5xc5 - Revision history

OCA at 07:59, 22 November 2023

2023-11-22T07:59:17Z

←Older revision		Revision as of 07:59, 22 November 2023
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	<StructureSection load='5xc5' size='340' side='right'caption='[[5xc5]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='5xc5' size='340' side='right'caption='[[5xc5]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xc5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XC5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XC5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_polyphaga_mimivirus Acanthamoeba polyphaga mimivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XC5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.398Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5xc3\|5xc3]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xc5 OCA], [~~http~~://pdbe.org/5xc5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xc5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xc5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xc5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xc5 OCA], [https://pdbe.org/5xc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xc5 RCSB], [https://www.ebi.ac.uk/pdbsum/5xc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xc5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RABL_MIMIV RABL_MIMIV]] May be involved in protein transport.	+	[https://www.uniprot.org/uniprot/RABL_MIMIV RABL_MIMIV] May be involved in protein transport.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Large Structures]]
-	[[Category: Kim, S J]]
-	[[Category: Ku, B]]
-	[[Category: You, J A]]
	[[Category: Acanthamoeba polyphaga mimivirus]]		[[Category: Acanthamoeba polyphaga mimivirus]]
-	[[Category: ~~Protein transport~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Rab gtpase~~]]	+	[[Category: Kim SJ]]
-	[[Category: ~~Vesicle trafficking~~]]	+	[[Category: Ku B]]
		+	[[Category: You JA]]

OCA at 06:45, 14 October 2020

2020-10-14T06:45:54Z

←Older revision		Revision as of 06:45, 14 October 2020
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	==Crystal structure of Acanthamoeba polyphaga mimivirus Rab GTPase in complex with GTP==		==Crystal structure of Acanthamoeba polyphaga mimivirus Rab GTPase in complex with GTP==
-	<StructureSection load='5xc5' size='340' side='right' caption='[[5xc5]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='5xc5' size='340' side='right'caption='[[5xc5]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xc5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XC5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XC5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xc5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XC5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XC5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5xc3\|5xc3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5xc3\|5xc3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xc5 OCA], [http://pdbe.org/5xc5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xc5 RCSB], [http://www.ebi.ac.uk/pdbsum/5xc5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xc5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xc5 OCA], [http://pdbe.org/5xc5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xc5 RCSB], [http://www.ebi.ac.uk/pdbsum/5xc5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xc5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Kim, S J]]		[[Category: Kim, S J]]
	[[Category: Ku, B]]		[[Category: Ku, B]]

OCA at 06:54, 25 October 2017

2017-10-25T06:54:48Z

←Older revision		Revision as of 06:54, 25 October 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5xc5 is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of Acanthamoeba polyphaga mimivirus Rab GTPase in complex with GTP==
		+	<StructureSection load='5xc5' size='340' side='right' caption='[[5xc5]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xc5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XC5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XC5 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5xc3\|5xc3]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xc5 OCA], [http://pdbe.org/5xc5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xc5 RCSB], [http://www.ebi.ac.uk/pdbsum/5xc5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xc5 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RABL_MIMIV RABL_MIMIV]] May be involved in protein transport.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Acanthamoeba polyphaga mimivirus (APMV) is a member of the family of giant viruses, harboring a 1,200 kbp genome within its 700 nm-diameter viral particle. The R214 gene of the APMV genome was recently shown to encode a homologue of the Rab GTPases, molecular switch proteins known to play a pivotal role in the regulation of membrane trafficking that were considered to exist only in eukaryotes. Herein, we report the first crystal structures of GDP- and GTP-bound forms of APMV Rab GTPase, both of which were determined at high resolution. An in-depth structural comparison of APMV Rab with each other and with mammalian Rab homologues led to an atomic-level elucidation of the inactive-active conformational change upon GDP/GTP exchange. APMV Rab GTPase exhibited considerable structural similarity to human Rab5, as previously predicted based on its amino acid sequence. However, it also contains unique structural features differentiating it from mammalian homologues, such as the functional substitution of a phenylalanine residue for the stabilization of the nucleotide's guanine base.

-	~~Authors~~:	+	Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase.,Ku B, You JA, Oh KJ, Yun HY, Lee HS, Shin HC, Jung J, Shin YB, Kim SJ Arch Virol. 2017 Nov;162(11):3407-3416. doi: 10.1007/s00705-017-3510-2. Epub 2017, Aug 4. PMID:28779233<ref>PMID:28779233</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5xc5" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kim, S J]]
		+	[[Category: Ku, B]]
		+	[[Category: You, J A]]
		+	[[Category: Acanthamoeba polyphaga mimivirus]]
		+	[[Category: Protein transport]]
		+	[[Category: Rab gtpase]]
		+	[[Category: Vesicle trafficking]]

OCA at 12:02, 4 May 2017

2017-05-04T12:02:51Z

←Older revision		Revision as of 12:02, 4 May 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xc5 is ON HOLD	+	The entry 5xc5 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5xc5" [edit=sysop:move=sysop]

2017-04-05T12:28:34Z

Protected "5xc5" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:28, 5 April 2017

OCA: New page: '''Unreleased structure''' The entry 5xc5 is ON HOLD Authors: Description: Category: Unreleased Structures

2017-04-05T12:28:33Z

New page: '''Unreleased structure''' The entry 5xc5 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5xc5 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]