6iwn - Revision history

OCA at 09:54, 22 November 2023

2023-11-22T09:54:29Z

←Older revision		Revision as of 09:54, 22 November 2023
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	<StructureSection load='6iwn' size='340' side='right'caption='[[6iwn]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='6iwn' size='340' side='right'caption='[[6iwn]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6iwn]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Solanum_melongena Solanum melongena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6IWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6iwn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_melongena Solanum melongena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IWN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.408Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6iwm\|6iwm]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [~~http~~://pdbe.org/6iwn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [https://pdbe.org/6iwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [https://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A247D6Y2_SOLME A0A247D6Y2_SOLME]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Solanum melongena]]		[[Category: Solanum melongena]]
-	[[Category: Madni~~, Z K~~]]	+	[[Category: Madni ZK]]
-	[[Category: Salunke~~, D M]]~~	+	[[Category: Salunke DM]]
-	~~[[Category: Lipid transfer protein]]~~	+
-	~~[[Category: Lipid transport]]~~	+
-	~~[[Category: Myristic acid]]~~	+
-	~~[[Category: Nsltp~~]]	+

OCA at 05:43, 13 May 2020

2020-05-13T05:43:52Z

←Older revision		Revision as of 05:43, 13 May 2020
Line 3:		Line 3:
	<StructureSection load='6iwn' size='340' side='right'caption='[[6iwn]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='6iwn' size='340' side='right'caption='[[6iwn]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6iwn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_melongena Solanum melongena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6IWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6iwn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_melongena Solanum melongena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6IWN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6iwm\|6iwm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6iwm\|6iwm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [http://pdbe.org/6iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [http://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [http://pdbe.org/6iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [http://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:56, 25 December 2019

2019-12-25T12:56:48Z

←Older revision		Revision as of 12:56, 25 December 2019
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [http://pdbe.org/6iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [http://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [http://pdbe.org/6iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [http://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The non-specific lipid transfer proteins (nsLTPs) are multifunctional seed proteins engaged in several different physiological processes. The nsLTPs are stabilized by four disulfide bonds and exhibit a characteristic hydrophobic cavity, which is the primary lipid binding site. While these proteins are known to transfer lipids between membranes, the mechanism of lipid transfer has remained elusive. Four crystal structures of nsLTP from S. melongena, one in the apo-state and three myristic acid bound states were determined. Among the three lipid bound states, two lipid molecules were bound on the nsLTP surface at different positions and one was inside the cavity. The lipid dependent conformational changes leading to opening of the cavity were revealed based on structural and spectroscopic data. The surface bound lipid represented a transient intermediate state and the lipid ultimately moved inside the cavity through the cavity gate as revealed by molecular dynamics simulations. Two critical residues in the loop regions played possible 'gating' role in the opening and closing of the cavity. Anti-fungal activity and membrane permeabilization effect of nsLTP against Fusarium oxysporum suggested that it could possibly involve in bleaching out the lipids. Collectively, these studies support a model of lipid transfer mechanism by nsLTP via intermediate states.
		+
		+	Structural insights into the lipid transfer mechanism of a non-specific lipid transfer protein.,Madni ZK, Tripathi SK, Salunke DM Plant J. 2019 Dec 2. doi: 10.1111/tpj.14627. PMID:31793077<ref>PMID:31793077</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6iwn" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 15:02, 11 December 2019

2019-12-11T15:02:51Z

←Older revision		Revision as of 15:02, 11 December 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6iwn ~~is ON HOLD until Dec 05 2020~~	+	==Structural insight into probable lipid transfer mechanism of non-specific lipid transfer protein via intermediate structures in Solanum melongena==
-		+	<StructureSection load='6iwn' size='340' side='right'caption='[[6iwn]], [[Resolution\|resolution]] 2.41Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6iwn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_melongena Solanum melongena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IWN FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6iwm\|6iwm]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iwn OCA], [http://pdbe.org/6iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iwn RCSB], [http://www.ebi.ac.uk/pdbsum/6iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iwn ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Solanum melongena]]
		+	[[Category: Madni, Z K]]
		+	[[Category: Salunke, D M]]
		+	[[Category: Lipid transfer protein]]
		+	[[Category: Lipid transport]]
		+	[[Category: Myristic acid]]
		+	[[Category: Nsltp]]

OCA at 06:37, 26 December 2018

2018-12-26T06:37:08Z

←Older revision		Revision as of 06:37, 26 December 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6iwn is ON HOLD	+	The entry 6iwn is ON HOLD until Dec 05 2020

	Authors:		Authors:

OCA: Protected "6iwn" [edit=sysop:move=sysop]

2018-12-12T05:16:00Z

Protected "6iwn" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:16, 12 December 2018

OCA: New page: '''Unreleased structure''' The entry 6iwn is ON HOLD Authors: Description: Category: Unreleased Structures

2018-12-12T05:15:59Z

New page: '''Unreleased structure''' The entry 6iwn is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6iwn is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]