6lvt - Revision history

OCA at 10:54, 14 June 2023

2023-06-14T10:54:21Z

←Older revision		Revision as of 10:54, 14 June 2023
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	<StructureSection load='6lvt' size='340' side='right'caption='[[6lvt]]' scene=''>		<StructureSection load='6lvt' size='340' side='right'caption='[[6lvt]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6LVT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6lvt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LVT FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6lvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvt OCA], [~~http~~://pdbe.org/6lvt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6lvt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6lvt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvt ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvt OCA], [https://pdbe.org/6lvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lvt RCSB], [https://www.ebi.ac.uk/pdbsum/6lvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvt ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACP_THEMA ACP_THEMA] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Thermotoga maritima, a deep-branching hyperthermophilic bacterium, expresses an extraordinarily stable Thermotoga maritima acyl carrier protein (Tm-ACP) that functions as a carrier in the fatty acid synthesis system at near-boiling aqueous environments. Here, to understand the hyperthermal adaptation of Tm-ACP, we investigated the structure and dynamics of Tm-ACP by nuclear magnetic resonance (NMR) spectroscopy. The melting temperature of Tm-ACP (101.4 degrees C) far exceeds that of other ACPs, owing to extensive ionic interactions and tight hydrophobic packing. The D59 residue, which replaces Pro/Ser of other ACPs, mediates ionic clustering between helices III and IV. This creates a wide pocket entrance to facilitate the accommodation of long acyl chains required for hyperthermal adaptation of the T. maritima cell membrane. Tm-ACP is revealed to be the first ACP that harbor an amide proton hyperprotected against hydrogen/deuterium exchange for I15. The hydrophobic interactions mediated by I15 appear to be the key driving forces of the global folding process of Tm-ACP. Our findings provide insights into the structural basis of the hyperthermal adaptation of ACP, which might have allowed T. maritima to survive in hot ancient oceans.
		+
		+	Structural Characterization of an ACP from Thermotoga maritima: Insights into Hyperthermal Adaptation.,Lee Y, Jang A, Jeong MC, Park N, Park J, Lee WC, Cheong C, Kim Y Int J Mol Sci. 2020 Apr 9;21(7). pii: ijms21072600. doi: 10.3390/ijms21072600. PMID:32283632<ref>PMID:32283632</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6lvt" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Thermotoga maritima MSB8]]
	[[Category: Kim Y]]		[[Category: Kim Y]]
	[[Category: Lee Y]]		[[Category: Lee Y]]

OCA at 06:35, 9 December 2020

2020-12-09T06:35:11Z

←Older revision		Revision as of 06:35, 9 December 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6lvt ~~is ON HOLD until Feb 05 2022~~	+	==Solution structure of holo acyl carrier protein from Thermotoga maritima==
-		+	<StructureSection load='6lvt' size='340' side='right'caption='[[6lvt]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LVT FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvt OCA], [http://pdbe.org/6lvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lvt RCSB], [http://www.ebi.ac.uk/pdbsum/6lvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvt ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Kim Y]]
		+	[[Category: Lee Y]]

OCA at 05:08, 19 February 2020

2020-02-19T05:08:15Z

←Older revision		Revision as of 05:08, 19 February 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6lvt is ON HOLD	+	The entry 6lvt is ON HOLD until Feb 05 2022

	Authors:		Authors:

OCA: Protected "6lvt" [edit=sysop:move=sysop]

2020-02-13T02:34:37Z

Protected "6lvt" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:34, 13 February 2020

OCA: New page: '''Unreleased structure''' The entry 6lvt is ON HOLD Authors: Description: Category: Unreleased Structures

2020-02-13T02:34:35Z

New page: '''Unreleased structure''' The entry 6lvt is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6lvt is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]