6n0k - Revision history

OCA at 06:42, 11 October 2023

2023-10-11T06:42:40Z

←Older revision		Revision as of 06:42, 11 October 2023
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	<StructureSection load='6n0k' size='340' side='right'caption='[[6n0k]], [[Resolution\|resolution]] 1.46Å' scene=''>		<StructureSection load='6n0k' size='340' side='right'caption='[[6n0k]], [[Resolution\|resolution]] 1.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n0k]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6N0K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N0K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8M:(3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8M</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.46Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8M:(3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8M</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quercetin_2,3-dioxygenase Quercetin 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.24 1.13.11.24] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0k OCA], [https://pdbe.org/6n0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n0k RCSB], [https://www.ebi.ac.uk/pdbsum/6n0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0k ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6n0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0k OCA], [~~http~~://pdbe.org/6n0k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6n0k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6n0k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0k ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN]] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>	+	[https://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>
		+
		+	==See Also==
		+	*[[Dioxygenase 3D structures\|Dioxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Quercetin 2,3-dioxygenase]]~~	+	[[Category: Jin X]]
-	[[Category: Jin, X]]	+	[[Category: Lisabeth EM]]
-	[[Category: Lisabeth~~, E M~~]]	+	[[Category: Neubig R]]
-	[[Category: Neubig, R]]	+
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Co-transcription factor]]~~	+
-	~~[[Category: Iron-binding]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 11:32, 1 January 2020

2020-01-01T11:32:55Z

←Older revision		Revision as of 11:32, 1 January 2020
Line 3:		Line 3:
	<StructureSection load='6n0k' size='340' side='right'caption='[[6n0k]], [[Resolution\|resolution]] 1.46Å' scene=''>		<StructureSection load='6n0k' size='340' side='right'caption='[[6n0k]], [[Resolution\|resolution]] 1.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n0k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N0K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N0K FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8M:(3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8M</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8M:(3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8M</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quercetin_2,3-dioxygenase Quercetin 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.24 1.13.11.24] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quercetin_2,3-dioxygenase Quercetin 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.24 1.13.11.24] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0k OCA], [http://pdbe.org/6n0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n0k RCSB], [http://www.ebi.ac.uk/pdbsum/6n0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0k ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0k OCA], [http://pdbe.org/6n0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n0k RCSB], [http://www.ebi.ac.uk/pdbsum/6n0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0k ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Quercetin 2,3-dioxygenase]]		[[Category: Quercetin 2,3-dioxygenase]]

OCA at 05:46, 10 July 2019

2019-07-10T05:46:28Z

←Older revision		Revision as of 05:46, 10 July 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 6n0k is ~~ON HOLD until Paper Publication~~	+	==The complex of CCG-257081 bound to pirin==
-		+	<StructureSection load='6n0k' size='340' side='right'caption='[[6n0k]], [[Resolution\|resolution]] 1.46Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6n0k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N0K FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8M:(3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8M</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quercetin_2,3-dioxygenase Quercetin 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.24 1.13.11.24] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0k OCA], [http://pdbe.org/6n0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n0k RCSB], [http://www.ebi.ac.uk/pdbsum/6n0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0k ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN]] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Quercetin 2,3-dioxygenase]]
		+	[[Category: Jin, X]]
		+	[[Category: Lisabeth, E M]]
		+	[[Category: Neubig, R]]
		+	[[Category: Beta barrel]]
		+	[[Category: Co-transcription factor]]
		+	[[Category: Iron-binding]]
		+	[[Category: Oxidoreductase]]

OCA at 10:31, 16 January 2019

2019-01-16T10:31:59Z

←Older revision		Revision as of 10:31, 16 January 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6n0k is ON HOLD	+	The entry 6n0k is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6n0k" [edit=sysop:move=sysop]

2018-11-14T06:46:30Z

Protected "6n0k" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:46, 14 November 2018

OCA: New page: '''Unreleased structure''' The entry 6n0k is ON HOLD Authors: Description: Category: Unreleased Structures

2018-11-14T06:46:29Z

New page: '''Unreleased structure''' The entry 6n0k is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6n0k is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]