5wt7 - Revision history

OCA at 10:29, 14 June 2023

2023-06-14T10:29:56Z

←Older revision		Revision as of 10:29, 14 June 2023
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	==FAS1-IV domain of Human Periostin==		==FAS1-IV domain of Human Periostin==
-	<StructureSection load='5wt7' size='340' side='right' caption='[[5wt7~~]], [[NMR_Ensembles_of_Models \| 23 NMR models~~]]' scene=''>	+	<StructureSection load='5wt7' size='340' side='right'caption='[[5wt7]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wt7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WT7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wt7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WT7 FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POSTN, OSF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt7 OCA], [https://pdbe.org/5wt7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wt7 RCSB], [https://www.ebi.ac.uk/pdbsum/5wt7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt7 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt7 OCA], [~~http~~://pdbe.org/5wt7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wt7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wt7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt7 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/POSTN_HUMAN POSTN_HUMAN]] Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).[UniProtKB:Q62009]<ref>PMID:12235007</ref>	+	[https://www.uniprot.org/uniprot/POSTN_HUMAN POSTN_HUMAN] Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).[UniProtKB:Q62009]<ref>PMID:12235007</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Lee, C W~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Yun, H~~]]	+	[[Category: Lee CW]]
-	[[Category: ~~Cancer]]~~	+	[[Category: Yun H]]
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Chronic allergic inflammation disease]]~~	+
-	~~[[Category: Integrin]]~~	+
-	~~[[Category: Periostin~~]]	+

OCA at 06:52, 4 April 2018

2018-04-04T06:52:03Z

←Older revision		Revision as of 06:52, 4 April 2018
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	<StructureSection load='5wt7' size='340' side='right' caption='[[5wt7]], [[NMR_Ensembles_of_Models \| 23 NMR models]]' scene=''>		<StructureSection load='5wt7' size='340' side='right' caption='[[5wt7]], [[NMR_Ensembles_of_Models \| 23 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wt7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wt7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt7 OCA], [http://pdbe.org/5wt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt7 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt7 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POSTN, OSF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt7 OCA], [http://pdbe.org/5wt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt7 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Lee, C W]]		[[Category: Lee, C W]]
	[[Category: Yun, H]]		[[Category: Yun, H]]

OCA at 07:00, 13 December 2017

2017-12-13T07:00:12Z

←Older revision		Revision as of 07:00, 13 December 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5wt7 is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==FAS1-IV domain of Human Periostin==
		+	<StructureSection load='5wt7' size='340' side='right' caption='[[5wt7]], [[NMR_Ensembles_of_Models \| 23 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5wt7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT7 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt7 OCA], [http://pdbe.org/5wt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt7 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt7 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/POSTN_HUMAN POSTN_HUMAN]] Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).[UniProtKB:Q62009]<ref>PMID:12235007</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Periostin, an extracellular matrix protein, is secreted by fibroblasts and is overexpressed in various types of cancers. The four internal repeat fasciclin 1 (FAS1) domains of human periostin play crucial roles in promoting tumor metastasis and progression via interaction with cell surface integrins. Among four FAS1 domains of human periostin, the fourth FAS1 domain (FAS1-IV) was prepared for NMR study, since only FAS1-IV was highly soluble, and showed a well-dispersed 2D (1)H-(15)N HSQC spectrum. Here, we report nearly complete backbone and side chain resonance assignments and a secondary structural analysis of the FAS1-IV domain as first steps toward the structure determination of FAS1-IV of human periostin.

-	~~Authors: Yun,~~ H., Lee, C.W.	+	(1)H, (13)C, and (15)N resonance assignments of FAS1-IV domain of human periostin, a component of extracellular matrix proteins.,Yun H, Kim EH, Lee CW Biomol NMR Assign. 2017 Oct 31. pii: 10.1007/s12104-017-9786-z. doi:, 10.1007/s12104-017-9786-z. PMID:29086898<ref>PMID:29086898</ref>

-	~~Description: FAS1-IV domain~~ of ~~Human Periostin~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5wt7" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Lee, C W]]
	[[Category: Yun, H]]		[[Category: Yun, H]]
-	[[Category: ~~Lee, C.W~~]]	+	[[Category: Cancer]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Chronic allergic inflammation disease]]
		+	[[Category: Integrin]]
		+	[[Category: Periostin]]

OCA at 15:07, 27 September 2017

2017-09-27T15:07:10Z

←Older revision		Revision as of 15:07, 27 September 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5wt7 is ON HOLD	+	The entry 5wt7 is ON HOLD until Paper Publication

	Authors: Yun, H., Lee, C.W.		Authors: Yun, H., Lee, C.W.

OCA: Protected "5wt7" [edit=sysop:move=sysop]

2016-12-22T20:40:59Z

Protected "5wt7" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:40, 22 December 2016

OCA: New page: '''Unreleased structure''' The entry 5wt7 is ON HOLD Authors: Yun, H., Lee, C.W. Description: FAS1-IV domain of Human Periostin Category: Unreleased Structures Category: Yun, H...

2016-12-22T20:40:58Z

New page: '''Unreleased structure''' The entry 5wt7 is ON HOLD Authors: Yun, H., Lee, C.W. Description: FAS1-IV domain of Human Periostin Category: Unreleased Structures Category: Yun, H...

New page

'''Unreleased structure'''

The entry 5wt7 is ON HOLD

Authors: Yun, H., Lee, C.W.

Description: FAS1-IV domain of Human Periostin
[[Category: Unreleased Structures]]
[[Category: Yun, H]]
[[Category: Lee, C.W]]