5v51 - Revision history

OCA at 06:29, 17 April 2019

2019-04-17T06:29:14Z

←Older revision		Revision as of 06:29, 17 April 2019
Line 1:		Line 1:

	==Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min==		==Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min==
-	<StructureSection load='5v51' size='340' side='right' caption='[[5v51]], [[Resolution\|resolution]] 2.92Å' scene=''>	+	<StructureSection load='5v51' size='340' side='right'caption='[[5v51]], [[Resolution\|resolution]] 2.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5v51]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Crinipellis_perniciosa Crinipellis perniciosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V51 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5v51]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Crinipellis_perniciosa Crinipellis perniciosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V51 FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Crinipellis perniciosa]]		[[Category: Crinipellis perniciosa]]
		+	[[Category: Large Structures]]
	[[Category: Asojo, O]]		[[Category: Asojo, O]]
	[[Category: Luo, Z]]		[[Category: Luo, Z]]

OCA at 08:14, 17 January 2018

2018-01-17T08:14:47Z

←Older revision		Revision as of 08:14, 17 January 2018
Line 3:		Line 3:
	<StructureSection load='5v51' size='340' side='right' caption='[[5v51]], [[Resolution\|resolution]] 2.92Å' scene=''>		<StructureSection load='5v51' size='340' side='right' caption='[[5v51]], [[Resolution\|resolution]] 2.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5v51]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V51 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5v51]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Crinipellis_perniciosa Crinipellis perniciosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V51 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEY:SELENOUREA'>SEY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEY:SELENOUREA'>SEY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5v50\|5v50]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5v50\|5v50]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PR-1i ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=153609 Crinipellis perniciosa])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v51 OCA], [http://pdbe.org/5v51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v51 RCSB], [http://www.ebi.ac.uk/pdbsum/5v51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v51 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v51 OCA], [http://pdbe.org/5v51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v51 RCSB], [http://www.ebi.ac.uk/pdbsum/5v51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v51 ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Crinipellis perniciosa]]
	[[Category: Asojo, O]]		[[Category: Asojo, O]]
	[[Category: Luo, Z]]		[[Category: Luo, Z]]

OCA at 04:02, 30 August 2017

2017-08-30T04:02:03Z

←Older revision		Revision as of 04:02, 30 August 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5v51 is ~~ON HOLD until Paper~~ Publication	+	==Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min==
		+	<StructureSection load='5v51' size='340' side='right' caption='[[5v51]], [[Resolution\|resolution]] 2.92Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5v51]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V51 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEY:SELENOUREA'>SEY</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5v50\|5v50]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v51 OCA], [http://pdbe.org/5v51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v51 RCSB], [http://www.ebi.ac.uk/pdbsum/5v51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v51 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The pathogenic fungi Moniliophthora perniciosa causes Witches' Broom Disease (WBD) of cacao. The structure of MpPR-1i, a protein expressed by M. perniciosa when it infects cacao, are presented. This is the first reported de novo structure determined by single-wavelength anomalous dispersion phasing upon soaking with selenourea. Each monomer has flexible loop regions linking the core alpha-beta-alpha sandwich topology that comprise ~50% of the structure, making it difficult to generate an accurate homology model of the protein. MpPR-1i is monomeric in solution but is packed as a high ~70% solvent content, crystallographic heptamer. The greatest conformational flexibility between monomers is found in loops exposed to the solvent channel that connect the two longest strands. MpPR-1i lacks the conserved CAP tetrad and is incapable of binding divalent cations. MpPR-1i has the ability to bind lipids, which may have roles in its infection of cacao. These lipids likely bind in the palmitate binding cavity as observed in tablysin-15, since MpPR-1i binds palmitate with comparable affinity as tablysin-15. Further studies are required to clarify the possible roles and underlying mechanisms of neutral lipid binding, as well as their effects on the pathogenesis of M. perniciosa so as to develop new interventions for WBD.

-	~~Authors: Luo~~, Z., ~~Asojo~~, O.	+	Crystal Structure of MpPR-1i, a SCP/TAPS protein from Moniliophthora perniciosa, the fungus that causes Witches' Broom Disease of Cacao.,Baroni RM, Luo Z, Darwiche R, Hudspeth EM, Schneiter R, Pereira GAG, Mondego JMC, Asojo OA Sci Rep. 2017 Aug 10;7(1):7818. doi: 10.1038/s41598-017-07887-1. PMID:28798297<ref>PMID:28798297</ref>

-	~~Description: Crystal Structure~~ of ~~MpPR-1i Soaked with Selenourea for 10 min~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5v51" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Asojo, O]]		[[Category: Asojo, O]]
	[[Category: Luo, Z]]		[[Category: Luo, Z]]
		+	[[Category: Cacao infection]]
		+	[[Category: Lipid binding protein]]
		+	[[Category: Pathogenesis-related protein 1]]
		+	[[Category: Selenourea]]

OCA: Protected "5v51" [edit=sysop:move=sysop]

2017-04-05T11:36:17Z

Protected "5v51" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:36, 5 April 2017

OCA: New page: '''Unreleased structure''' The entry 5v51 is ON HOLD until Paper Publication Authors: Luo, Z., Asojo, O. Description: Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min [[C...

2017-04-05T11:36:15Z

New page: '''Unreleased structure''' The entry 5v51 is ON HOLD until Paper Publication Authors: Luo, Z., Asojo, O. Description: Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min [[C...

New page

'''Unreleased structure'''

The entry 5v51 is ON HOLD until Paper Publication

Authors: Luo, Z., Asojo, O.

Description: Crystal Structure of MpPR-1i Soaked with Selenourea for 10 min
[[Category: Unreleased Structures]]
[[Category: Asojo, O]]
[[Category: Luo, Z]]