6mwf - Revision history

OCA at 06:40, 11 October 2023

2023-10-11T06:40:09Z

←Older revision		Revision as of 06:40, 11 October 2023
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	<StructureSection load='6mwf' size='340' side='right'caption='[[6mwf]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6mwf' size='340' side='right'caption='[[6mwf]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6mwf]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Burp1 Burp1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MWF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6MWF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6mwf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1710b Burkholderia pseudomallei 1710b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MWF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SFY:4-AMINO-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE'>SFY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ispF, BURPS1710b_2511 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=320372 BURP1])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SFY:4-AMINO-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE'>SFY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mwf OCA], [https://pdbe.org/6mwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mwf RCSB], [https://www.ebi.ac.uk/pdbsum/6mwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mwf ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6mwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mwf OCA], [~~http~~://pdbe.org/6mwf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6mwf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6mwf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6mwf ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ISPF_BURP1 ISPF_BURP1]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]	+	[https://www.uniprot.org/uniprot/ISPF_BURP1 ISPF_BURP1] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
		+
		+	==See Also==
		+	*[[MECDP synthase 3D structures\|MECDP synthase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]~~	+	[[Category: Burkholderia pseudomallei 1710b]]
-	~~[[Category: Burp1~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Structural genomic]]
-	[[Category: Lyase]]
-	[[Category: Ssgcid]]

OCA at 17:34, 20 November 2019

2019-11-20T17:34:01Z

←Older revision		Revision as of 17:34, 20 November 2019
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	<StructureSection load='6mwf' size='340' side='right'caption='[[6mwf]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6mwf' size='340' side='right'caption='[[6mwf]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6mwf]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MWF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6mwf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Burp1 Burp1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MWF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SFY:4-AMINO-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE'>SFY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SFY:4-AMINO-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE'>SFY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ispF, BURPS1710b_2511 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=320372 BURP1])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mwf OCA], [http://pdbe.org/6mwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mwf RCSB], [http://www.ebi.ac.uk/pdbsum/6mwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mwf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mwf OCA], [http://pdbe.org/6mwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mwf RCSB], [http://www.ebi.ac.uk/pdbsum/6mwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mwf ProSAT]</span></td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]		[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
		+	[[Category: Burp1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]

OCA at 06:41, 6 November 2019

2019-11-06T06:41:52Z

←Older revision		Revision as of 06:41, 6 November 2019
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-	'''Unreleased structure'''

-	~~The entry 6mwf is ON HOLD until Paper Publication~~	+	==Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0459==
-		+	<StructureSection load='6mwf' size='340' side='right'caption='[[6mwf]], [[Resolution\|resolution]] 1.75Å' scene=''>
-	~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6mwf]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MWF FirstGlance]. <br>
-	~~Description:~~ Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0459	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SFY:4-AMINO-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE'>SFY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
-	[[Category: ~~Seattle~~ Structural ~~Genomics Center For Infectious Disease (~~Ssgcid)]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mwf OCA], [http://pdbe.org/6mwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mwf RCSB], [http://www.ebi.ac.uk/pdbsum/6mwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mwf ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ISPF_BURP1 ISPF_BURP1]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
		+	[[Category: Large Structures]]
		+	[[Category: Structural genomic]]
		+	[[Category: Lyase]]
		+	[[Category: Ssgcid]]

OCA at 19:02, 2 December 2018

2018-12-02T19:02:06Z

←Older revision		Revision as of 19:02, 2 December 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6mwf is ON HOLD	+	The entry 6mwf is ON HOLD until Paper Publication

	Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)		Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

OCA: Protected "6mwf" [edit=sysop:move=sysop]

2018-11-07T10:53:22Z

Protected "6mwf" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:53, 7 November 2018

OCA: New page: '''Unreleased structure''' The entry 6mwf is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal structure of 2C-methyl-D-erythrito...

2018-11-07T10:53:21Z

New page: '''Unreleased structure''' The entry 6mwf is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal structure of 2C-methyl-D-erythrito...

New page

'''Unreleased structure'''

The entry 6mwf is ON HOLD

Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0459
[[Category: Unreleased Structures]]
[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]