6c2n - Revision history

OCA at 14:55, 4 October 2023

2023-10-04T14:55:05Z

←Older revision		Revision as of 14:55, 4 October 2023
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	<StructureSection load='6c2n' size='340' side='right'caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='6c2n' size='340' side='right'caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Hepatitis_c_virus_subtype_1a~~ Hepatitis c virus ~~subtype~~ 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6C2N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C2N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.802Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [~~http~~://pdbe.org/6c2n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [https://pdbe.org/6c2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [https://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC]
		+
		+	==See Also==
		+	*[[Virus protease 3D structures\|Virus protease 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hepatitis c virus ~~subtype~~ 1a]]	+	[[Category: Hepatitis C virus genotype 1a]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Matthew~~, A N~~]]	+	[[Category: Matthew AN]]
-	[[Category: Schiffer~~, C A]]~~	+	[[Category: Schiffer CA]]
-	~~[[Category: Drug resistance]]~~	+
-	~~[[Category: Hepatitis c virus]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Ns3/4a protease]]~~	+
-	~~[[Category: Protease inhibitor~~]]	+

OCA at 09:29, 18 December 2019

2019-12-18T09:29:16Z

←Older revision		Revision as of 09:29, 18 December 2019
Line 1:		Line 1:

	==Crystal structure of HCV NS3/4A double mutant variant Y56H/D168A in complex with danoprevir==		==Crystal structure of HCV NS3/4A double mutant variant Y56H/D168A in complex with danoprevir==
-	<StructureSection load='6c2n' size='340' side='right' caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='6c2n' size='340' side='right'caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>		<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>
Line 10:		Line 10:
	</StructureSection>		</StructureSection>
	[[Category: Hepatitis c virus subtype 1a]]		[[Category: Hepatitis c virus subtype 1a]]
		+	[[Category: Large Structures]]
	[[Category: Matthew, A N]]		[[Category: Matthew, A N]]
	[[Category: Schiffer, C A]]		[[Category: Schiffer, C A]]

OCA at 08:11, 21 February 2019

2019-02-21T08:11:06Z

←Older revision		Revision as of 08:11, 21 February 2019
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	<StructureSection load='6c2n' size='340' side='right' caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='6c2n' size='340' side='right' caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [http://pdbe.org/6c2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [http://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [http://pdbe.org/6c2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [http://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>
Line 9:		Line 9:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Hepatitis c virus subtype 1a]]
	[[Category: Matthew, A N]]		[[Category: Matthew, A N]]
	[[Category: Schiffer, C A]]		[[Category: Schiffer, C A]]

OCA at 12:03, 16 January 2019

2019-01-16T12:03:23Z

←Older revision		Revision as of 12:03, 16 January 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6c2n is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of HCV NS3/4A double mutant variant Y56H/D168A in complex with danoprevir==
-		+	<StructureSection load='6c2n' size='340' side='right' caption='[[6c2n]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [http://pdbe.org/6c2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [http://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Matthew, A N]]
		+	[[Category: Schiffer, C A]]
		+	[[Category: Drug resistance]]
		+	[[Category: Hepatitis c virus]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Ns3/4a protease]]
		+	[[Category: Protease inhibitor]]

OCA at 04:45, 31 January 2018

2018-01-31T04:45:27Z

←Older revision		Revision as of 04:45, 31 January 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6c2n is ON HOLD	+	The entry 6c2n is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6c2n" [edit=sysop:move=sysop]

2018-01-17T05:44:03Z

Protected "6c2n" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:44, 17 January 2018

OCA: New page: '''Unreleased structure''' The entry 6c2n is ON HOLD Authors: Description: Category: Unreleased Structures

2018-01-17T05:44:02Z

New page: '''Unreleased structure''' The entry 6c2n is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6c2n is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]