6emm - Revision history

OCA at 08:13, 3 April 2019

2019-04-03T08:13:14Z

←Older revision		Revision as of 08:13, 3 April 2019
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	==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid==		==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid==
-	<StructureSection load='6emm' size='340' side='right' caption='[[6emm]], [[Resolution\|resolution]] 2.47Å' scene=''>	+	<StructureSection load='6emm' size='340' side='right'caption='[[6emm]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6emm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EMM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6emm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EMM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSD17B14, DHRS10, SDR3, SDR47C1, UNQ502/PRO474 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6emm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6emm OCA], [http://pdbe.org/6emm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6emm RCSB], [http://www.ebi.ac.uk/pdbsum/6emm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6emm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6emm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6emm OCA], [http://pdbe.org/6emm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6emm RCSB], [http://www.ebi.ac.uk/pdbsum/6emm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6emm ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Bertoletti, N]]		[[Category: Bertoletti, N]]
	[[Category: Heine, A]]		[[Category: Heine, A]]

OCA at 06:52, 31 October 2018

2018-10-31T06:52:01Z

←Older revision		Revision as of 06:52, 31 October 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6emm ~~is ON HOLD~~	+	==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid==
-		+	<StructureSection load='6emm' size='340' side='right' caption='[[6emm]], [[Resolution\|resolution]] 2.47Å' scene=''>
-	~~Authors~~: ~~Bertoletti~~, N., ~~Marchais~~-~~Oberwinkler~~, S., ~~Heine, A~~., ~~Klebe~~, G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6emm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EMM FirstGlance]. <br>
-	~~Description: 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6emm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6emm OCA], [http://pdbe.org/6emm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6emm RCSB], [http://www.ebi.ac.uk/pdbsum/6emm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6emm ProSAT]</span></td></tr>
-	[[Category: ~~Marchais-Oberwinkler~~, S]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DHB14_HUMAN DHB14_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bertoletti, N]]
	[[Category: Heine, A]]		[[Category: Heine, A]]
-	[[Category: Bertoletti, N]]
	[[Category: Klebe, G]]		[[Category: Klebe, G]]
		+	[[Category: Marchais-Oberwinkler, S]]
		+	[[Category: 17b-hsd14]]
		+	[[Category: Fragment]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Soaking]]

OCA: Protected "6emm" [edit=sysop:move=sysop]

2017-10-11T05:43:57Z

Protected "6emm" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:43, 11 October 2017

OCA: New page: '''Unreleased structure''' The entry 6emm is ON HOLD Authors: Bertoletti, N., Marchais-Oberwinkler, S., Heine, A., Klebe, G. Description: 17beta-hydroxysteroid dehydrogenase 14 variant...

2017-10-11T05:43:56Z

New page: '''Unreleased structure''' The entry 6emm is ON HOLD Authors: Bertoletti, N., Marchais-Oberwinkler, S., Heine, A., Klebe, G. Description: 17beta-hydroxysteroid dehydrogenase 14 variant...

New page

'''Unreleased structure'''

The entry 6emm is ON HOLD

Authors: Bertoletti, N., Marchais-Oberwinkler, S., Heine, A., Klebe, G.

Description: 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid
[[Category: Unreleased Structures]]
[[Category: Marchais-Oberwinkler, S]]
[[Category: Heine, A]]
[[Category: Bertoletti, N]]
[[Category: Klebe, G]]