6ipa - Revision history

OCA at 09:48, 22 November 2023

2023-11-22T09:48:47Z

←Older revision		Revision as of 09:48, 22 November 2023
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	<StructureSection load='6ipa' size='340' side='right'caption='[[6ipa]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='6ipa' size='340' side='right'caption='[[6ipa]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ipa]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Haemamoeba_vivax Haemamoeba~~ vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IPA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6IPA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ipa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IPA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ipa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ipa OCA], [~~http~~://pdbe.org/6ipa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ipa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ipa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ipa ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.47Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ipa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ipa OCA], [https://pdbe.org/6ipa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ipa RCSB], [https://www.ebi.ac.uk/pdbsum/6ipa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ipa ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A5K3Y7_PLAVS A5K3Y7_PLAVS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Haemamoeba vivax]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gupta, S]]	+	[[Category: Plasmodium vivax]]
-	[[Category: Harlos, K]]	+	[[Category: Gupta S]]
-	[[Category: Manickam, Y]]	+	[[Category: Harlos K]]
-	[[Category: Sharma, A]]	+	[[Category: Manickam Y]]
-	~~[[Category: Aimp1]]~~	+	[[Category: Sharma A]]
-	~~[[Category: Emapii-like domain]]~~	+
-	~~[[Category: Plasmodium]]~~	+
-	~~[[Category: Rna binding protein~~]]	+

OCA at 07:51, 11 March 2020

2020-03-11T07:51:49Z

←Older revision		Revision as of 07:51, 11 March 2020
Line 3:		Line 3:
	<StructureSection load='6ipa' size='340' side='right'caption='[[6ipa]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='6ipa' size='340' side='right'caption='[[6ipa]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ipa]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IPA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IPA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ipa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemamoeba_vivax Haemamoeba vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IPA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IPA FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ipa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ipa OCA], [http://pdbe.org/6ipa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ipa RCSB], [http://www.ebi.ac.uk/pdbsum/6ipa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ipa ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ipa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ipa OCA], [http://pdbe.org/6ipa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ipa RCSB], [http://www.ebi.ac.uk/pdbsum/6ipa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ipa ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Scaffold modules known as aminoacyl-tRNA synthetase (aaRS)-interacting multifunctional proteins (AIMPs), such as AIMP1/p43, AIMP2/p38 and AIMP3/p18, are important in driving the assembly of multi-aaRS (MARS) complexes in eukaryotes. Often, AIMPs contain an N-terminal glutathione S-transferase (GST)-like domain and a C-terminal OB-fold tRNA-binding domain. Recently, the apicomplexan-specific Plasmodium falciparum p43 protein (Pfp43) has been annotated as an AIMP and its tRNA binding, tRNA import and membrane association have been characterized. The crystal structures of both the N- and C-terminal domains of the Plasmodium vivax p43 protein (Pvp43), which is an ortholog of Pfp43, have been resolved. Analyses reveal the overall oligomeric structure of Pvp43 and highlight several notable features that show Pvp43 to be a soluble, cytosolic protein. The dimeric assembly of the N-terminal GST-like domain of Pvp43 differs significantly from canonical GST dimers, and it is tied to the C-terminal tRNA-binding domain via a linker region. This work therefore establishes a framework for dissecting the additional roles of p43 orthologs in eukaryotic multi-protein MARS complexes.
		+
		+	Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.,Gupta S, Chhibber-Goel J, Sharma M, Parvez S, Harlos K, Sharma A, Yogavel M Acta Crystallogr D Struct Biol. 2020 Feb 1;76(Pt 2):135-146. doi:, 10.1107/S2059798319016413. Epub 2020 Jan 30. PMID:32038044<ref>PMID:32038044</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6ipa" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Haemamoeba vivax]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gupta, S]]		[[Category: Gupta, S]]

