6a0n - Revision history

OCA at 21:25, 28 October 2020

2020-10-28T21:25:18Z

←Older revision		Revision as of 21:25, 28 October 2020
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	==The crystal structure of apo-Lpg2622==		==The crystal structure of apo-Lpg2622==
-	<StructureSection load='6a0n' size='340' side='right' caption='[[6a0n]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='6a0n' size='340' side='right'caption='[[6a0n]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6a0n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A0N OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6A0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6a0n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A0N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6A0N FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6a0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a0n OCA], [http://pdbe.org/6a0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a0n RCSB], [http://www.ebi.ac.uk/pdbsum/6a0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a0n ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6a0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a0n OCA], [http://pdbe.org/6a0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a0n RCSB], [http://www.ebi.ac.uk/pdbsum/6a0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a0n ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ge, H]]		[[Category: Ge, H]]
	[[Category: Gong, X]]		[[Category: Gong, X]]
	[[Category: Cysteine protease]]		[[Category: Cysteine protease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:29, 12 September 2018

2018-09-12T07:29:48Z

←Older revision		Revision as of 07:29, 12 September 2018
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-	'''Unreleased structure'''

-	The ~~entry~~ 6a0n is ~~ON HOLD until Paper~~ Publication	+	==The crystal structure of apo-Lpg2622==
		+	<StructureSection load='6a0n' size='340' side='right' caption='[[6a0n]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6a0n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A0N FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a0n OCA], [http://pdbe.org/6a0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a0n RCSB], [http://www.ebi.ac.uk/pdbsum/6a0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a0n ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Legionella pneumophila type II secretion system can promote bacterial growth under a wide variety of conditions and mediates the secretion of more than 25 proteins, including the uncharacterized effector Lpg2622. Here, we determined the crystal structures of apo-Lpg2622 and Lpg2622 in complex with the cysteine protease inhibitor E64. Structural analysis suggests that Lpg2622 belongs to the C1 family peptidases. Interestingly, unlike the other structurally resolved papain-like cysteine proteases, the propeptide of Lpg2622 forms a novel super-secondary structural fold (hairpin-turn-helix) and can be categorized into a new group. In addition, the N-terminal beta-sheet of the Lpg2622 propeptide plays a regulatory role on enzymatic activity. This study enhances our understanding of the classification and regulatory mechanisms of the C1 family peptidases.

-	~~Authors:~~ Gong, X., Ge, H.	+	Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila.,Gong X, Zhao X, Zhang W, Wang J, Chen X, Hameed MF, Zhang N, Ge H FEBS Lett. 2018 Aug;592(16):2798-2810. doi: 10.1002/1873-3468.13210. Epub 2018, Aug 20. PMID:30071124<ref>PMID:30071124</ref>

-	~~Description: The crystal structure~~ of ~~apo-Lpg2622~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 6a0n" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Ge, H]]		[[Category: Ge, H]]
	[[Category: Gong, X]]		[[Category: Gong, X]]
		+	[[Category: Cysteine protease]]
		+	[[Category: Hydrolase]]

OCA at 03:53, 20 June 2018

2018-06-20T03:53:05Z

←Older revision		Revision as of 03:53, 20 June 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6a0n is ON HOLD	+	The entry 6a0n is ON HOLD until Paper Publication

-	Authors: ~~Xiaojian~~, G., ~~Honghua~~, G.	+	Authors: Gong, X., Ge, H.

	Description: The crystal structure of apo-Lpg2622		Description: The crystal structure of apo-Lpg2622
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Honghua~~, G]]	+	[[Category: Ge, H]]
-	[[Category: ~~Xiaojian~~, G]]	+	[[Category: Gong, X]]

OCA: Protected "6a0n" [edit=sysop:move=sysop]

2018-06-14T05:27:51Z

Protected "6a0n" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:27, 14 June 2018

OCA: New page: '''Unreleased structure''' The entry 6a0n is ON HOLD Authors: Xiaojian, G., Honghua, G. Description: The crystal structure of apo-Lpg2622 Category: Unreleased Structures [[Category...

2018-06-14T05:27:49Z

New page: '''Unreleased structure''' The entry 6a0n is ON HOLD Authors: Xiaojian, G., Honghua, G. Description: The crystal structure of apo-Lpg2622 Category: Unreleased Structures [[Category...

New page

'''Unreleased structure'''

The entry 6a0n is ON HOLD

Authors: Xiaojian, G., Honghua, G.

Description: The crystal structure of apo-Lpg2622
[[Category: Unreleased Structures]]
[[Category: Honghua, G]]
[[Category: Xiaojian, G]]