6bia - Revision history

OCA at 14:41, 4 October 2023

2023-10-04T14:41:46Z

←Older revision		Revision as of 14:41, 4 October 2023
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	<StructureSection load='6bia' size='340' side='right'caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='6bia' size='340' side='right'caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Alteromonas_fuliginea Alteromonas~~ fuliginea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6BIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudoalteromonas_fuliginea Pseudoalteromonas fuliginea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BIA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=CA:CALCIUM+ION'>CA</scene~~>, ~~<scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,~~2~~-ETHANEDIOL'>EDO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[6b0k\|6b0k]], [[6b0j\|6b0j]], [[6b1v\|6b1v]]~~<~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<~~tr id~~='~~gene~~'><~~td class="sblockLbl"~~><~~b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">DC53_12720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1872678 Alteromonas fuliginea])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [https://pdbe.org/6bia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [https://www.ebi.ac.uk/pdbsum/6bia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [~~http~~://pdbe.org/6bia PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6bia PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Sulfatase\|Sulfatase]]	+	*[[Sulfatase 3D structures\|Sulfatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Alteromonas fuliginea]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Boraston, A B~~]]	+	[[Category: Pseudoalteromonas fuliginea]]
-	[[Category: ~~Hettle, A G~~]]	+	[[Category: Boraston AB]]
-	[[Category: ~~Oxidoreductase]]~~	+	[[Category: Hettle AG]]
-	~~[[Category: S1 sulfatase~~]]	+

OCA at 08:35, 8 January 2020

2020-01-08T08:35:18Z

←Older revision		Revision as of 08:35, 8 January 2020
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	==Crystal structure of Ps i-CgsB==		==Crystal structure of Ps i-CgsB==
-	<StructureSection load='6bia' size='340' side='right' caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='6bia' size='340' side='right'caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Alteromonas_fuliginea Alteromonas fuliginea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIA FirstGlance]. <br>		<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Alteromonas_fuliginea Alteromonas fuliginea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIA FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Alteromonas fuliginea]]		[[Category: Alteromonas fuliginea]]
		+	[[Category: Large Structures]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
	[[Category: Hettle, A G]]		[[Category: Hettle, A G]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: S1 sulfatase]]		[[Category: S1 sulfatase]]

OCA at 07:51, 21 February 2019

2019-02-21T07:51:15Z

←Older revision		Revision as of 07:51, 21 February 2019
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	</div>		</div>
	<div class="pdbe-citations 6bia" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6bia" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Sulfatase\|Sulfatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:57, 16 May 2018

2018-05-16T05:57:20Z

←Older revision		Revision as of 05:57, 16 May 2018
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	<StructureSection load='6bia' size='340' side='right' caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='6bia' size='340' side='right' caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Alteromonas_fuliginea Alteromonas fuliginea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6b0k\|6b0k]], [[6b0j\|6b0j]], [[6b1v\|6b1v]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6b0k\|6b0k]], [[6b0j\|6b0j]], [[6b1v\|6b1v]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DC53_12720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1872678 Alteromonas fuliginea])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [http://pdbe.org/6bia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [http://www.ebi.ac.uk/pdbsum/6bia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [http://pdbe.org/6bia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [http://www.ebi.ac.uk/pdbsum/6bia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Alteromonas fuliginea]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
	[[Category: Hettle, A G]]		[[Category: Hettle, A G]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: S1 sulfatase]]		[[Category: S1 sulfatase]]

OCA at 06:30, 9 May 2018

2018-05-09T06:30:53Z

←Older revision		Revision as of 06:30, 9 May 2018
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [http://pdbe.org/6bia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [http://www.ebi.ac.uk/pdbsum/6bia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [http://pdbe.org/6bia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [http://www.ebi.ac.uk/pdbsum/6bia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sulfatases play a biologically important role by cleaving sulfate groups from molecules. They can be identified on the basis of signature sequences within their primary structures, and the largest family, S1, has predictable features that contribute specifically to the recognition and catalytic removal of sulfate groups. However, despite advances in the prediction and understanding of S1 sulfatases, a major question regards the molecular determinants that drive substrate recognition beyond the targeted sulfate group. Here, through analysis of an endo-4S-iota-carrageenan sulfatase (PsS1_19A) from Pseudoalteromonas sp. PS47, particularly X-ray crystal structures in complex with intact substrates, we show that specific recognition of the substrate leaving group components, in this case carbohydrate, provides the enzyme with specificity for its substrate. On the basis of these results we propose a catalytic subsite nomenclature that we anticipate will form a general foundation for understanding and describing the molecular basis of substrate recognition by sulfatases.
		+
		+	The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme.,Hettle AG, Vickers C, Robb CS, Liu F, Withers SG, Hehemann JH, Boraston AB Structure. 2018 May 1;26(5):747-758.e4. doi: 10.1016/j.str.2018.03.012. Epub 2018, Apr 19. PMID:29681469<ref>PMID:29681469</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6bia" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:30, 14 March 2018

2018-03-14T06:30:08Z

←Older revision		Revision as of 06:30, 14 March 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6bia ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of Ps i-CgsB==
-		+	<StructureSection load='6bia' size='340' side='right' caption='[[6bia]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~Authors~~: ~~Hettle, A~~.G.~~, Boraston, A~~.B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6bia]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIA FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of Ps i~~-~~CgsB~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6b0k\|6b0k]], [[6b0j\|6b0j]], [[6b1v\|6b1v]]</td></tr>
-	[[Category: Boraston, A.B]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bia OCA], [http://pdbe.org/6bia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bia RCSB], [http://www.ebi.ac.uk/pdbsum/6bia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bia ProSAT]</span></td></tr>
-	[[Category: Hettle, A.G]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Boraston, A B]]
		+	[[Category: Hettle, A G]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: S1 sulfatase]]

OCA at 06:33, 22 November 2017

2017-11-22T06:33:03Z

←Older revision		Revision as of 06:33, 22 November 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6bia is ON HOLD	+	The entry 6bia is ON HOLD until Paper Publication

	Authors: Hettle, A.G., Boraston, A.B.		Authors: Hettle, A.G., Boraston, A.B.

OCA: Protected "6bia" [edit=sysop:move=sysop]

2017-11-08T06:37:50Z

Protected "6bia" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:37, 8 November 2017

OCA: New page: '''Unreleased structure''' The entry 6bia is ON HOLD Authors: Hettle, A.G., Boraston, A.B. Description: Crystal structure of Ps i-CgsB Category: Unreleased Structures [[Category: B...

2017-11-08T06:37:49Z

New page: '''Unreleased structure''' The entry 6bia is ON HOLD Authors: Hettle, A.G., Boraston, A.B. Description: Crystal structure of Ps i-CgsB Category: Unreleased Structures [[Category: B...

New page

'''Unreleased structure'''

The entry 6bia is ON HOLD

Authors: Hettle, A.G., Boraston, A.B.

Description: Crystal structure of Ps i-CgsB
[[Category: Unreleased Structures]]
[[Category: Boraston, A.B]]
[[Category: Hettle, A.G]]