6fub - Revision history

OCA at 09:50, 18 July 2018

2018-07-18T09:50:01Z

←Older revision		Revision as of 09:50, 18 July 2018
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	<StructureSection load='6fub' size='340' side='right' caption='[[6fub]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='6fub' size='340' side='right' caption='[[6fub]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6fub]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FUB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6fub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpi_841383 Bpi 841383] and [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FUB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fu9\|6fu9]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fu9\|6fu9]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AVR-Pik ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=318829 BPI 841383]), Pikm1-TS, Pi-km1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fub OCA], [http://pdbe.org/6fub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fub RCSB], [http://www.ebi.ac.uk/pdbsum/6fub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fub ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fub OCA], [http://pdbe.org/6fub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fub RCSB], [http://www.ebi.ac.uk/pdbsum/6fub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fub ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Accelerated adaptive evolution is a hallmark of plant-pathogen interactions. Plant intracellular immune receptors (NLRs) often occur as allelic series with differential pathogen specificities. The determinants of this specificity remain largely unknown. Here, we unravelled the biophysical and structural basis of expanded specificity in the allelic rice NLR Pik, which responds to the effector AVR-Pik from the rice blast pathogen Magnaporthe oryzae. Rice plants expressing the Pikm allele resist infection by blast strains expressing any of three AVR-Pik effector variants, whereas those expressing Pikp only respond to one. Unlike Pikp, the integrated heavy metal-associated (HMA) domain of Pikm binds with high affinity to each of the three recognized effector variants, and variation at binding interfaces between effectors and Pikp-HMA or Pikm-HMA domains encodes specificity. By understanding how co-evolution has shaped the response profile of an allelic NLR, we highlight how natural selection drove the emergence of new receptor specificities. This work has implications for the engineering of NLRs with improved utility in agriculture.
		+
		+	Polymorphic residues in rice NLRs expand binding and response to effectors of the blast pathogen.,De la Concepcion JC, Franceschetti M, Maqbool A, Saitoh H, Terauchi R, Kamoun S, Banfield MJ Nat Plants. 2018 Jul 9. pii: 10.1038/s41477-018-0194-x. doi:, 10.1038/s41477-018-0194-x. PMID:29988155<ref>PMID:29988155</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6fub" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpi 841383]]
		+	[[Category: Japanese rice]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Concepcion, J C.De la]]		[[Category: Concepcion, J C.De la]]

OCA at 07:42, 14 June 2018

2018-06-14T07:42:39Z

←Older revision		Revision as of 07:42, 14 June 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6fub is ~~ON HOLD until Paper Publication~~	+	==Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikE with the HMA domain of Pikm-1 from rice (Oryza sativa)==
-		+	<StructureSection load='6fub' size='340' side='right' caption='[[6fub]], [[Resolution\|resolution]] 1.30Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6fub]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FUB FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fu9\|6fu9]]</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fub OCA], [http://pdbe.org/6fub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fub RCSB], [http://www.ebi.ac.uk/pdbsum/6fub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fub ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Banfield, M J]]
		+	[[Category: Concepcion, J C.De la]]
		+	[[Category: Franceschetti, M]]
		+	[[Category: Antifungal protein]]
		+	[[Category: Complex]]
		+	[[Category: Fungal effector]]
		+	[[Category: Plant immunity]]
		+	[[Category: Plant nlr]]

OCA: Protected "6fub" [edit=sysop:move=sysop]

2018-03-08T03:57:26Z

Protected "6fub" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:57, 8 March 2018

OCA: New page: '''Unreleased structure''' The entry 6fub is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

2018-03-08T03:57:25Z

New page: '''Unreleased structure''' The entry 6fub is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6fub is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]