5xvx - Revision history

OCA at 10:20, 27 March 2024

2024-03-27T10:20:43Z

←Older revision		Revision as of 10:20, 27 March 2024
Line 3:		Line 3:
	<StructureSection load='5xvx' size='340' side='right'caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='5xvx' size='340' side='right'caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XVX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [~~http~~://pdbe.org/5xvx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [https://pdbe.org/5xvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [https://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/B6V7E4_ASPNG B6V7E4_ASPNG]
-	Glutamate dehydrogenase (GDH) is a key enzyme connecting carbon and nitrogen metabolism in all living organisms. Despite extensive studies on GDHs from both prokaryotic and eukaryotic organisms in the last 40 years, the structural basis of the catalytic features of this enzyme remains incomplete. This study reports the structural basis of the GDH catalytic mechanism and allosteric behavior. We determined the first high-resolution crystal structures of glutamate dehydrogenase from the fungus Aspergillus niger (AnGDH), a unique NADP(+)-dependent allosteric enzyme that is forward inhibited by the formation of mixed disulfide. We determined the structures of the active enzyme in its apo form and in binary/ternary complexes with bound substrate (alpha- ketoglutarate), inhibitor (isophthalate), coenzyme (NADPH), or two reaction intermediates (alpha-iminoglutarate and 2-amino-2-hydroxyglutarate). The structure of the forward-inhibited enzyme (fiAnGDH) was also determined. The hexameric AnGDH had three open subunits at one side and three partially closed protomers at the other, a configuration not previously been reported. The AnGDH hexamers having subunits with different conformations indicated that its alpha-ketoglutarate-dependent homotropic cooperativity follows the Monod-Wyman-Changeux (MWC) model. Moreover, the position of the water attached to Asp154 and Gly153 defined the previously unresolved ammonium ion-binding pocket, and the binding site for the 2'-phosphate group of the coenzyme was also better defined by our structural data. Additional structural and mutagenesis experiments identified the residues essential for coenzyme recognition. This study reveals the structural features responsible for positioning alpha-ketoglutarate, NADPH, ammonium ion, and the reaction intermediates in the GDH active site.	+
-		+
-	~~Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.,Prakash P, Punekar NS, Bhaumik P J Biol Chem. 2018 Mar 14. pii~~: ~~RA117.000149. doi: 10.1074~~/~~jbc.RA117.000149. PMID:29540480<ref>PMID:29540480<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 5xvx" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Glutamate dehydrogenase 3D structures\|Glutamate dehydrogenase 3D structures]]		*[[Glutamate dehydrogenase 3D structures\|Glutamate dehydrogenase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Aspergillus niger]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bhaumik, P]]	+	[[Category: Bhaumik P]]
-	[[Category: Prakash, P]]	+	[[Category: Prakash P]]
-	[[Category: Punekar~~, N S]]~~	+	[[Category: Punekar NS]]
-	~~[[Category: 2-oxoglutarate]]~~	+
-	~~[[Category: Allostery]]~~	+
-	~~[[Category: Aspergillus]]~~	+
-	~~[[Category: Coenzyme]]~~	+
-	~~[[Category: Dehydrogenase]]~~	+
-	~~[[Category: Glutamate]]~~	+
-	~~[[Category: Nadph]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Reaction mechanism~~]]	+

OCA at 06:59, 14 October 2020

2020-10-14T06:59:41Z

←Older revision		Revision as of 06:59, 14 October 2020
Line 1:		Line 1:

	==Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH==		==Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH==
-	<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='5xvx' size='340' side='right'caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XVX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 5xvx" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5xvx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutamate dehydrogenase 3D structures\|Glutamate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bhaumik, P]]		[[Category: Bhaumik, P]]
	[[Category: Prakash, P]]		[[Category: Prakash, P]]

OCA at 06:28, 9 May 2018

2018-05-09T06:28:46Z

←Older revision		Revision as of 06:28, 9 May 2018
Line 3:		Line 3:
	<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/A._niger A. niger]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: A. niger]]
	[[Category: Bhaumik, P]]		[[Category: Bhaumik, P]]
	[[Category: Prakash, P]]		[[Category: Prakash, P]]

