OCA at 07:31, 22 February 2018

2018-02-22T07:31:06Z

←Older revision		Revision as of 07:31, 22 February 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6etn is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Atomic resolution structure of RNase A (data collection 4)==
		+	<StructureSection load='6etn' size='340' side='right' caption='[[6etn]], [[Resolution\|resolution]] 0.92Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6etn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ETN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ETN FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6etn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6etn OCA], [http://pdbe.org/6etn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6etn RCSB], [http://www.ebi.ac.uk/pdbsum/6etn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6etn ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Despite their high relevance, the mechanisms of X-ray radiation damage on protein structure yet have to be completely established. Here, we used Raman microspectrophotometry to follow X-ray-induced chemical modifications on the structure of the model protein bovine pancreatic ribonuclease (RNase A). The combination of dose-dependent Raman spectra and ultrahigh resolution (eight structures solved using data collected between 0.85 and 1.17A resolution on the same single crystal) allowed direct observation of several radiation damage events, including covalent bond breakages and formation of radicals. Our results are relevant for analytical photodamage detection and provide implications for a detailed understanding of the mechanisms of photoproduct formation.

-	~~Authors: Caterino, M~~., Vergara, A., ~~Merlino~~, A.	+	Raman-markers of X-ray radiation damage of proteins.,Vergara A, Caterino M, Merlino A Int J Biol Macromol. 2018 Feb 2;111:1194-1205. doi:, 10.1016/j.ijbiomac.2018.01.135. PMID:29374529<ref>PMID:29374529</ref>

-	~~Description: Atomic resolution structure~~ of ~~RNase A (data collection 4)~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	[[Category: ~~Vergara, A~~]]	+	<div class="pdbe-citations 6etn" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Merlino, A~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bos taurus]]
		+	[[Category: Pancreatic ribonuclease]]
	[[Category: Caterino, M]]		[[Category: Caterino, M]]
		+	[[Category: Merlino, A]]
		+	[[Category: Vergara, A]]
		+	[[Category: Atomic resolution]]
		+	[[Category: Hydrolase]]
		+	[[Category: Photodamage]]
		+	[[Category: Radiation damage]]
		+	[[Category: Raman microspectroscopy]]
		+	[[Category: Ribonuclease]]

OCA at 06:41, 8 November 2017

2017-11-08T06:41:13Z

←Older revision		Revision as of 06:41, 8 November 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6etn is ON HOLD	+	The entry 6etn is ON HOLD until Paper Publication

	Authors: Caterino, M., Vergara, A., Merlino, A.		Authors: Caterino, M., Vergara, A., Merlino, A.

OCA: Protected "6etn" [edit=sysop:move=sysop]

2017-11-01T05:08:39Z

Protected "6etn" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:08, 1 November 2017

OCA: New page: '''Unreleased structure''' The entry 6etn is ON HOLD Authors: Caterino, M., Vergara, A., Merlino, A. Description: Atomic resolution structure of RNase A (data collection 4) [[Category:...

2017-11-01T05:08:38Z

New page: '''Unreleased structure''' The entry 6etn is ON HOLD Authors: Caterino, M., Vergara, A., Merlino, A. Description: Atomic resolution structure of RNase A (data collection 4) [[Category:...

New page

'''Unreleased structure'''

The entry 6etn is ON HOLD

Authors: Caterino, M., Vergara, A., Merlino, A.

Description: Atomic resolution structure of RNase A (data collection 4)
[[Category: Unreleased Structures]]
[[Category: Vergara, A]]
[[Category: Merlino, A]]
[[Category: Caterino, M]]

6etn - Revision history

OCA at 07:31, 22 February 2018

OCA at 06:41, 8 November 2017

OCA: Protected "6etn" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6etn is ON HOLD Authors: Caterino, M., Vergara, A., Merlino, A. Description: Atomic resolution structure of RNase A (data collection 4) [[Category:...