5xkb - Revision history

OCA at 10:18, 27 March 2024

2024-03-27T10:18:54Z

←Older revision		Revision as of 10:18, 27 March 2024
Line 3:		Line 3:
	<StructureSection load='5xkb' size='340' side='right'caption='[[5xkb]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5xkb' size='340' side='right'caption='[[5xkb]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xkb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XKB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XKB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xkb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XKB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WVP:5,15-Bisethynyl-10,20-diphenylporphyrin+containing+FE'>WVP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xkb OCA], [~~http~~://pdbe.org/5xkb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xkb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xkb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xkb ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WVP:5,15-Bisethynyl-10,20-diphenylporphyrin+containing+FE'>WVP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xkb OCA], [https://pdbe.org/5xkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xkb RCSB], [https://www.ebi.ac.uk/pdbsum/5xkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xkb ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/G3XD33_PSEAE G3XD33_PSEAE]
-	Iron(III)-5,15-diphenylporphyrin and several derivatives were accommodated by HasA, a heme acquisition protein secreted by Pseudomonas aeruginosa, despite possessing bulky substituents at the meso position of the porphyrin. Crystal structure analysis revealed that the two phenyl groups at the meso positions of porphyrin extend outside HasA. It was shown that the growth of P. aeruginosa was inhibited in the presence of HasA coordinating the synthetic porphyrins under iron-limiting conditions, and that the structure of the synthetic porphyrins greatly affects the inhibition efficiency.	+
-		+
-	Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group.,Uehara H, Shisaka Y, Nishimura T, Sugimoto H, Shiro Y, Miyake Y, Shinokubo H, Watanabe Y, Shoji O Angew Chem Int Ed Engl. 2017 Nov 27;56(48):~~15279-15283. doi:, 10.1002~~/~~anie.201707212. Epub 2017 Oct 9. PMID:28921809<ref>PMID:28921809<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 5xkb" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Shiro, Y]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Shoji, O]]	+	[[Category: Shiro Y]]
-	[[Category: Sugimoto, H]]	+	[[Category: Shoji O]]
-	[[Category: Uehara, H]]	+	[[Category: Sugimoto H]]
-	[[Category: Watanabe, Y]]	+	[[Category: Uehara H]]
-	~~[[Category: Heme acquisition protein]]~~	+	[[Category: Watanabe Y]]
-	~~[[Category: Transport protein~~]]	+

OCA at 06:53, 14 October 2020

2020-10-14T06:53:04Z

←Older revision		Revision as of 06:53, 14 October 2020
Line 1:		Line 1:

	==Crystal Structure of HasAp with Fe-5,15-bisethynyl-10,20-diphenylporphyrin==		==Crystal Structure of HasAp with Fe-5,15-bisethynyl-10,20-diphenylporphyrin==
-	<StructureSection load='5xkb' size='340' side='right' caption='[[5xkb]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5xkb' size='340' side='right'caption='[[5xkb]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xkb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XKB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XKB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xkb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XKB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XKB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WVP:5,15-Bisethynyl-10,20-diphenylporphyrin+containing+FE'>WVP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WVP:5,15-Bisethynyl-10,20-diphenylporphyrin+containing+FE'>WVP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xkb OCA], [http://pdbe.org/5xkb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xkb RCSB], [http://www.ebi.ac.uk/pdbsum/5xkb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xkb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xkb OCA], [http://pdbe.org/5xkb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xkb RCSB], [http://www.ebi.ac.uk/pdbsum/5xkb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xkb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Shiro, Y]]		[[Category: Shiro, Y]]
	[[Category: Shoji, O]]		[[Category: Shoji, O]]