OCA at 06:36, 6 November 2019

2019-11-06T06:36:21Z

←Older revision		Revision as of 06:36, 6 November 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6ipa ~~is ON HOLD until Paper Publication~~	+	==C-terminal EMAP II-like domain of p43 refined against twinned data==
-		+	<StructureSection load='6ipa' size='340' side='right'caption='[[6ipa]], [[Resolution\|resolution]] 2.47Å' scene=''>
-	~~Authors~~: ~~Manickam~~, Y., ~~Harlos~~, K., ~~Gupta, S~~., ~~Sharma, A~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6ipa]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IPA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IPA FirstGlance]. <br>
-	~~Description: C-terminal EMAP II-like domain of p43 refined against twinned data~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ipa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ipa OCA], [http://pdbe.org/6ipa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ipa RCSB], [http://www.ebi.ac.uk/pdbsum/6ipa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ipa ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Gupta, S]]
	[[Category: Harlos, K]]		[[Category: Harlos, K]]
-	[[Category: ~~Gupta~~, S]]	+	[[Category: Manickam, Y]]
	[[Category: Sharma, A]]		[[Category: Sharma, A]]
-	[[Category: ~~Manickam, Y~~]]	+	[[Category: Aimp1]]
		+	[[Category: Emapii-like domain]]
		+	[[Category: Plasmodium]]
		+	[[Category: Rna binding protein]]

OCA at 18:51, 2 December 2018

2018-12-02T18:51:29Z

←Older revision		Revision as of 18:51, 2 December 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ipa is ON HOLD	+	The entry 6ipa is ON HOLD until Paper Publication

-	Authors: Manickam, Y., Gupta, S., Sharma, A.	+	Authors: Manickam, Y., Harlos, K., Gupta, S., Sharma, A.

	Description: C-terminal EMAP II-like domain of p43 refined against twinned data		Description: C-terminal EMAP II-like domain of p43 refined against twinned data
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Harlos, K]]
	[[Category: Gupta, S]]		[[Category: Gupta, S]]
	[[Category: Sharma, A]]		[[Category: Sharma, A]]
	[[Category: Manickam, Y]]		[[Category: Manickam, Y]]

OCA at 06:29, 14 November 2018

2018-11-14T06:29:16Z

←Older revision		Revision as of 06:29, 14 November 2018
Line 5:		Line 5:
	Authors: Manickam, Y., Gupta, S., Sharma, A.		Authors: Manickam, Y., Gupta, S., Sharma, A.

-	Description: C-~~TERMINAL~~ EMAP II-~~LIKE DOMAIN~~ of p43 refined against twinned data	+	Description: C-terminal EMAP II-like domain of p43 refined against twinned data
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Manickam, Y]]
	[[Category: Gupta, S]]		[[Category: Gupta, S]]
	[[Category: Sharma, A]]		[[Category: Sharma, A]]
		+	[[Category: Manickam, Y]]

OCA: Protected "6ipa" [edit=sysop:move=sysop]

2018-11-07T10:46:40Z

Protected "6ipa" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:46, 7 November 2018

OCA: New page: '''Unreleased structure''' The entry 6ipa is ON HOLD Authors: Manickam, Y., Gupta, S., Sharma, A. Description: C-TERMINAL EMAP II-LIKE DOMAIN of p43 refined against twinned data [[Cate...

2018-11-07T10:46:39Z

New page: '''Unreleased structure''' The entry 6ipa is ON HOLD Authors: Manickam, Y., Gupta, S., Sharma, A. Description: C-TERMINAL EMAP II-LIKE DOMAIN of p43 refined against twinned data [[Cate...

New page

'''Unreleased structure'''

The entry 6ipa is ON HOLD

Authors: Manickam, Y., Gupta, S., Sharma, A.

Description: C-TERMINAL EMAP II-LIKE DOMAIN of p43 refined against twinned data
[[Category: Unreleased Structures]]
[[Category: Manickam, Y]]
[[Category: Gupta, S]]
[[Category: Sharma, A]]