6msf - Revision history

OCA at 11:07, 2 August 2023

2023-08-02T11:07:09Z

←Older revision		Revision as of 11:07, 2 August 2023
Line 1:		Line 1:

	==F6 APTAMER MS2 COAT PROTEIN COMPLEX==		==F6 APTAMER MS2 COAT PROTEIN COMPLEX==
-	<StructureSection load='6msf' size='340' side='right' caption='[[6msf]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='6msf' size='340' side='right'caption='[[6msf]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bacteriophage_ms2 Bacteriophage ms2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6MSF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MSF FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~COAT PROTEIN (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=12022 Bacteriophage MS2])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [~~http~~://pdbe.org/6msf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6msf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6msf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [https://pdbe.org/6msf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [https://www.ebi.ac.uk/pdbsum/6msf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6msf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~COAT_BPMS2 COAT_BPMS2~~]~~] Forms~~ the ~~phage~~ shell~~; binds~~ to the ~~phage~~ RNA.	+	[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/6msf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/6msf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteriophage ms2~~]]	+	[[Category: Escherichia phage MS2]]
-	[[Category: Convery~~, M A~~]]	+	[[Category: Large Structures]]
-	[[Category: Ellington~~, A D~~]]	+	[[Category: Convery MA]]
-	[[Category: Hirao, I]]	+	[[Category: Ellington AD]]
-	[[Category: Murray~~, J B~~]]	+	[[Category: Hirao I]]
-	[[Category: Peabody~~, D S~~]]	+	[[Category: Murray JB]]
-	[[Category: Phillips~~, S E.V~~]]	+	[[Category: Peabody DS]]
-	[[Category: Rowsell, S]]	+	[[Category: Phillips SEV]]
-	[[Category: Stockley~~, P G~~]]	+	[[Category: Rowsell S]]
-	[[Category: Stonehouse~~, N J]]~~	+	[[Category: Stockley PG]]
-	~~[[Category: Icosahedral virus]]~~	+	[[Category: Stonehouse NJ]]
-	~~[[Category: Rna aptamer]]~~	+
-	~~[[Category: Rna stem loop]]~~	+
-	~~[[Category: Viral coat protein-rna complex]]~~	+
-	~~[[Category: Virus-rna complex~~]]	+

OCA at 21:48, 4 August 2016

2016-08-04T21:48:49Z

←Older revision		Revision as of 21:48, 4 August 2016
Line 1:		Line 1:
		+
	==F6 APTAMER MS2 COAT PROTEIN COMPLEX==		==F6 APTAMER MS2 COAT PROTEIN COMPLEX==
	<StructureSection load='6msf' size='340' side='right' caption='[[6msf]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='6msf' size='340' side='right' caption='[[6msf]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacterio_phage_ms2 Enterobacterio phage~~ ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSF FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 ~~Enterobacterio phage~~ MS2])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Bacteriophage MS2])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://pdbe.org/6msf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6msf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=6msf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 6msf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacterio phage~~ ms2]]	+	[[Category: Bacteriophage ms2]]
	[[Category: Convery, M A]]		[[Category: Convery, M A]]
	[[Category: Ellington, A D]]		[[Category: Ellington, A D]]
Line 40:		Line 42:
	[[Category: Stockley, P G]]		[[Category: Stockley, P G]]
	[[Category: Stonehouse, N J]]		[[Category: Stonehouse, N J]]
-	[[Category: Bacteriophage ms2]]
	[[Category: Icosahedral virus]]		[[Category: Icosahedral virus]]
	[[Category: Rna aptamer]]		[[Category: Rna aptamer]]

OCA at 13:25, 25 December 2014

2014-12-25T13:25:28Z

←Older revision		Revision as of 13:25, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
-	[[Category: Convery, M A.]]	+	[[Category: Convery, M A]]
-	[[Category: Ellington, A D.]]	+	[[Category: Ellington, A D]]
-	[[Category: Hirao, I.]]	+	[[Category: Hirao, I]]
-	[[Category: Murray, J B.]]	+	[[Category: Murray, J B]]
-	[[Category: Peabody, D S.]]	+	[[Category: Peabody, D S]]
-	[[Category: Phillips, S E.V.]]	+	[[Category: Phillips, S E.V]]
-	[[Category: Rowsell, S.]]	+	[[Category: Rowsell, S]]
-	[[Category: Stockley, P G.]]	+	[[Category: Stockley, P G]]
-	[[Category: Stonehouse, N J.]]	+	[[Category: Stonehouse, N J]]
	[[Category: Bacteriophage ms2]]		[[Category: Bacteriophage ms2]]
	[[Category: Icosahedral virus]]		[[Category: Icosahedral virus]]

OCA: Protected "6msf" [edit=sysop:move=sysop]

