5vj8 - Revision history

OCA at 10:28, 14 June 2023

2023-06-14T10:28:20Z

←Older revision		Revision as of 10:28, 14 June 2023
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	==Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc==		==Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc==
-	<StructureSection load='5vj8' size='340' side='right'caption='[[5vj8~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='5vj8' size='340' side='right'caption='[[5vj8]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus~~ pestis~~" (lehmann and neumann 1896) migula 1900~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n2l\|2n2l]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [https://pdbe.org/5vj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [https://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AVJ24_14645, AVO31_14870 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [~~http~~://pdbe.org/5vj8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A5P8YI02_YERPE A0A5P8YI02_YERPE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Dutta, S K~~]]	+	[[Category: Yersinia pestis]]
-	[[Category: ~~Marassi, F M~~]]	+	[[Category: Dutta SK]]
-	[[Category: ~~Yong, Y~~]]	+	[[Category: Marassi FM]]
-	[[Category: ~~Adhesion invasion locus]]~~	+	[[Category: Yong Y]]
-	~~[[Category: Beta-barrel]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Nanodisc~~]]	+

OCA at 09:35, 1 January 2020

2020-01-01T09:35:31Z

←Older revision		Revision as of 09:35, 1 January 2020
Line 1:		Line 1:

	==Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc==		==Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc==
-	<StructureSection load='5vj8' size='340' side='right' caption='[[5vj8]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='5vj8' size='340' side='right'caption='[[5vj8]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Dutta, S K]]		[[Category: Dutta, S K]]
	[[Category: Marassi, F M]]		[[Category: Marassi, F M]]

OCA at 20:47, 2 December 2018

2018-12-02T20:47:12Z

←Older revision		Revision as of 20:47, 2 December 2018
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [http://pdbe.org/5vj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [http://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [http://pdbe.org/5vj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [http://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Yersinia pestis the causative agent of plague, is highly pathogenic and poses very high risk to public health. The outer membrane protein Ail (Adhesion invasion locus) is one of the most highly expressed proteins on the cell surface of Y. pestis, and a major target for the development of medical countermeasures. Ail is essential for microbial virulence and is critical for promoting the survival of Y. pestis in serum. Structures of Ail have been determined by X-ray diffraction and solution NMR spectroscopy, but the protein's activity is influenced by the detergents in these samples, underscoring the importance of the surrounding environment for structure-activity studies. Here we describe the backbone structure of Ail, determined in lipid bilayer nanodiscs, using solution NMR spectroscopy. We also present solid-state NMR data obtained for Ail in membranes containing lipopolysaccharide (LPS), a major component of the bacterial outer membranes. The protein in lipid bilayers, adopts the same eight-stranded beta-barrel fold observed in the crystalline and micellar states. The membrane composition, however, appears to have a marked effect on protein dynamics, with LPS enhancing conformational order and slowing down the (15)N transverse relaxation rate. The results provide information about the way in which an outer membrane protein inserts and functions in the bacterial membrane.
		+
		+	Structural Insights into the Yersinia pestis Outer Membrane Protein Ail in Lipid Bilayers.,Dutta SK, Yao Y, Marassi FM J Phys Chem B. 2017 Aug 17;121(32):7561-7570. doi: 10.1021/acs.jpcb.7b03941. Epub, 2017 Aug 4. PMID:28726410<ref>PMID:28726410</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5vj8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 20:00, 15 November 2017

2017-11-15T20:00:12Z

←Older revision		Revision as of 20:00, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='5vj8' size='340' side='right' caption='[[5vj8]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='5vj8' size='340' side='right' caption='[[5vj8]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n2l\|2n2l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n2l\|2n2l]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AVJ24_14645, AVO31_14870 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [http://pdbe.org/5vj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [http://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [http://pdbe.org/5vj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [http://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 15:51, 17 May 2017

2017-05-17T15:51:14Z

←Older revision		Revision as of 15:51, 17 May 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5vj8 is ~~ON HOLD~~	+	==Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc==
-		+	<StructureSection load='5vj8' size='340' side='right' caption='[[5vj8]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
-	~~Authors~~: ~~Dutta~~, S.K., ~~Yong~~, Y., ~~Marassi~~, F.M.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5vj8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VJ8 FirstGlance]. <br>
-	~~Description: Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n2l\|2n2l]]</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vj8 OCA], [http://pdbe.org/5vj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vj8 RCSB], [http://www.ebi.ac.uk/pdbsum/5vj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vj8 ProSAT]</span></td></tr>
-	[[Category: ~~Dutta~~, ~~S.K~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Dutta, S K]]
		+	[[Category: Marassi, F M]]
	[[Category: Yong, Y]]		[[Category: Yong, Y]]
-	[[Category: ~~Marassi, F.M~~]]	+	[[Category: Adhesion invasion locus]]
		+	[[Category: Beta-barrel]]
		+	[[Category: Membrane protein]]
		+	[[Category: Nanodisc]]

OCA: Protected "5vj8" [edit=sysop:move=sysop]

2017-04-27T12:20:50Z

Protected "5vj8" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:20, 27 April 2017

OCA: New page: '''Unreleased structure''' The entry 5vj8 is ON HOLD Authors: Dutta, S.K., Yong, Y., Marassi, F.M. Description: Backbone structure of the Yersinia pestis outer membrane protein Ail in ...

2017-04-27T12:20:49Z

New page: '''Unreleased structure''' The entry 5vj8 is ON HOLD Authors: Dutta, S.K., Yong, Y., Marassi, F.M. Description: Backbone structure of the Yersinia pestis outer membrane protein Ail in ...

New page

'''Unreleased structure'''

The entry 5vj8 is ON HOLD

Authors: Dutta, S.K., Yong, Y., Marassi, F.M.

Description: Backbone structure of the Yersinia pestis outer membrane protein Ail in phospholipid bilayer nanodisc
[[Category: Unreleased Structures]]
[[Category: Dutta, S.K]]
[[Category: Yong, Y]]
[[Category: Marassi, F.M]]