5xnd - Revision history

OCA at 10:31, 14 June 2023

2023-06-14T10:31:19Z

←Older revision		Revision as of 10:31, 14 June 2023
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	==Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel==		==Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel==
-	<StructureSection load='5xnd' size='340' side='right'caption='[[5xnd~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='5xnd' size='340' side='right'caption='[[5xnd]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xnd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XND OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XND FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xnd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Scomber_japonicus Scomber japonicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XND FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnd OCA], [~~http~~://pdbe.org/5xnd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xnd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xnd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnd OCA], [https://pdbe.org/5xnd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xnd RCSB], [https://www.ebi.ac.uk/pdbsum/5xnd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PRVB_SCOJP PRVB_SCOJP]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	+	[https://www.uniprot.org/uniprot/PRVB_SCOJP PRVB_SCOJP] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Kumeta, H~~]]	+	[[Category: Scomber japonicus]]
-	[[Category: ~~Nakayama,~~ H]]	+	[[Category: Kumeta H]]
-	[[Category: ~~Ogura, K~~]]	+	[[Category: Nakayama H]]
-	[[Category: ~~Metal binding protein]]~~	+	[[Category: Ogura K]]
-	~~[[Category: Structure from cyana 2 1~~]]	+

OCA at 06:55, 14 October 2020

2020-10-14T06:55:19Z

←Older revision		Revision as of 06:55, 14 October 2020
Line 1:		Line 1:

	==Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel==		==Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel==
-	<StructureSection load='5xnd' size='340' side='right' caption='[[5xnd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='5xnd' size='340' side='right'caption='[[5xnd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xnd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XND OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XND FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xnd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XND OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XND FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnd OCA], [http://pdbe.org/5xnd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xnd RCSB], [http://www.ebi.ac.uk/pdbsum/5xnd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnd OCA], [http://pdbe.org/5xnd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xnd RCSB], [http://www.ebi.ac.uk/pdbsum/5xnd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 5xnd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5xnd" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Parvalbumin\|Parvalbumin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Kumeta, H]]		[[Category: Kumeta, H]]
	[[Category: Nakayama, H]]		[[Category: Nakayama, H]]

OCA at 08:30, 27 December 2017

2017-12-27T08:30:35Z

←Older revision		Revision as of 08:30, 27 December 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5xnd is ~~ON HOLD until Paper~~ Publication	+	==Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel==
		+	<StructureSection load='5xnd' size='340' side='right' caption='[[5xnd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xnd]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XND OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XND FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnd OCA], [http://pdbe.org/5xnd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xnd RCSB], [http://www.ebi.ac.uk/pdbsum/5xnd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnd ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRVB_SCOJP PRVB_SCOJP]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Although fish is an important part of the human diet, it is also a common source of food allergy. The major allergen in fish is parvalbumin, a well-conserved Ca(2+)-binding protein found in the white muscle of many fish species. Here, we studied the solution structure of the parvalbumin Sco j 1, derived from the Pacific mackerel, using nuclear magnetic resonance spectroscopy. We mapped the IgE-binding epitope proposed in a recent study onto the present structure. Interestingly, three of four residues, which were elucidated as key residues of the IgE-binding epitope, were exposed to solvent, whereas one residue faced the inside of the molecule. We expect that this solution structure can be used in future studies attempting to analyze the various IgE-binding modes of these allergens.

-	~~Authors: Kumeta~~, H., Nakayama, H., Ogura, K.	+	Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel.,Kumeta H, Nakayama H, Ogura K Sci Rep. 2017 Dec 7;7(1):17160. doi: 10.1038/s41598-017-17281-6. PMID:29215073<ref>PMID:29215073</ref>

-	~~Description: Solution structure~~ of the ~~major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5xnd" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Kumeta, H]]		[[Category: Kumeta, H]]
-	[[Category: Ogura, K]]
	[[Category: Nakayama, H]]		[[Category: Nakayama, H]]
		+	[[Category: Ogura, K]]
		+	[[Category: Metal binding protein]]
		+	[[Category: Structure from cyana 2 1]]

OCA: Protected "5xnd" [edit=sysop:move=sysop]

2017-09-27T15:35:38Z

Protected "5xnd" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:35, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5xnd is ON HOLD until Paper Publication Authors: Kumeta, H., Nakayama, H., Ogura, K. Description: Solution structure of the major fish allergen par...

2017-09-27T15:35:37Z

New page: '''Unreleased structure''' The entry 5xnd is ON HOLD until Paper Publication Authors: Kumeta, H., Nakayama, H., Ogura, K. Description: Solution structure of the major fish allergen par...

New page

'''Unreleased structure'''

The entry 5xnd is ON HOLD until Paper Publication

Authors: Kumeta, H., Nakayama, H., Ogura, K.

Description: Solution structure of the major fish allergen parvalbumin Sco j 1 derived from the Pacific mackerel
[[Category: Unreleased Structures]]
[[Category: Kumeta, H]]
[[Category: Ogura, K]]
[[Category: Nakayama, H]]