6gxs - Revision history

OCA at 05:43, 13 May 2020

2020-05-13T05:43:08Z

←Older revision		Revision as of 05:43, 13 May 2020
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	<StructureSection load='6gxs' size='340' side='right'caption='[[6gxs]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='6gxs' size='340' side='right'caption='[[6gxs]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gxs]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GXS OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6GXS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gxs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrvo Chrvo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GXS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GXS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6gxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gxs OCA], [http://pdbe.org/6gxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gxs RCSB], [http://www.ebi.ac.uk/pdbsum/6gxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gxs ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CV_1052 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243365 CHRVO])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gxs OCA], [http://pdbe.org/6gxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gxs RCSB], [http://www.ebi.ac.uk/pdbsum/6gxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gxs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chrvo]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bovin, N]]		[[Category: Bovin, N]]

OCA at 07:55, 4 December 2019

2019-12-04T07:55:16Z

←Older revision		Revision as of 07:55, 4 December 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6gxs is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of CV39L lectin from Chromobacterium violaceum at 1.8 A resolution==
		+	<StructureSection load='6gxs' size='340' side='right'caption='[[6gxs]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6gxs]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GXS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gxs OCA], [http://pdbe.org/6gxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gxs RCSB], [http://www.ebi.ac.uk/pdbsum/6gxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gxs ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Burkholderia pseudomallei and Chromobacterium violaceum are bacteria of tropical and subtropical soil and water that occasionally cause fatal infections in humans and animals. Microbial lectins mediate the adhesion of organisms to host cells, which is the first phase in the development of infection. Here we report the discovery of two novel lectins from the above-mentioned bacteria - BP39L and CV39L. The crystal structures revealed that the lectins possess a seven-bladed beta-propeller fold. Functional studies conducted on a series of oligo- and polysaccharides confirmed the preference of BP39L for mannosylated saccharides and CV39L for rather more complex polysaccharides with a monosaccharide preference for beta-L-fucose. The presented data indicate that the proteins belong to a currently unknown family of lectins.

-	~~Authors:~~ Sykorova, P., Novotna, J., Demo, G., Pompidor, G., Dubska, E., Komarek, J., Fujdiarova, E., Haronikova, L., Varrot, A., Imberty, A~~., Shilova, N.~~, Bovin, N., Pokorna, M., Wimmerova, M.	+	Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold.,Sykorova P, Novotna J, Demo G, Pompidor G, Dubska E, Komarek J, Fujdiarova E, Houser J, Haronikova L, Varrot A, Shilova N, Imberty A, Bovin N, Pokorna M, Wimmerova M Int J Biol Macromol. 2019 Nov 18. pii: S0141-8130(19)33609-8. doi:, 10.1016/j.ijbiomac.2019.10.200. PMID:31751748<ref>PMID:31751748</ref>

-	~~Description: Crystal structure~~ of ~~CV39L lectin from Chromobacterium violaceum at 1~~.~~8 A resolution~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Novotna, J]]~~	+	<div class="pdbe-citations 6gxs" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Wimmerova, M~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bovin, N]]		[[Category: Bovin, N]]
	[[Category: Demo, G]]		[[Category: Demo, G]]
	[[Category: Dubska, E]]		[[Category: Dubska, E]]
-	[[Category: ~~Komarek~~, ~~J]]~~	+	[[Category: Fujdiarova, E]]
-	~~[[Category: Sykorova, P]]~~	+
-	~~[[Category: Varrot, A~~]]	+
	[[Category: Haronikova, L]]		[[Category: Haronikova, L]]
-	[[Category: ~~Pompidor~~, G]]	+	[[Category: Imberty, A]]
		+	[[Category: Komarek, J]]
		+	[[Category: Novotna, J]]
	[[Category: Pokorna, M]]		[[Category: Pokorna, M]]
-	[[Category: ~~Fujdiarova~~, E]]	+	[[Category: Pompidor, G]]
	[[Category: Shilova, N]]		[[Category: Shilova, N]]
-	[[Category: ~~Imberty~~, A]]	+	[[Category: Sykorova, P]]
		+	[[Category: Varrot, A]]
		+	[[Category: Wimmerova, M]]
		+	[[Category: Lectin]]
		+	[[Category: Sugar binding protein]]

OCA: Protected "6gxs" [edit=sysop:move=sysop]

2018-07-04T05:57:46Z

Protected "6gxs" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:57, 4 July 2018

OCA: New page: '''Unreleased structure''' The entry 6gxs is ON HOLD until Paper Publication Authors: Sykorova, P., Novotna, J., Demo, G., Pompidor, G., Dubska, E., Komarek, J., Fujdiarova, E., Haronik...

2018-07-04T05:57:45Z

New page: '''Unreleased structure''' The entry 6gxs is ON HOLD until Paper Publication Authors: Sykorova, P., Novotna, J., Demo, G., Pompidor, G., Dubska, E., Komarek, J., Fujdiarova, E., Haronik...

New page

'''Unreleased structure'''

The entry 6gxs is ON HOLD until Paper Publication

Authors: Sykorova, P., Novotna, J., Demo, G., Pompidor, G., Dubska, E., Komarek, J., Fujdiarova, E., Haronikova, L., Varrot, A., Imberty, A., Shilova, N., Bovin, N., Pokorna, M., Wimmerova, M.

Description: Crystal structure of CV39L lectin from Chromobacterium violaceum at 1.8 A resolution
[[Category: Unreleased Structures]]
[[Category: Novotna, J]]
[[Category: Wimmerova, M]]
[[Category: Bovin, N]]
[[Category: Demo, G]]
[[Category: Dubska, E]]
[[Category: Komarek, J]]
[[Category: Sykorova, P]]
[[Category: Varrot, A]]
[[Category: Haronikova, L]]
[[Category: Pompidor, G]]
[[Category: Pokorna, M]]
[[Category: Fujdiarova, E]]
[[Category: Shilova, N]]
[[Category: Imberty, A]]