2014-06-05T07:45:34Z

Protected "6msf" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:45, 5 June 2014

OCA at 07:45, 5 June 2014

2014-06-05T07:45:31Z

←Older revision		Revision as of 07:45, 5 June 2014
Line 1:		Line 1:
-	~~{{Seed}}~~	+	==F6 APTAMER MS2 COAT PROTEIN COMPLEX==
-	[[~~Image~~:6msf.~~png\|left~~\|200px]]	+	<StructureSection load='6msf' size='340' side='right' caption='[[6msf]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MSF FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/6msf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure, at 2.8 A resolution, of an RNA aptamer bound to bacteriophage MS2 coat protein has been determined. It provides an opportunity to compare the interactions of MS2 coat protein and wild type operator with those of an aptamer, whose secondary structure differs from the wild type RNA in having a three-base loop (compared to a tetraloop) and an additional base pair between this loop and the sequence-specific recognition element in the stem. The RNA binds in the same location on the coat protein as the wild type operator and maintains many of the same RNA-protein interactions. In order to achieve this, the RNA stem loop undergoes a concerted rearrangement of the 3' side while leaving the 5' side and the loop interactions largely unchanged, illustrating the ability of RNA to present similar molecular recognition surfaces from distinct primary and secondary structures.

-	<!--	+	Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution.,Convery MA, Rowsell S, Stonehouse NJ, Ellington AD, Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley PG Nat Struct Biol. 1998 Feb;5(2):133-9. PMID:9461079<ref>PMID:9461079</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_6msf"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_6msf\| PDB=6msf \| SCENE= }}~~	+

-	~~===F6 APTAMER MS2 COAT PROTEIN COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_9461079}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 9461079 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_9461079}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~6MSF is a 5 chains structure of sequences from [http:~~/~~/en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:9461079<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Convery, M A.]]		[[Category: Convery, M A.]]
Line 38:		Line 42:
	[[Category: Rna aptamer]]		[[Category: Rna aptamer]]
	[[Category: Rna stem loop]]		[[Category: Rna stem loop]]
-	[[Category: Viral coat protein/rna complex]]	+	[[Category: Viral coat protein-rna complex]]
-		+	[[Category: Virus-rna complex]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 17:21:35 2009''~~	+

OCA at 15:21, 17 February 2009

2009-02-17T15:21:35Z

←Older revision		Revision as of 15:21, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	6MSF is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA].	+	6MSF is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA].

	==Reference==		==Reference==
-	Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution., Convery MA, Rowsell S, Stonehouse NJ, Ellington AD, Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley PG, Nat Struct Biol. 1998 Feb;5(2):133-9. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/9461079 9461079]~~	+	<ref group="xtra">PMID:9461079</ref><references group="xtra"/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
-	[[Category: Single protein]]
	[[Category: Convery, M A.]]		[[Category: Convery, M A.]]
	[[Category: Ellington, A D.]]		[[Category: Ellington, A D.]]
Line 41:		Line 40:
	[[Category: Viral coat protein/rna complex]]		[[Category: Viral coat protein/rna complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jul 3 14~~:22:~~16 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:21:35 2009''

OCA at 11:22, 3 July 2008

2008-07-03T11:22:16Z

←Older revision		Revision as of 11:22, 3 July 2008
Line 1:		Line 1:
-	[[Image:6msf.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:6msf.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_6msf\| PDB=6msf \| SCENE= }}		{{STRUCTURE_6msf\| PDB=6msf \| SCENE= }}

-	~~'''~~F6 APTAMER MS2 COAT PROTEIN COMPLEX~~'''~~	+	===F6 APTAMER MS2 COAT PROTEIN COMPLEX===


-	~~==Overview==~~	+	<!--
-	The ~~crystal structure~~, ~~at 2.8 A resolution~~, ~~of an RNA aptamer bound to bacteriophage MS2 coat protein has been determined. It provides an opportunity~~ to ~~compare~~ the ~~interactions of MS2 coat protein and wild type operator with those of an aptamer, whose secondary structure differs from the wild type RNA in having a three-base loop~~ (~~compared to a tetraloop) and an additional base pair between this loop and the sequence-specific recognition element in the stem. The RNA binds in the same location~~ on ~~the coat protein as the wild type operator and maintains many of the same RNA-protein interactions~~. ~~In order to achieve this~~, the RNA stem loop undergoes a concerted rearrangement of the 3' side while leaving the 5' side and the loop interactions largely unchanged, illustrating the ability of RNA to present similar molecular recognition surfaces from distinct primary and secondary structures.	+	The line below this paragraph, {{ABSTRACT_PUBMED_9461079}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 9461079 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_9461079}}