OCA at 07:08, 28 March 2018

2018-03-28T07:08:11Z

←Older revision		Revision as of 07:08, 28 March 2018
Line 3:		Line 3:
	<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/A._niger A. niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutamate dehydrogenase (GDH) is a key enzyme connecting carbon and nitrogen metabolism in all living organisms. Despite extensive studies on GDHs from both prokaryotic and eukaryotic organisms in the last 40 years, the structural basis of the catalytic features of this enzyme remains incomplete. This study reports the structural basis of the GDH catalytic mechanism and allosteric behavior. We determined the first high-resolution crystal structures of glutamate dehydrogenase from the fungus Aspergillus niger (AnGDH), a unique NADP(+)-dependent allosteric enzyme that is forward inhibited by the formation of mixed disulfide. We determined the structures of the active enzyme in its apo form and in binary/ternary complexes with bound substrate (alpha- ketoglutarate), inhibitor (isophthalate), coenzyme (NADPH), or two reaction intermediates (alpha-iminoglutarate and 2-amino-2-hydroxyglutarate). The structure of the forward-inhibited enzyme (fiAnGDH) was also determined. The hexameric AnGDH had three open subunits at one side and three partially closed protomers at the other, a configuration not previously been reported. The AnGDH hexamers having subunits with different conformations indicated that its alpha-ketoglutarate-dependent homotropic cooperativity follows the Monod-Wyman-Changeux (MWC) model. Moreover, the position of the water attached to Asp154 and Gly153 defined the previously unresolved ammonium ion-binding pocket, and the binding site for the 2'-phosphate group of the coenzyme was also better defined by our structural data. Additional structural and mutagenesis experiments identified the residues essential for coenzyme recognition. This study reveals the structural features responsible for positioning alpha-ketoglutarate, NADPH, ammonium ion, and the reaction intermediates in the GDH active site.
		+
		+	Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.,Prakash P, Punekar NS, Bhaumik P J Biol Chem. 2018 Mar 14. pii: RA117.000149. doi: 10.1074/jbc.RA117.000149. PMID:29540480<ref>PMID:29540480</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5xvx" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: A. niger]]
	[[Category: Bhaumik, P]]		[[Category: Bhaumik, P]]
	[[Category: Prakash, P]]		[[Category: Prakash, P]]

OCA at 07:34, 21 March 2018

2018-03-21T07:34:37Z

←Older revision		Revision as of 07:34, 21 March 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5xvx is ~~ON HOLD until Paper Publication~~	+	==Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH==
-		+	<StructureSection load='5xvx' size='340' side='right' caption='[[5xvx]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~Authors~~: ~~Prakash~~, P., ~~Punekar~~, N.S., ~~Bhaumik~~, P.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5xvx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVX FirstGlance]. <br>
-	~~Description: Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvx OCA], [http://pdbe.org/5xvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvx RCSB], [http://www.ebi.ac.uk/pdbsum/5xvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvx ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bhaumik, P]]
	[[Category: Prakash, P]]		[[Category: Prakash, P]]
-	[[Category: Punekar, N.S]]	+	[[Category: Punekar, N S]]
-	[[Category: ~~Bhaumik, P~~]]	+	[[Category: 2-oxoglutarate]]
		+	[[Category: Allostery]]
		+	[[Category: Aspergillus]]
		+	[[Category: Coenzyme]]
		+	[[Category: Dehydrogenase]]
		+	[[Category: Glutamate]]
		+	[[Category: Nadph]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Reaction mechanism]]

OCA at 04:55, 7 February 2018

2018-02-07T04:55:47Z

←Older revision		Revision as of 04:55, 7 February 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xvx is ON HOLD	+	The entry 5xvx is ON HOLD until Paper Publication

	Authors: Prakash, P., Punekar, N.S., Bhaumik, P.		Authors: Prakash, P., Punekar, N.S., Bhaumik, P.
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Prakash, P]]		[[Category: Prakash, P]]
-	[[Category: Bhaumik, P]]
	[[Category: Punekar, N.S]]		[[Category: Punekar, N.S]]
		+	[[Category: Bhaumik, P]]

OCA at 05:29, 17 January 2018

2018-01-17T05:29:33Z

←Older revision		Revision as of 05:29, 17 January 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xvx is ON HOLD ~~until Paper Publication~~	+	The entry 5xvx is ON HOLD

	Authors: Prakash, P., Punekar, N.S., Bhaumik, P.		Authors: Prakash, P., Punekar, N.S., Bhaumik, P.

OCA: Protected "5xvx" [edit=sysop:move=sysop]

2017-09-27T15:50:18Z

Protected "5xvx" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:50, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5xvx is ON HOLD until Paper Publication Authors: Prakash, P., Punekar, N.S., Bhaumik, P. Description: Crystal Structure of Aspergillus niger Glutam...

2017-09-27T15:50:17Z

New page: '''Unreleased structure''' The entry 5xvx is ON HOLD until Paper Publication Authors: Prakash, P., Punekar, N.S., Bhaumik, P. Description: Crystal Structure of Aspergillus niger Glutam...

New page

'''Unreleased structure'''

The entry 5xvx is ON HOLD until Paper Publication

Authors: Prakash, P., Punekar, N.S., Bhaumik, P.

Description: Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH
[[Category: Unreleased Structures]]
[[Category: Prakash, P]]
[[Category: Bhaumik, P]]
[[Category: Punekar, N.S]]