6j90 - Revision history

OCA at 10:03, 22 November 2023

2023-11-22T10:03:45Z

←Older revision		Revision as of 10:03, 22 November 2023
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	<StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6j90]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6J90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6j90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J90 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gyrB, STY3943, t3684 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [https://pdbe.org/6j90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [https://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [~~http~~://pdbe.org/6j90 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GYRB_SALTI GYRB_SALTI]] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01898]	+	[https://www.uniprot.org/uniprot/GYRB_SALTI GYRB_SALTI] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01898]
		+
		+	==See Also==
		+	*[[Gyrase 3D Structures\|Gyrase 3D Structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus typhi schroeter 1886]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ethayathulla~~, A S~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhi]]
-	[[Category: Gupta, D]]	+	[[Category: Ethayathulla AS]]
-	[[Category: Kaur, G]]	+	[[Category: Gupta D]]
-	[[Category: Kaur, P]]	+	[[Category: Kaur G]]
-	[[Category: Sachdeva, E]]	+	[[Category: Kaur P]]
-	[[Category: Tiwari, P]]	+	[[Category: Sachdeva E]]
-	~~[[Category: Atpase protein]]~~	+	[[Category: Tiwari P]]
-	~~[[Category: Gyrb-ntd]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Topoisomerase~~]]	+

OCA at 16:08, 29 January 2020

2020-01-29T16:08:12Z

←Older revision		Revision as of 16:08, 29 January 2020
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	<StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6j90]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6j90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J90 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gyrB, STY3943, t3684 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [http://pdbe.org/6j90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [http://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [http://pdbe.org/6j90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [http://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus typhi schroeter 1886]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Ethayathulla, A S]]		[[Category: Ethayathulla, A S]]

OCA at 16:07, 22 January 2020

2020-01-22T16:07:33Z

←Older revision		Revision as of 16:07, 22 January 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6j90 ~~is ON HOLD until Paper Publication~~	+	==Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution==
-		+	<StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~Authors~~: ~~Kaur, G~~., ~~Sachdeva~~, E., ~~Tiwari~~, P., ~~Gupta~~, D., ~~Ethayathulla, A~~.S., ~~Kaur, P~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6j90]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J90 FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure of GyraseB N~~-~~Terminal Domain complex with~~ ATP ~~from Salmonella Typhi at~~ 2.~~2A Resolution~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [http://pdbe.org/6j90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [http://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GYRB_SALTI GYRB_SALTI]] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01898]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Ethayathulla, A S]]
	[[Category: Gupta, D]]		[[Category: Gupta, D]]
		+	[[Category: Kaur, G]]
		+	[[Category: Kaur, P]]
		+	[[Category: Sachdeva, E]]
	[[Category: Tiwari, P]]		[[Category: Tiwari, P]]
-	[[Category: ~~Ethayathulla, A.S~~]]	+	[[Category: Atpase protein]]
-	[[Category: ~~Sachdeva, E~~]]	+	[[Category: Gyrb-ntd]]
-	[[Category: ~~Kaur, P~~]]	+	[[Category: Isomerase]]
-	[[Category: ~~Kaur, G~~]]	+	[[Category: Topoisomerase]]

OCA at 09:58, 13 March 2019

2019-03-13T09:58:41Z

←Older revision		Revision as of 09:58, 13 March 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6j90 is ON HOLD	+	The entry 6j90 is ON HOLD until Paper Publication

	Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P.		Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P.

OCA: Protected "6j90" [edit=sysop:move=sysop]

2019-01-30T06:15:48Z

Protected "6j90" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:15, 30 January 2019

OCA: New page: '''Unreleased structure''' The entry 6j90 is ON HOLD Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P. Description: Crystal Structure of GyraseB N-Te...

2019-01-30T06:15:47Z

New page: '''Unreleased structure''' The entry 6j90 is ON HOLD Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P. Description: Crystal Structure of GyraseB N-Te...

New page

'''Unreleased structure'''

The entry 6j90 is ON HOLD

Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P.

Description: Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution
[[Category: Unreleased Structures]]
[[Category: Gupta, D]]
[[Category: Tiwari, P]]
[[Category: Ethayathulla, A.S]]
[[Category: Sachdeva, E]]
[[Category: Kaur, P]]
[[Category: Kaur, G]]