulfonamide'>75W</scene>, <scene name='pdbligand=HGB:4-(HYDROXYMERCURY)BENZOIC+ACID'>HGB</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vva\|2vva]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vva\|2vva]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t71 OCA], [http://pdbe.org/5t71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t71 RCSB], [http://www.ebi.ac.uk/pdbsum/5t71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t71 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t71 OCA], [http://pdbe.org/5t71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t71 RCSB], [http://www.ebi.ac.uk/pdbsum/5t71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t71 ProSAT]</span></td></tr>
Line 13:		Line 14:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.<ref>PMID:10550681</ref> <ref>PMID:11831900</ref>		[[http://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.<ref>PMID:10550681</ref> <ref>PMID:11831900</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Optogenetics and photopharmacology are powerful approaches to investigating biochemical systems. While the former is based on genetically encoded photoreceptors that utilize abundant chromophores, the latter relies on synthetic photoswitches that are either freely diffusible or covalently attached to specific bioconjugation sites, which are often native or engineered cysteines. The identification of suitable cysteine sites and appropriate linkers for attachment is in general a lengthy and cumbersome process. Herein, we describe an in silico screening approach designed to propose a small number of optimal combinations. By applying this computational approach to human carbonic anhydrase and a set of three photochromic tethered ligands, the number of potential site-ligand combinations was narrowed from over 750 down to 6, which we then evaluated experimentally. Two of these six combinations resulted in light-responsive human Carbonic Anhydrases (LihCAs), which were characterized with enzymatic activity assays, mass spectrometry, and X-ray crystallography. Our study also provides insights into the reactivity of cysteines toward maleimides and the hydrolytic stability of the adducts obtained.
		+
		+	A predictive approach for the optical control of carbonic anhydrase II activity.,DuBay KH, Iwan K, Osorio-Planes L, Geissler PL, Groll M, Trauner D, Broichhagen J ACS Chem Biol. 2018 Jan 22. doi: 10.1021/acschembio.7b00862. PMID:29357237<ref>PMID:29357237</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5t71" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 18:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Carbonate dehydratase]]		[[Category: Carbonate dehydratase]]
		+	[[Category: Human]]
	[[Category: Broichhagen, J]]		[[Category: Broichhagen, J]]
	[[Category: DuBay, K H]]		[[Category: DuBay, K H]]

OCA at 09:33, 13 September 2017

2017-09-13T09:33:21Z

←Older revision		Revision as of 09:33, 13 September 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5t71 ~~is ON HOLD until Paper Publication~~	+	==Human carboanhydrase F131C_C206S double mutant in complex with SA-2==
-		+	<StructureSection load='5t71' size='340' side='right' caption='[[5t71]], [[Resolution\|resolution]] 1.30Å' scene=''>
-	~~Authors~~: ~~DuBay, K~~.H., ~~Iwan~~, K., ~~Osorio~~-~~Planes~~, L., ~~Geissler~~, P., ~~Groll~~, M., ~~Trauner~~, D., ~~Broichhagen~~, J.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5t71]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T71 FirstGlance]. <br>
-	~~Description~~: ~~Human carboanhydrase F131C_C206S double mutant~~ in ~~complex with SA-2~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75W:4-[(E)-diazenyl]benzene-1-sulfonamide'>75W</scene>, <scene name='pdbligand=HGB:4-(HYDROXYMERCURY)BENZOIC+ACID'>HGB</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vva\|2vva]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t71 OCA], [http://pdbe.org/5t71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t71 RCSB], [http://www.ebi.ac.uk/pdbsum/5t71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t71 ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Defects in CA2 are the cause of osteopetrosis autosomal recessive type 3 (OPTB3) [MIM:[http://omim.org/entry/259730 259730]]; also known as osteopetrosis with renal tubular acidosis, carbonic anhydrase II deficiency syndrome, Guibaud-Vainsel syndrome or marble brain disease. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts. OPTB3 is associated with renal tubular acidosis, cerebral calcification (marble brain disease) and in some cases with mental retardation.<ref>PMID:1928091</ref> <ref>PMID:1542674</ref> <ref>PMID:8834238</ref> <ref>PMID:9143915</ref> <ref>PMID:15300855</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CAH2_HUMAN CAH2_HUMAN]] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.<ref>PMID:10550681</ref> <ref>PMID:11831900</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Carbonate dehydratase]]
	[[Category: Broichhagen, J]]		[[Category: Broichhagen, J]]
		+	[[Category: DuBay, K H]]
		+	[[Category: Geissler, P]]
		+	[[Category: Groll, M]]
	[[Category: Iwan, K]]		[[Category: Iwan, K]]
	[[Category: Osorio-Planes, L]]		[[Category: Osorio-Planes, L]]
	[[Category: Trauner, D]]		[[Category: Trauner, D]]
-	[[Category: ~~Dubay, K.H~~]]	+	[[Category: Azobenzene]]
-	[[Category: ~~Groll, M~~]]	+	[[Category: Carbonic anhydrase]]
-	[[Category: ~~Geissler, P~~]]	+	[[Category: Computational screening]]
		+	[[Category: Photochromic tethered ligand]]
		+	[[Category: Photopharmacology]]
		+	[[Category: Transferase]]

OCA at 13:23, 9 March 2017

2017-03-09T13:23:04Z

←Older revision		Revision as of 13:23, 9 March 2017
Line 7:		Line 7:
	Description: Human carboanhydrase F131C_C206S double mutant in complex with SA-2		Description: Human carboanhydrase F131C_C206S double mutant in complex with SA-2
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Osorio-Planes, L]]
-	[[Category: Trauner, D]]
-	[[Category: Geissler, P]]
	[[Category: Broichhagen, J]]		[[Category: Broichhagen, J]]
	[[Category: Iwan, K]]		[[Category: Iwan, K]]
		+	[[Category: Osorio-Planes, L]]
		+	[[Category: Trauner, D]]
	[[Category: Dubay, K.H]]		[[Category: Dubay, K.H]]
	[[Category: Groll, M]]		[[Category: Groll, M]]
		+	[[Category: Geissler, P]]

OCA: Protected "5t71" [edit=sysop:move=sysop]

2016-09-14T14:04:27Z

Protected "5t71" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:04, 14 September 2016

OCA: New page: '''Unreleased structure''' The entry 5t71 is ON HOLD until Paper Publication Authors: DuBay, K.H., Iwan, K., Osorio-Planes, L., Geissler, P., Groll, M., Trauner, D., Broichhagen, J. De...

2016-09-14T14:04:26Z

New page: '''Unreleased structure''' The entry 5t71 is ON HOLD until Paper Publication Authors: DuBay, K.H., Iwan, K., Osorio-Planes, L., Geissler, P., Groll, M., Trauner, D., Broichhagen, J. De...

New page

'''Unreleased structure'''

The entry 5t71 is ON HOLD until Paper Publication

Authors: DuBay, K.H., Iwan, K., Osorio-Planes, L., Geissler, P., Groll, M., Trauner, D., Broichhagen, J.

Description: Human carboanhydrase F131C_C206S double mutant in complex with SA-2
[[Category: Unreleased Structures]]
[[Category: Osorio-Planes, L]]
[[Category: Trauner, D]]
[[Category: Geissler, P]]
[[Category: Broichhagen, J]]
[[Category: Iwan, K]]
[[Category: Dubay, K.H]]
[[Category: Groll, M]]