OCA at 11:26, 6 November 2017

2017-11-06T11:26:57Z

←Older revision		Revision as of 11:26, 6 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5wxm is ~~ON HOLD~~ ~~until Jan 07 2019~~	+	==Crystal structure of the Imp3 and Mpp10 complex==
		+	<StructureSection load='5wxm' size='340' side='right' caption='[[5wxm]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5wxm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WXM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WXM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IMP3, YHR148W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), MPP10, YJR002W, J1411, YJR83.5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wxm OCA], [http://pdbe.org/5wxm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wxm RCSB], [http://www.ebi.ac.uk/pdbsum/5wxm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wxm ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IMP3_YEAST IMP3_YEAST]] Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing.<ref>PMID:10409734</ref> <ref>PMID:15489263</ref> [[http://www.uniprot.org/uniprot/MPP10_YEAST MPP10_YEAST]] Involved in nucleolar processing of pre-18S ribosomal RNA. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing.<ref>PMID:15489263</ref> <ref>PMID:9315638</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Eukaryotic small ribosomal subunits are first assembled into 90S pre-ribosomes. The complete 90S is a gigantic complex with a molecular mass of approximately five megadaltons. Here, we report the nearly complete architecture of Saccharomyces cerevisiae 90S determined from three cryo-electron microscopy single particle reconstructions at 4.5 to 8.7 angstrom resolution. The majority of the density maps were modeled and assigned to specific RNA and protein components. The nascent ribosome is assembled into isolated native-like substructures that are stabilized by abundant assembly factors. The 5' external transcribed spacer and U3 snoRNA nucleate a large subcomplex that scaffolds the nascent ribosome. U3 binds four sites of pre-rRNA, including a novel site on helix 27 but not the 3' side of the central pseudoknot, and crucially organizes the 90S structure. The 90S model provides significant insight into the principle of small subunit assembly and the function of assembly factors.

-	~~Authors: Ye, K~~., ~~Zheng~~, S.	+	Molecular architecture of the 90S small subunit pre-ribosome.,Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye K Elife. 2017 Feb 28;6. pii: e22086. doi: 10.7554/eLife.22086. PMID:28244370<ref>PMID:28244370</ref>

-	~~Description: Crystal structure~~ of the ~~Imp3 and Mpp10 complex~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5wxm" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Baker's yeast]]
	[[Category: Ye, K]]		[[Category: Ye, K]]
	[[Category: Zheng, S]]		[[Category: Zheng, S]]
		+	[[Category: Components of 90s preribosome]]
		+	[[Category: Protein complex]]
		+	[[Category: Ribosomal protein]]

OCA at 19:57, 15 March 2017

2017-03-15T19:57:45Z

←Older revision		Revision as of 19:57, 15 March 2017
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	Description: Crystal structure of the Imp3 and Mpp10 complex		Description: Crystal structure of the Imp3 and Mpp10 complex
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Zheng, S]]
	[[Category: Ye, K]]		[[Category: Ye, K]]
		+	[[Category: Zheng, S]]

OCA at 22:33, 25 January 2017

2017-01-25T22:33:27Z

←Older revision		Revision as of 22:33, 25 January 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5wxm is ON HOLD	+	The entry 5wxm is ON HOLD until Jan 07 2019

	Authors: Ye, K., Zheng, S.		Authors: Ye, K., Zheng, S.

OCA: Protected "5wxm" [edit=sysop:move=sysop]

2017-01-18T15:19:33Z

Protected "5wxm" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:19, 18 January 2017

OCA: New page: '''Unreleased structure''' The entry 5wxm is ON HOLD Authors: Ye, K., Zheng, S. Description: Crystal structure of the Imp3 and Mpp10 complex Category: Unreleased Structures [[Categ...

2017-01-18T15:19:32Z

New page: '''Unreleased structure''' The entry 5wxm is ON HOLD Authors: Ye, K., Zheng, S. Description: Crystal structure of the Imp3 and Mpp10 complex Category: Unreleased Structures [[Categ...

New page

'''Unreleased structure'''

The entry 5wxm is ON HOLD

Authors: Ye, K., Zheng, S.

Description: Crystal structure of the Imp3 and Mpp10 complex
[[Category: Unreleased Structures]]
[[Category: Zheng, S]]
[[Category: Ye, K]]

5wxm - Revision history

OCA at 11:26, 6 November 2017

OCA at 19:57, 15 March 2017

OCA at 22:33, 25 January 2017

OCA: Protected "5wxm" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 5wxm is ON HOLD Authors: Ye, K., Zheng, S. Description: Crystal structure of the Imp3 and Mpp10 complex Category: Unreleased Structures [[Categ...