6klj - Revision history

OCA at 10:36, 22 November 2023

2023-11-22T10:36:36Z

←Older revision		Revision as of 10:36, 22 November 2023
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	<StructureSection load='6klj' size='340' side='right'caption='[[6klj]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='6klj' size='340' side='right'caption='[[6klj]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6klj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Maize Maize~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6KLJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6klj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KLJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIY:(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENAL'>CIY</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.998Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6klg\|6klg]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIY:(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENAL'>CIY</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lac3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 MAIZE])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klj OCA], [https://pdbe.org/6klj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6klj RCSB], [https://www.ebi.ac.uk/pdbsum/6klj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6klj ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klj OCA], [~~http~~://pdbe.org/6klj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6klj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6klj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6klj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/Q2PAJ1_MAIZE Q2PAJ1_MAIZE]] Lignin degradation and detoxification of lignin-derived products.[RuleBase:RU361119]	+	[https://www.uniprot.org/uniprot/Q2PAJ1_MAIZE Q2PAJ1_MAIZE] Lignin degradation and detoxification of lignin-derived products.[RuleBase:RU361119]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6klj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6klj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Laccase 3D structures\|Laccase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Laccase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Maize~~]]	+	[[Category: Zea mays]]
-	[[Category: Liu~~, Z C~~]]	+	[[Category: Liu ZC]]
-	[[Category: Wang~~, G G~~]]	+	[[Category: Wang GG]]
-	[[Category: Xie, T]]	+	[[Category: Xie T]]
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 07:52, 11 March 2020

2020-03-11T07:52:57Z

←Older revision		Revision as of 07:52, 11 March 2020
Line 3:		Line 3:
	<StructureSection load='6klj' size='340' side='right'caption='[[6klj]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='6klj' size='340' side='right'caption='[[6klj]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6klj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KLJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6klj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Maize Maize]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KLJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIY:(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENAL'>CIY</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIY:(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENAL'>CIY</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6klg\|6klg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6klg\|6klg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lac3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 MAIZE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klj OCA], [http://pdbe.org/6klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6klj RCSB], [http://www.ebi.ac.uk/pdbsum/6klj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6klj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klj OCA], [http://pdbe.org/6klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6klj RCSB], [http://www.ebi.ac.uk/pdbsum/6klj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6klj ProSAT]</span></td></tr>
Line 11:		Line 12:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/Q2PAJ1_MAIZE Q2PAJ1_MAIZE]] Lignin degradation and detoxification of lignin-derived products.[RuleBase:RU361119]		[[http://www.uniprot.org/uniprot/Q2PAJ1_MAIZE Q2PAJ1_MAIZE]] Lignin degradation and detoxification of lignin-derived products.[RuleBase:RU361119]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Plant laccases catalyse the oxidation of monolignols in lignification, a process reinforcing the cell wall of many different cell types that provide mechanical support, nutrient transportation and defence against pathogens in plants(1). The isozymes display a broad range of substrate preferences. Here, the substrate preference of a laccase (ZmLac3) from Zea mays (maize) was characterized. The crystal structure of ZmLac3 revealed a compact and deep substrate-binding pocket, and the binding modes of sinapyl alcohol (SinA) and coniferyl alcohol (ConA) were solved. On the basis of structural data and kinetics analysis, we propose that the regionalization of polar and hydrophobic surfaces in the binding pocket of ZmLac3 is vital for defining the orientation of SinA/ConA binding. The extra methoxyl group in SinA makes substantial contributions to interactions between SinA and ZmLac3, which are absent in the ZmLac3-ConA complex. In summary, the polar and hydrophobic interactions between SinA/ConA and ZmLac3 determine the binding positions of the monolignols in ZmLac3. These results provide valuable insight about ZmLac3 catalysis and should aid industrial processes that use plant laccases.
		+
		+	Structural basis for monolignol oxidation by a maize laccase.,Xie T, Liu Z, Wang G Nat Plants. 2020 Mar 2. pii: 10.1038/s41477-020-0595-5. doi:, 10.1038/s41477-020-0595-5. PMID:32123349<ref>PMID:32123349</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6klj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Laccase]]		[[Category: Laccase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Maize]]
	[[Category: Liu, Z C]]		[[Category: Liu, Z C]]
	[[Category: Wang, G G]]		[[Category: Wang, G G]]
	[[Category: Xie, T]]		[[Category: Xie, T]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 08:18, 1 January 2020

2020-01-01T08:18:27Z

←Older revision		Revision as of 08:18, 1 January 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6klj is ~~ON HOLD until Jul 30 2021~~	+	==Crystal Structure of the Zea Mays laccase 3 complexed with coniferyl==
-		+	<StructureSection load='6klj' size='340' side='right'caption='[[6klj]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors~~: ~~Xie~~, T., ~~Liu~~, Z.C., ~~Wang~~, G.G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6klj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KLJ FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of ~~the Zea Mays laccase 3 complexed with coniferyl~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIY:(2E)-3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENAL'>CIY</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6klg\|6klg]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Laccase Laccase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klj OCA], [http://pdbe.org/6klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6klj RCSB], [http://www.ebi.ac.uk/pdbsum/6klj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6klj ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q2PAJ1_MAIZE Q2PAJ1_MAIZE]] Lignin degradation and detoxification of lignin-derived products.[RuleBase:RU361119]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Laccase]]
		+	[[Category: Large Structures]]
		+	[[Category: Liu, Z C]]
		+	[[Category: Wang, G G]]
	[[Category: Xie, T]]		[[Category: Xie, T]]
-	[[Category: ~~Liu, Z.C]]~~	+	[[Category: Oxidoreductase]]
-	~~[[Category: Wang, G.G~~]]	+

OCA at 13:35, 28 August 2019

2019-08-28T13:35:03Z

←Older revision		Revision as of 13:35, 28 August 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6klj is ON HOLD	+	The entry 6klj is ON HOLD until Jul 30 2021

	Authors: Xie, T., Liu, Z.C., Wang, G.G.		Authors: Xie, T., Liu, Z.C., Wang, G.G.

OCA: Protected "6klj" [edit=sysop:move=sysop]

2019-08-07T04:08:56Z

Protected "6klj" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:08, 7 August 2019

OCA: New page: '''Unreleased structure''' The entry 6klj is ON HOLD Authors: Xie, T., Liu, Z.C., Wang, G.G. Description: Crystal Structure of the Zea Mays laccase 3 complexed with coniferyl [[Categor...

2019-08-07T04:08:54Z

New page: '''Unreleased structure''' The entry 6klj is ON HOLD Authors: Xie, T., Liu, Z.C., Wang, G.G. Description: Crystal Structure of the Zea Mays laccase 3 complexed with coniferyl [[Categor...

New page

'''Unreleased structure'''

The entry 6klj is ON HOLD

Authors: Xie, T., Liu, Z.C., Wang, G.G.

Description: Crystal Structure of the Zea Mays laccase 3 complexed with coniferyl
[[Category: Unreleased Structures]]
[[Category: Xie, T]]
[[Category: Liu, Z.C]]
[[Category: Wang, G.G]]