	==About this Structure==		==About this Structure==
Line 36:		Line 40:
	[[Category: Rna stem loop]]		[[Category: Rna stem loop]]
	[[Category: Viral coat protein/rna complex]]		[[Category: Viral coat protein/rna complex]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May~~ ~~4 22~~:41:47 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 14:22:16 2008''

OCA at 19:41, 4 May 2008

2008-05-04T19:41:48Z

←Older revision		Revision as of 19:41, 4 May 2008
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	[[Image:6msf.gif\|left\|200px]]		[[Image:6msf.gif\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 6msf \|SIZE=350\|CAPTION=~~ <~~scene name='initialview01'>6msf</scene>, resolution 2.800Å~~	+	The line below this paragraph, containing "STRUCTURE_6msf", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=A:ADENOSINE~~-~~5'~~-~~MONOPHOSPHATE'>A</scene>~~, ~~<scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>~~, ~~<scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene>~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY=~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE= COAT PROTEIN~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2]~~)	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_6msf\| PDB=6msf \| SCENE= }}
-	~~\|RELATEDENTRY=~~	+
-	\|~~RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol~~=6msf ~~FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id~~=~~6msf OCA], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB]</span>~~	+
-	}}	+

	'''F6 APTAMER MS2 COAT PROTEIN COMPLEX'''		'''F6 APTAMER MS2 COAT PROTEIN COMPLEX'''
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	[[Category: Stockley, P G.]]		[[Category: Stockley, P G.]]
	[[Category: Stonehouse, N J.]]		[[Category: Stonehouse, N J.]]
-	[[Category: ~~bacteriophage~~ ms2]]	+	[[Category: Bacteriophage ms2]]
-	[[Category: ~~icosahedral~~ virus]]	+	[[Category: Icosahedral virus]]
-	[[Category: ~~rna~~ aptamer]]	+	[[Category: Rna aptamer]]
-	[[Category: ~~rna~~ stem loop]]	+	[[Category: Rna stem loop]]
-	[[Category: ~~viral~~ coat protein/rna complex]]	+	[[Category: Viral coat protein/rna complex]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:41:47 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 05~~:43:19 2008''	+

OCA at 02:43, 31 March 2008

2008-03-31T02:43:20Z

←Older revision		Revision as of 02:43, 31 March 2008
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	\|PDB= 6msf \|SIZE=350\|CAPTION= <scene name='initialview01'>6msf</scene>, resolution 2.800Å		\|PDB= 6msf \|SIZE=350\|CAPTION= <scene name='initialview01'>6msf</scene>, resolution 2.800Å
	\|SITE=		\|SITE=
-	\|LIGAND=	+	\|LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene>
	\|ACTIVITY=		\|ACTIVITY=
	\|GENE= COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])		\|GENE= COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])
		+	\|DOMAIN=
		+	\|RELATEDENTRY=
		+	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6msf OCA], [http://www.ebi.ac.uk/pdbsum/6msf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=6msf RCSB]</span>
	}}		}}

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	[[Category: viral coat protein/rna complex]]		[[Category: viral coat protein/rna complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Mar ~~20 19~~:13:47 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:43:19 2008''

OCA at 17:13, 20 March 2008

2008-03-20T17:13:48Z

←Older revision		Revision as of 17:13, 20 March 2008
Line 1:		Line 1:
-	[[Image:6msf.gif\|left\|200px]]~~<br /><applet load~~="6msf~~" size~~="350~~" color~~=~~"white" frame="true" align~~=~~"right" spinBox="true"~~	+	[[Image:6msf.gif\|left\|200px]]
-	~~caption="~~6msf, resolution 2.800Å" />	+
-	'''F6 APTAMER MS2 COAT PROTEIN COMPLEX'''~~<br />~~	+	{{Structure
		+	\|PDB= 6msf \|SIZE=350\|CAPTION= <scene name='initialview01'>6msf</scene>, resolution 2.800Å
		+	\|SITE=
		+	\|LIGAND=
		+	\|ACTIVITY=
		+	\|GENE= COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])
		+	}}
		+
		+	'''F6 APTAMER MS2 COAT PROTEIN COMPLEX'''
		+

	==Overview==		==Overview==
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	==About this Structure==		==About this Structure==
-	6MSF is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA].	+	6MSF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MSF OCA].

	==Reference==		==Reference==
-	Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution., Convery MA, Rowsell S, Stonehouse NJ, Ellington AD, Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley PG, Nat Struct Biol. 1998 Feb;5(2):133-9. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~9461079 9461079]	+	Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution., Convery MA, Rowsell S, Stonehouse NJ, Ellington AD, Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley PG, Nat Struct Biol. 1998 Feb;5(2):133-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9461079 9461079]
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Single protein]]		[[Category: Single protein]]
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	[[Category: viral coat protein/rna complex]]		[[Category: viral coat protein/rna complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21~~ 19:16:32 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:13:47 2008''