5za0 - Revision history

OCA at 08:50, 22 November 2023

2023-11-22T08:50:29Z

←Older revision		Revision as of 08:50, 22 November 2023
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	<StructureSection load='5za0' size='340' side='right'caption='[[5za0]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='5za0' size='340' side='right'caption='[[5za0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5za0]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Escherichia_coli_k~~-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZA0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5ZA0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5za0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZA0 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GLC:ALPHA~~-~~D-GLUCOSE'>GLC</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[http~~:~~//en.wikipedia.org/wiki/Glyceraldehyde~~-3-~~phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]~~, ~~with EC number [http~~:/~~/www.brenda-enzymes.info/php/result_flat.php4?ecno~~=~~1.2.1.12 1.2.1.12]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900006:trehalose'>PRD_900006</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5za0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5za0 OCA], [~~http~~://pdbe.org/5za0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5za0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5za0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5za0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5za0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5za0 OCA], [https://pdbe.org/5za0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5za0 RCSB], [https://www.ebi.ac.uk/pdbsum/5za0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5za0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G3P1_ECOLI G3P1_ECOLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Escherichia coli k-12]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kim~~, Y J]]~~	+	[[Category: Kim YJ]]
-	~~[[Category: Cryo-protectant]]~~	+
-	~~[[Category: Glycolysis]]~~	+
-	~~[[Category: Hypothetical]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 21:17, 28 October 2020

2020-10-28T21:17:05Z

←Older revision		Revision as of 21:17, 28 October 2020
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	==A cryo-protectant induces the conformational change of glyceraldehyde-3-phosphate dehydrogenase==		==A cryo-protectant induces the conformational change of glyceraldehyde-3-phosphate dehydrogenase==
-	<StructureSection load='5za0' size='340' side='right' caption='[[5za0]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='5za0' size='340' side='right'caption='[[5za0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5za0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZA0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZA0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5za0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZA0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ZA0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~SO4~~:~~SULFATE+ION~~'>~~SO4~~</scene>, <scene name='pdbligand=~~TRE~~:~~TREHALOSE~~'>~~TRE~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5za0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5za0 OCA], [http://pdbe.org/5za0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5za0 RCSB], [http://www.ebi.ac.uk/pdbsum/5za0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5za0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5za0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5za0 OCA], [http://pdbe.org/5za0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5za0 RCSB], [http://www.ebi.ac.uk/pdbsum/5za0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5za0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Glyceraldehyde-3-~~Phosphate Dehydrogenase~~\|Glyceraldehyde-3-~~Phosphate Dehydrogenase~~]]	+	*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures\|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
		+	[[Category: Large Structures]]
	[[Category: Kim, Y J]]		[[Category: Kim, Y J]]
	[[Category: Cryo-protectant]]		[[Category: Cryo-protectant]]

OCA at 06:27, 18 October 2018

2018-10-18T06:27:50Z

←Older revision		Revision as of 06:27, 18 October 2018
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	</div>		</div>
	<div class="pdbe-citations 5za0" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5za0" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glyceraldehyde-3-Phosphate Dehydrogenase\|Glyceraldehyde-3-Phosphate Dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:30, 30 May 2018

2018-05-30T05:30:07Z

←Older revision		Revision as of 05:30, 30 May 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 5za0 is ~~ON HOLD~~	+	==A cryo-protectant induces the conformational change of glyceraldehyde-3-phosphate dehydrogenase==
		+	<StructureSection load='5za0' size='340' side='right' caption='[[5za0]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5za0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZA0 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRE:TREHALOSE'>TRE</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5za0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5za0 OCA], [http://pdbe.org/5za0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5za0 RCSB], [http://www.ebi.ac.uk/pdbsum/5za0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5za0 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a glycolytic enzyme, catalyses the conversion of D-glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate. While mammalian and yeast GAPDHs are multifunctional proteins that have additional functions beyond those involved in glycolysis, including reactions related to nuclear RNA transport, DNA replication/repair, membrane fusion and cellular apoptosis, Escherichia coli GAPDH (ecGAPDH) has only been reported to function in glycolysis. The S-loop of GAPDH is required for interaction with its cofactor and with other proteins. In this study, the three-dimensional crystal structure of GAPDH treated with trehalose is reported at 2.0 A resolution. Trehalose was used as a cryoprotectant for the GAPDH crystals. The structure of trehalose-bound ecGAPDH was compared with the structures of both NAD(+)-free and NAD(+)-bound ecGAPDH. At the S-loop, the bound trehalose in the GAPDH structure induces a 2.4 degrees rotation compared with the NAD(+)-free ecGAPDH structure and a 3.1 degrees rotation compared with the NAD(+)-bound ecGAPDH structure.

-	~~Authors~~:	+	A cryoprotectant induces conformational change in glyceraldehyde-3-phosphate dehydrogenase.,Kim YJ Acta Crystallogr F Struct Biol Commun. 2018 May 1;74(Pt 5):277-282. doi:, 10.1107/S2053230X18004557. Epub 2018 Apr 16. PMID:29717994<ref>PMID:29717994</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5za0" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Escherichia coli k-12]]
		+	[[Category: Kim, Y J]]
		+	[[Category: Cryo-protectant]]
		+	[[Category: Glycolysis]]
		+	[[Category: Hypothetical]]
		+	[[Category: Oxidoreductase]]

OCA at 03:48, 25 April 2018

2018-04-25T03:48:42Z

←Older revision		Revision as of 03:48, 25 April 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5za0 is ON HOLD ~~until Paper Publication~~	+	The entry 5za0 is ON HOLD

	Authors:		Authors:

OCA at 05:55, 21 March 2018

2018-03-21T05:55:56Z

←Older revision		Revision as of 05:55, 21 March 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5za0 is ON HOLD	+	The entry 5za0 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5za0" [edit=sysop:move=sysop]

2018-02-15T05:10:53Z

Protected "5za0" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:10, 15 February 2018

OCA: New page: '''Unreleased structure''' The entry 5za0 is ON HOLD Authors: Description: Category: Unreleased Structures

2018-02-15T05:10:52Z

New page: '''Unreleased structure''' The entry 5za0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5za0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]