OCA at 07:20, 6 December 2017

2017-12-06T07:20:59Z

←Older revision		Revision as of 07:20, 6 December 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5xkb is ~~ON HOLD~~	+	==Crystal Structure of HasAp with Fe-5,15-bisethynyl-10,20-diphenylporphyrin==
		+	<StructureSection load='5xkb' size='340' side='right' caption='[[5xkb]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xkb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XKB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XKB FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WVP:5,15-Bisethynyl-10,20-diphenylporphyrin+containing+FE'>WVP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xkb OCA], [http://pdbe.org/5xkb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xkb RCSB], [http://www.ebi.ac.uk/pdbsum/5xkb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xkb ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Iron(III)-5,15-diphenylporphyrin and several derivatives were accommodated by HasA, a heme acquisition protein secreted by Pseudomonas aeruginosa, despite possessing bulky substituents at the meso position of the porphyrin. Crystal structure analysis revealed that the two phenyl groups at the meso positions of porphyrin extend outside HasA. It was shown that the growth of P. aeruginosa was inhibited in the presence of HasA coordinating the synthetic porphyrins under iron-limiting conditions, and that the structure of the synthetic porphyrins greatly affects the inhibition efficiency.

-	~~Authors: Shoji~~, O., Uehara, H., ~~Sugimoto~~, H., Shiro, Y., ~~Watanabe~~, Y.	+	Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group.,Uehara H, Shisaka Y, Nishimura T, Sugimoto H, Shiro Y, Miyake Y, Shinokubo H, Watanabe Y, Shoji O Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15279-15283. doi:, 10.1002/anie.201707212. Epub 2017 Oct 9. PMID:28921809<ref>PMID:28921809</ref>

-	~~Description: Crystal Structure~~ of ~~HasAp with Fe~~-~~5,15~~-~~bisethynyl-10,20-diphenylporphyrin~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5xkb" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Shiro, Y]]		[[Category: Shiro, Y]]
-	[[Category: Sugimoto, H]]
	[[Category: Shoji, O]]		[[Category: Shoji, O]]
		+	[[Category: Sugimoto, H]]
	[[Category: Uehara, H]]		[[Category: Uehara, H]]
	[[Category: Watanabe, Y]]		[[Category: Watanabe, Y]]
		+	[[Category: Heme acquisition protein]]
		+	[[Category: Transport protein]]

OCA at 15:32, 27 September 2017

2017-09-27T15:32:10Z

←Older revision		Revision as of 15:32, 27 September 2017
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Shiro, Y]]		[[Category: Shiro, Y]]
-	[[Category: Uehara, H]]
	[[Category: Sugimoto, H]]		[[Category: Sugimoto, H]]
	[[Category: Shoji, O]]		[[Category: Shoji, O]]
		+	[[Category: Uehara, H]]
	[[Category: Watanabe, Y]]		[[Category: Watanabe, Y]]

OCA: Protected "5xkb" [edit=sysop:move=sysop]

2017-05-17T14:53:38Z

Protected "5xkb" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:53, 17 May 2017

OCA: New page: '''Unreleased structure''' The entry 5xkb is ON HOLD Authors: Shoji, O., Uehara, H., Sugimoto, H., Shiro, Y., Watanabe, Y. Description: Crystal Structure of HasAp with Fe-5,15-bisethyn...

2017-05-17T14:53:37Z

New page: '''Unreleased structure''' The entry 5xkb is ON HOLD Authors: Shoji, O., Uehara, H., Sugimoto, H., Shiro, Y., Watanabe, Y. Description: Crystal Structure of HasAp with Fe-5,15-bisethyn...

New page

'''Unreleased structure'''

The entry 5xkb is ON HOLD

Authors: Shoji, O., Uehara, H., Sugimoto, H., Shiro, Y., Watanabe, Y.

Description: Crystal Structure of HasAp with Fe-5,15-bisethynyl-10,20-diphenylporphyrin
[[Category: Unreleased Structures]]
[[Category: Shiro, Y]]
[[Category: Uehara, H]]
[[Category: Sugimoto, H]]
[[Category: Shoji, O]]
[[Category: Watanabe, Y]]