6l3g - Revision history

OCA at 10:50, 22 November 2023

2023-11-22T10:50:55Z

←Older revision		Revision as of 10:50, 22 November 2023
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	<StructureSection load='6l3g' size='340' side='right'caption='[[6l3g]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='6l3g' size='340' side='right'caption='[[6l3g]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6l3g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_sp.~~_af32~~-~~8bh~~ Bacteroides sp. ~~af32~~-~~8bh~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L3G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6l3g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_sp._AF32-8BH Bacteroides sp. AF32-8BH] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L3G FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.3Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DWZ47_17845 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2302925 Bacteroides sp. AF32-8BH])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l3g OCA], [https://pdbe.org/6l3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l3g RCSB], [https://www.ebi.ac.uk/pdbsum/6l3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l3g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l3g OCA], [https://pdbe.org/6l3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l3g RCSB], [https://www.ebi.ac.uk/pdbsum/6l3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l3g ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A373G551_9BACE A0A373G551_9BACE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacteroides sp. ~~af32~~-~~8bh~~]]	+	[[Category: Bacteroides sp. AF32-8BH]]
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bharath~~, S R~~]]	+	[[Category: Bharath SR]]
-	[[Category: Song, H]]	+	[[Category: Song H]]
-	[[Category: Su, N]]	+	[[Category: Su N]]
-	~~[[Category: Atp dependent dna helicase]]~~	+
-	~~[[Category: Dsdna unwinding]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase-dna complex]]~~	+
-	~~[[Category: Pif1~~]]	+

OCA at 11:45, 23 March 2022

2022-03-23T11:45:07Z

←Older revision		Revision as of 11:45, 23 March 2022
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	<StructureSection load='6l3g' size='340' side='right'caption='[[6l3g]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='6l3g' size='340' side='right'caption='[[6l3g]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6l3g]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L3G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6L3G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6l3g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_sp._af32-8bh Bacteroides sp. af32-8bh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L3G FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6l3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l3g OCA], [~~http~~://pdbe.org/6l3g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6l3g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6l3g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6l3g ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DWZ47_17845 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2302925 Bacteroides sp. AF32-8BH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l3g OCA], [https://pdbe.org/6l3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l3g RCSB], [https://www.ebi.ac.uk/pdbsum/6l3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l3g ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 6l3g" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6l3g" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Helicase 3D structures\|Helicase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacteroides sp. af32-8bh]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bharath, S R]]		[[Category: Bharath, S R]]

OCA at 15:06, 11 December 2019

2019-12-11T15:06:41Z

←Older revision		Revision as of 15:06, 11 December 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6l3g is ~~ON HOLD~~	+	==Structural Basis for DNA Unwinding at Forked dsDNA by two coordinating Pif1 helicases==
		+	<StructureSection load='6l3g' size='340' side='right'caption='[[6l3g]], [[Resolution\|resolution]] 3.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6l3g]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6L3G FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6l3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l3g OCA], [http://pdbe.org/6l3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6l3g RCSB], [http://www.ebi.ac.uk/pdbsum/6l3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6l3g ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pif1 plays multiple roles in maintaining genome stability and preferentially unwinds forked dsDNA, but the mechanism by which Pif1 unwinds forked dsDNA remains elusive. Here we report the structure of Bacteroides sp Pif1 (BaPif1) in complex with a symmetrical double forked dsDNA. Two interacting BaPif1 molecules are bound to each fork of the partially unwound dsDNA, and interact with the 5' arm and 3' ss/dsDNA respectively. Each of the two BaPif1 molecules is an active helicase and their interaction may regulate their helicase activities. The binding of BaPif1 to the 5' arm causes a sharp bend in the 5' ss/dsDNA junction, consequently breaking the first base-pair. BaPif1 bound to the 3' ss/dsDNA junction impacts duplex unwinding by stabilizing the unpaired first base-pair and engaging the second base-pair poised for breaking. Our results provide an unprecedented insight into how two BaPif1 coordinate with each other to unwind the forked dsDNA.

-	~~Authors~~:	+	Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases.,Su N, Byrd AK, Bharath SR, Yang O, Jia Y, Tang X, Ha T, Raney KD, Song H Nat Commun. 2019 Nov 26;10(1):5375. doi: 10.1038/s41467-019-13414-9. PMID:31772234<ref>PMID:31772234</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6l3g" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bharath, S R]]
		+	[[Category: Song, H]]
		+	[[Category: Su, N]]
		+	[[Category: Atp dependent dna helicase]]
		+	[[Category: Dsdna unwinding]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-dna complex]]
		+	[[Category: Pif1]]

OCA: Protected "6l3g" [edit=sysop:move=sysop]

2019-10-16T04:20:33Z

Protected "6l3g" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:20, 16 October 2019

OCA: New page: '''Unreleased structure''' The entry 6l3g is ON HOLD Authors: Description: Category: Unreleased Structures

2019-10-16T04:20:31Z

New page: '''Unreleased structure''' The entry 6l3g is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6l3g is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]