6b6j - Revision history

OCA at 14:33, 4 October 2023

2023-10-04T14:33:45Z

←Older revision		Revision as of 14:33, 4 October 2023
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	<StructureSection load='6b6j' size='340' side='right'caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6b6j' size='340' side='right'caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Artvu Artvu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6B6J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Artemisia_vulgaris Artemisia vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B6J FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">[[~~5em0~~\|~~5em0~~]]</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [~~http~~://pdbe.org/6b6j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [https://pdbe.org/6b6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [https://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PROF1_ARTVU PROF1_ARTVU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Artvu~~]]	+	[[Category: Artemisia vulgaris]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chruszcz, M]]	+	[[Category: Chruszcz M]]
-	[[Category: Pote~~, S S~~]]	+	[[Category: Pote SS]]
-	[[Category: Pye~~, S E]]~~	+	[[Category: Pye SE]]
-	~~[[Category: Allergen]]~~	+
-	~~[[Category: Mugwort]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Pollen~~]]	+

OCA at 17:43, 11 December 2019

2019-12-11T17:43:58Z

←Older revision		Revision as of 17:43, 11 December 2019
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	</div>		</div>
	<div class="pdbe-citations 6b6j" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6b6j" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Profilin 3D Structures\|Profilin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:13, 7 August 2019

2019-08-07T06:13:24Z

←Older revision		Revision as of 06:13, 7 August 2019
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	==Structure of profilin Art v4==		==Structure of profilin Art v4==
-	<StructureSection load='6b6j' size='340' side='right' caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='6b6j' size='340' side='right'caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Artvu Artvu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6J FirstGlance]. <br>		<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Artvu Artvu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6J FirstGlance]. <br>
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [http://pdbe.org/6b6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [http://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [http://pdbe.org/6b6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [http://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Worldwide, more than one-third of the population suffers from allergies. A significant fraction of officially registered allergens originate from the profilin family of proteins. Profilins are small ubiquitous proteins which are found in plants, viruses and various eukaryotes including mammals. Although they are primarily regarded as minor allergens, profilins are important players in immunoglobulin E (IgE) cross-reactivity. However, in some populations profilins are recognized by IgE from at least 50% of patients allergic to a given allergen source. Cuc m 2.0101 is recognized by IgE in more than 80% of muskmelon-allergic patients. The recombinant isoallergen Cuc m 2.0101 was produced in significant quantities and its X-ray crystal structure was determined. In addition, a new Art v 4.0101 (mugwort profilin) structure was determined. The profilins Cuc m 2.0101 and Art v 4.0101 were compared in terms of their structure and thermal stability. Furthermore, structural similarities and IgE cross-reactivity between profilins from different sources are discussed to explain the molecular basis of various clinical syndromes involving this group of allergens. Special emphasis is placed on discussion of profilins' quaternary structures and their relation to biological function, as well as to protein allergenicity. Moreover, a potential impact of protein purification protocols on the structure of profilins is highlighted.
		+
		+	Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins.,Kapingidza AB, Pye SE, Hyduke N, Dolamore C, Pote S, Schlachter CR, Commins SP, Kowal K, Chruszcz M Mol Immunol. 2019 Jul 18;114:19-29. doi: 10.1016/j.molimm.2019.07.004. PMID:31326654<ref>PMID:31326654</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6b6j" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Artvu]]		[[Category: Artvu]]
		+	[[Category: Large Structures]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]
	[[Category: Pote, S S]]		[[Category: Pote, S S]]

OCA at 07:46, 21 February 2019

2019-02-21T07:46:36Z

←Older revision		Revision as of 07:46, 21 February 2019
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	<StructureSection load='6b6j' size='340' side='right' caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6b6j' size='340' side='right' caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Artvu Artvu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6J FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5em0\|5em0]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5em0\|5em0]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [http://pdbe.org/6b6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [http://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [http://pdbe.org/6b6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [http://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Artvu]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]
	[[Category: Pote, S S]]		[[Category: Pote, S S]]

OCA at 07:44, 3 October 2018

2018-10-03T07:44:43Z

←Older revision		Revision as of 07:44, 3 October 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6b6j ~~is ON HOLD until Oct 02 2019~~	+	==Structure of profilin Art v4==
-		+	<StructureSection load='6b6j' size='340' side='right' caption='[[6b6j]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Pye, S~~.E.~~, Pote, S~~.S.~~, Chruszcz, M~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6b6j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6J FirstGlance]. <br>
-	~~Description: Structure of profilin Art v4~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5em0\|5em0]]</td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6j OCA], [http://pdbe.org/6b6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6j RCSB], [http://www.ebi.ac.uk/pdbsum/6b6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6j ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Pye~~, S.E]]	+	</table>
-	[[~~Category~~: ~~Pote~~, S.S]]	+	__TOC__
		+	</StructureSection>
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]
		+	[[Category: Pote, S S]]
		+	[[Category: Pye, S E]]
		+	[[Category: Allergen]]
		+	[[Category: Mugwort]]
		+	[[Category: Plant protein]]
		+	[[Category: Pollen]]

OCA at 04:43, 31 January 2018

2018-01-31T04:43:28Z

←Older revision		Revision as of 04:43, 31 January 2018
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	The entry 6b6j is ON HOLD until Oct 02 2019		The entry 6b6j is ON HOLD until Oct 02 2019

-	Authors: Pye, S.E., Pote, S.P., Chruszcz, M.	+	Authors: Pye, S.E., Pote, S.S., Chruszcz, M.

	Description: Structure of profilin Art v4		Description: Structure of profilin Art v4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Pye, S.E]]		[[Category: Pye, S.E]]
-	[[Category: Pote, S.P]]	+	[[Category: Pote, S.S]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]

OCA at 05:46, 25 October 2017

2017-10-25T05:46:05Z

←Older revision		Revision as of 05:46, 25 October 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6b6j is ON HOLD	+	The entry 6b6j is ON HOLD until Oct 02 2019

	Authors: Pye, S.E., Pote, S.P., Chruszcz, M.		Authors: Pye, S.E., Pote, S.P., Chruszcz, M.
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	Description: Structure of profilin Art v4		Description: Structure of profilin Art v4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Chruszcz, M]]
	[[Category: Pye, S.E]]		[[Category: Pye, S.E]]
	[[Category: Pote, S.P]]		[[Category: Pote, S.P]]
		+	[[Category: Chruszcz, M]]

OCA: Protected "6b6j" [edit=sysop:move=sysop]

2017-10-11T05:32:29Z

Protected "6b6j" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:32, 11 October 2017

OCA: New page: '''Unreleased structure''' The entry 6b6j is ON HOLD Authors: Pye, S.E., Pote, S.P., Chruszcz, M. Description: Structure of profilin Art v4 Category: Unreleased Structures [[Catego...

2017-10-11T05:32:27Z

New page: '''Unreleased structure''' The entry 6b6j is ON HOLD Authors: Pye, S.E., Pote, S.P., Chruszcz, M. Description: Structure of profilin Art v4 Category: Unreleased Structures [[Catego...

New page

'''Unreleased structure'''

The entry 6b6j is ON HOLD

Authors: Pye, S.E., Pote, S.P., Chruszcz, M.

Description: Structure of profilin Art v4
[[Category: Unreleased Structures]]
[[Category: Chruszcz, M]]
[[Category: Pye, S.E]]
[[Category: Pote, S.P]]