5xi3 - Revision history

OCA at 10:18, 27 March 2024

2024-03-27T10:18:41Z

←Older revision		Revision as of 10:18, 27 March 2024
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	<StructureSection load='5xi3' size='340' side='right'caption='[[5xi3]], [[Resolution\|resolution]] 1.67Å' scene=''>		<StructureSection load='5xi3' size='340' side='right'caption='[[5xi3]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xi3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XI3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xi3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XI3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8F6:(3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{R})-1-phenylethyl]amino]-3~{H}-quinoxalin-2-one'>8F6</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.674Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi3 OCA], [~~http~~://pdbe.org/5xi3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xi3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xi3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi3 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8F6:(3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{R})-1-phenylethyl]amino]-3~{H}-quinoxalin-2-one'>8F6</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi3 OCA], [https://pdbe.org/5xi3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xi3 RCSB], [https://www.ebi.ac.uk/pdbsum/5xi3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi3 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).	+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cao, D]]	+	[[Category: Cao D]]
-	[[Category: Li, Y]]	+	[[Category: Li Y]]
-	[[Category: Xiong, B]]	+	[[Category: Xiong B]]
-	~~[[Category: Chromatin regulator]]~~	+
-	~~[[Category: Transcription-inhibitor complex~~]]	+

OCA at 06:50, 14 October 2020

2020-10-14T06:50:23Z

←Older revision		Revision as of 06:50, 14 October 2020
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	==BRD4 bound with compound Bdi3==		==BRD4 bound with compound Bdi3==
-	<StructureSection load='5xi3' size='340' side='right' caption='[[5xi3]], [[Resolution\|resolution]] 1.67Å' scene=''>	+	<StructureSection load='5xi3' size='340' side='right'caption='[[5xi3]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xi3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XI3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xi3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XI3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8F6:(3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{R})-1-phenylethyl]amino]-3~{H}-quinoxalin-2-one'>8F6</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8F6:(3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{R})-1-phenylethyl]amino]-3~{H}-quinoxalin-2-one'>8F6</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi3 OCA], [http://pdbe.org/5xi3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xi3 RCSB], [http://www.ebi.ac.uk/pdbsum/5xi3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi3 OCA], [http://pdbe.org/5xi3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xi3 RCSB], [http://www.ebi.ac.uk/pdbsum/5xi3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi3 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).		[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+
		+	==See Also==
		+	*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Cao, D]]		[[Category: Cao, D]]
	[[Category: Li, Y]]		[[Category: Li, Y]]

OCA at 08:03, 2 May 2018

2018-05-02T08:03:21Z

←Older revision		Revision as of 08:03, 2 May 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5xi3 is ~~ON HOLD until May 03 2019~~	+	==BRD4 bound with compound Bdi3==
-		+	<StructureSection load='5xi3' size='340' side='right' caption='[[5xi3]], [[Resolution\|resolution]] 1.67Å' scene=''>
-	~~Authors~~: ~~Xiong~~, B., ~~Cao~~, D., Li, Y.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5xi3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XI3 FirstGlance]. <br>
-	~~Description~~: BRD4 ~~bound~~ with ~~compound Bdi3~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8F6:(3~{R})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{R})-1-phenylethyl]amino]-3~{H}-quinoxalin-2-one'>8F6</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi3 OCA], [http://pdbe.org/5xi3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xi3 RCSB], [http://www.ebi.ac.uk/pdbsum/5xi3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi3 ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cao, D]]		[[Category: Cao, D]]
		+	[[Category: Li, Y]]
	[[Category: Xiong, B]]		[[Category: Xiong, B]]
-	[[Category: ~~Li, Y~~]]	+	[[Category: Chromatin regulator]]
		+	[[Category: Transcription-inhibitor complex]]

OCA at 03:47, 25 April 2018

2018-04-25T03:47:56Z

←Older revision		Revision as of 03:47, 25 April 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xi3 is ON HOLD until ~~Apr 25~~ 2019	+	The entry 5xi3 is ON HOLD until May 03 2019

	Authors: Xiong, B., Cao, D., Li, Y.		Authors: Xiong, B., Cao, D., Li, Y.

OCA at 06:23, 8 November 2017

2017-11-08T06:23:53Z

←Older revision		Revision as of 06:23, 8 November 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xi3 is ON HOLD	+	The entry 5xi3 is ON HOLD until Apr 25 2019

	Authors: Xiong, B., Cao, D., Li, Y.		Authors: Xiong, B., Cao, D., Li, Y.
Line 7:		Line 7:
	Description: BRD4 bound with compound Bdi3		Description: BRD4 bound with compound Bdi3
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Li, Y]]
-	[[Category: Xiong, B]]
	[[Category: Cao, D]]		[[Category: Cao, D]]
		+	[[Category: Xiong, B]]
		+	[[Category: Li, Y]]

OCA at 15:29, 27 September 2017

2017-09-27T15:29:14Z

←Older revision		Revision as of 15:29, 27 September 2017
Line 3:		Line 3:
	The entry 5xi3 is ON HOLD		The entry 5xi3 is ON HOLD

-	Authors: ~~Bing~~ Xiong, ~~Danyan~~ Cao, ~~Yanlian~~ Li	+	Authors: Xiong, B., Cao, D., Li, Y.

	Description: BRD4 bound with compound Bdi3		Description: BRD4 bound with compound Bdi3
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Bing~~ Xiong, ~~Danyan~~ Cao, ~~Yanlian Li~~]]	+	[[Category: Li, Y]]
		+	[[Category: Xiong, B]]
		+	[[Category: Cao, D]]

OCA: Protected "5xi3" [edit=sysop:move=sysop]

2017-05-04T12:13:51Z

Protected "5xi3" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:13, 4 May 2017

OCA: New page: '''Unreleased structure''' The entry 5xi3 is ON HOLD Authors: Bing Xiong, Danyan Cao, Yanlian Li Description: BRD4 bound with compound Bdi3 Category: Unreleased Structures [[Catego...

2017-05-04T12:13:49Z

New page: '''Unreleased structure''' The entry 5xi3 is ON HOLD Authors: Bing Xiong, Danyan Cao, Yanlian Li Description: BRD4 bound with compound Bdi3 Category: Unreleased Structures [[Catego...

New page

'''Unreleased structure'''

The entry 5xi3 is ON HOLD

Authors: Bing Xiong, Danyan Cao, Yanlian Li

Description: BRD4 bound with compound Bdi3
[[Category: Unreleased Structures]]
[[Category: Bing Xiong, Danyan Cao, Yanlian Li]]