6lim - Revision history

OCA at 11:00, 22 November 2023

2023-11-22T11:00:50Z

←Older revision		Revision as of 11:00, 22 November 2023
Line 1:		Line 1:

	==BRD4-BD1 bound with compound 40==		==BRD4-BD1 bound with compound 40==
-	<StructureSection load='6lim' size='340' side='right'caption='[[6lim]]' scene=''>	+	<StructureSection load='6lim' size='340' side='right'caption='[[6lim]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LIM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6LIM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6lim]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LIM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6lim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lim OCA], [~~http~~://pdbe.org/6lim PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6lim RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6lim PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6lim ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7590951Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EE9:(3~{R})-6-[(4-isoquinolin-4-ylpyrimidin-2-yl)amino]-1,3-dimethyl-4-propan-2-yl-3~{H}-quinoxalin-2-one'>EE9</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lim OCA], [https://pdbe.org/6lim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lim RCSB], [https://www.ebi.ac.uk/pdbsum/6lim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lim ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+
		+	==See Also==
		+	*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cao D]]		[[Category: Cao D]]
	[[Category: Li Y]]		[[Category: Li Y]]
	[[Category: Xiong B]]		[[Category: Xiong B]]

OCA at 12:29, 16 December 2020

2020-12-16T12:29:38Z

←Older revision		Revision as of 12:29, 16 December 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6lim ~~is ON HOLD until Dec 12 2021~~	+	==BRD4-BD1 bound with compound 40==
-		+	<StructureSection load='6lim' size='340' side='right'caption='[[6lim]]' scene=''>
-	~~Authors~~: ~~Xiong~~, B., ~~Cao~~, D., Li, Y.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LIM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LIM FirstGlance]. <br>
-	~~Description: BRD4-BD1 bound with compound 40~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lim OCA], [http://pdbe.org/6lim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lim RCSB], [http://www.ebi.ac.uk/pdbsum/6lim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lim ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Li, Y~~]]	+	__TOC__
-	[[Category: ~~Cao, D~~]]	+	</StructureSection>
-	[[Category: Xiong, B]]	+	[[Category: Large Structures]]
		+	[[Category: Cao D]]
		+	[[Category: Li Y]]
		+	[[Category: Xiong B]]

OCA at 06:33, 1 January 2020

2020-01-01T06:33:23Z

←Older revision		Revision as of 06:33, 1 January 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6lim is ON HOLD	+	The entry 6lim is ON HOLD until Dec 12 2021

	Authors: Xiong, B., Cao, D., Li, Y.		Authors: Xiong, B., Cao, D., Li, Y.
Line 7:		Line 7:
	Description: BRD4-BD1 bound with compound 40		Description: BRD4-BD1 bound with compound 40
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Li, Y]]
	[[Category: Cao, D]]		[[Category: Cao, D]]
	[[Category: Xiong, B]]		[[Category: Xiong, B]]
-	[[Category: Li, Y]]

OCA: Protected "6lim" [edit=sysop:move=sysop]

2019-12-18T05:44:25Z

Protected "6lim" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:44, 18 December 2019

OCA: New page: '''Unreleased structure''' The entry 6lim is ON HOLD Authors: Xiong, B., Cao, D., Li, Y. Description: BRD4-BD1 bound with compound 40 Category: Unreleased Structures [[Category: Ca...

2019-12-18T05:44:24Z

New page: '''Unreleased structure''' The entry 6lim is ON HOLD Authors: Xiong, B., Cao, D., Li, Y. Description: BRD4-BD1 bound with compound 40 Category: Unreleased Structures [[Category: Ca...

New page

'''Unreleased structure'''

The entry 6lim is ON HOLD

Authors: Xiong, B., Cao, D., Li, Y.

Description: BRD4-BD1 bound with compound 40
[[Category: Unreleased Structures]]
[[Category: Cao, D]]
[[Category: Xiong, B]]
[[Category: Li, Y]]