5xta - Revision history

OCA at 06:58, 14 October 2020

2020-10-14T06:58:33Z

OCA: Protected "5xta" [edit=sysop:move=sysop]

2017-08-17T06:02:28Z

Protected "5xta" [edit=sysop:move=sysop]

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Revision as of 06:02, 17 August 2017

OCA: New page: ==Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila== == Structural highlights ==
<table><tr><td colspan='2'>[[5xta]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XTA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xta OCA], [http://pdbe.org/5xta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xta RCSB], [http://www.ebi.ac.uk/pdbsum/5xta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xta ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
VirK family [Pfam06903] consists of 14 bacterial VirK proteins of around 145 residues in length. The function of this family is unknown. Herein, using single-wavelength anomalous diffraction (SAD), we determined the crystal structure of lpg1832, a VirK family protein from Legionella pneumophila, at 2.0 A resolution. This is the first structural determination of a VirK domain-containing protein. Lpg1832 is a type II secretion system-dependent extracellular protein that folds into a novel barrel-shaped structure. It is found to adopt a quaternary assembly comprising a homotetramer. The three-dimensional structure of lpg1832 provides the first structural information pertaining to the VirK family and allows us to possibly identify its functionally important regions. This article is protected by copyright. All rights reserved.

Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila, reveals a novel fold for bacterial VirK proteins.,Zhang N, Yin S, Liu S, Sun A, Zhou M, Gong X, Ge H FEBS Lett. 2017 Aug 3. doi: 10.1002/1873-3468.12773. PMID:28771688<ref>PMID:28771688</ref>

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5xta" style="background-color:#fffaf0;"></div>
== References ==
<references/>
TOC
</StructureSection>
[[Category: Ge, H]]
[[Category: Gong, X]]
[[Category: Yin, S]]
[[Category: Zhang, N]]
[[Category: Novel fold]]
[[Category: Oxidoreductase]]
[[Category: Type ii secretion]]