6ijz - Revision history

OCA at 10:33, 27 March 2024

2024-03-27T10:33:42Z

←Older revision		Revision as of 10:33, 27 March 2024
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	<SX load='6ijz' size='340' side='right' viewer='molstar' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>		<SX load='6ijz' size='340' side='right' viewer='molstar' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ijz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijz OCA], [~~http~~://pdbe.org/6ijz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ijz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ijz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijz ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.68Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ijz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijz OCA], [https://pdbe.org/6ijz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ijz RCSB], [https://www.ebi.ac.uk/pdbsum/6ijz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CSC1_ARATH CSC1_ARATH]] Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent.<ref>PMID:24503647</ref>	+	[https://www.uniprot.org/uniprot/CSC1_ARATH CSC1_ARATH] Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent.<ref>PMID:24503647</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	In plants, hyperosmolality stimuli triggers opening of the osmosensitive channels, leading to a rapid downstream signaling cascade initiated by cytosolic calcium concentration elevation. Members of the OSCA family in Arabidopsis thaliana, identified as the hyperosmolality-gated calcium-permeable channels, have been suggested to play a key role during the initial phase of hyperosmotic stress response. Here, we report the atomic structure of Arabidopsis OSCA1.2 determined by single-particle cryo-electron microscopy. It contains 11 transmembrane helices and forms a homodimer. It is in an inactivated state, and the pore-lining residues are clearly identified. Its cytosolic domain contains a RNA recognition motif and two unique long helices. The linker between these two helices forms an anchor in the lipid bilayer and may be essential to osmosensing. The structure of AtOSCA1.2 serves as a platform for the study of the mechanism underlying osmotic stress responses and mechanosensing.	+
-		+
-	~~Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2.,Liu X, Wang J, Sun L Nat Commun. 2018 Nov 29;9(1):5060. doi: 10.1038/s41467-018-07564-5. PMID:30498218<ref>PMID:30498218</ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6ijz" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
Line 24:		Line 16:
	__TOC__		__TOC__
	</SX>		</SX>
		+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Liu, X]]	+	[[Category: Liu X]]
-	[[Category: Sun, L]]	+	[[Category: Sun L]]
-	[[Category: Wang, J]]	+	[[Category: Wang J]]
-	~~[[Category: Channel]]~~	+
-	~~[[Category: Membrane protein~~]]	+

OCA at 01:47, 11 April 2020

2020-04-11T01:47:19Z

←Older revision		Revision as of 01:47, 11 April 2020
Line 3:		Line 3:
	<SX load='6ijz' size='340' side='right' viewer='molstar' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>		<SX load='6ijz' size='340' side='right' viewer='molstar' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ijz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijz OCA], [http://pdbe.org/6ijz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijz RCSB], [http://www.ebi.ac.uk/pdbsum/6ijz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijz ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ijz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijz OCA], [http://pdbe.org/6ijz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijz RCSB], [http://www.ebi.ac.uk/pdbsum/6ijz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 22:08, 6 March 2020

2020-03-06T22:08:57Z

←Older revision		Revision as of 22:08, 6 March 2020
Line 1:		Line 1:

	==Structure of a plant cation channel==		==Structure of a plant cation channel==
-	<~~StructureSection~~ load='6ijz' size='340' side='right' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>	+	<SX load='6ijz' size='340' side='right' viewer='molstar' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 6ijz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6ijz" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ion channels 3D structures\|Ion channels 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Liu, X]]		[[Category: Liu, X]]
	[[Category: Sun, L]]		[[Category: Sun, L]]

OCA at 06:55, 12 December 2018

2018-12-12T06:55:40Z

←Older revision		Revision as of 06:55, 12 December 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6ijz is ~~ON HOLD~~	+	==Structure of a plant cation channel==
		+	<StructureSection load='6ijz' size='340' side='right' caption='[[6ijz]], [[Resolution\|resolution]] 3.68Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6ijz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJZ FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ijz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijz OCA], [http://pdbe.org/6ijz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijz RCSB], [http://www.ebi.ac.uk/pdbsum/6ijz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijz ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CSC1_ARATH CSC1_ARATH]] Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent.<ref>PMID:24503647</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In plants, hyperosmolality stimuli triggers opening of the osmosensitive channels, leading to a rapid downstream signaling cascade initiated by cytosolic calcium concentration elevation. Members of the OSCA family in Arabidopsis thaliana, identified as the hyperosmolality-gated calcium-permeable channels, have been suggested to play a key role during the initial phase of hyperosmotic stress response. Here, we report the atomic structure of Arabidopsis OSCA1.2 determined by single-particle cryo-electron microscopy. It contains 11 transmembrane helices and forms a homodimer. It is in an inactivated state, and the pore-lining residues are clearly identified. Its cytosolic domain contains a RNA recognition motif and two unique long helices. The linker between these two helices forms an anchor in the lipid bilayer and may be essential to osmosensing. The structure of AtOSCA1.2 serves as a platform for the study of the mechanism underlying osmotic stress responses and mechanosensing.

-	~~Authors~~:	+	Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2.,Liu X, Wang J, Sun L Nat Commun. 2018 Nov 29;9(1):5060. doi: 10.1038/s41467-018-07564-5. PMID:30498218<ref>PMID:30498218</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6ijz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Liu, X]]
		+	[[Category: Sun, L]]
		+	[[Category: Wang, J]]
		+	[[Category: Channel]]
		+	[[Category: Membrane protein]]

OCA: Protected "6ijz" [edit=sysop:move=sysop]

2018-10-24T04:20:09Z

Protected "6ijz" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:20, 24 October 2018

OCA: New page: '''Unreleased structure''' The entry 6ijz is ON HOLD Authors: Description: Category: Unreleased Structures

2018-10-24T04:20:07Z

New page: '''Unreleased structure''' The entry 6ijz is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ijz is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]