6n4v - Revision history

OCA at 03:08, 11 April 2020

2020-04-11T03:08:50Z

←Older revision		Revision as of 03:08, 11 April 2020
Line 3:		Line 3:
	<SX load='6n4v' size='340' side='right' viewer='molstar' caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>		<SX load='6n4v' size='340' side='right' viewer='molstar' caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppp7 Bppp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6N4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppp7 Bppp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6N4V FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6n4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n4v OCA], [http://pdbe.org/6n4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n4v RCSB], [http://www.ebi.ac.uk/pdbsum/6n4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n4v ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6n4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n4v OCA], [http://pdbe.org/6n4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n4v RCSB], [http://www.ebi.ac.uk/pdbsum/6n4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n4v ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:46, 6 March 2020

2020-03-06T22:46:04Z

←Older revision		Revision as of 22:46, 6 March 2020
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	==CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)==		==CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)==
-	<~~StructureSection~~ load='6n4v' size='340' side='right'caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<SX load='6n4v' size='340' side='right' viewer='molstar' caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppp7 Bppp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N4V FirstGlance]. <br>		<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppp7 Bppp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N4V FirstGlance]. <br>
Line 18:		Line 18:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bppp7]]		[[Category: Bppp7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 13:40, 10 May 2019

2019-05-10T13:40:56Z

←Older revision		Revision as of 13:40, 10 May 2019
Line 3:		Line 3:
	<StructureSection load='6n4v' size='340' side='right'caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='6n4v' size='340' side='right'caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppp7 Bppp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N4V FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n4v OCA], [http://pdbe.org/6n4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n4v RCSB], [http://www.ebi.ac.uk/pdbsum/6n4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n4v ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n4v OCA], [http://pdbe.org/6n4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n4v RCSB], [http://www.ebi.ac.uk/pdbsum/6n4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n4v ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bppp7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Carragher, B]]		[[Category: Carragher, B]]

OCA at 07:08, 3 April 2019

2019-04-03T07:08:33Z

←Older revision		Revision as of 07:08, 3 April 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6n4v is ~~ON HOLD until Paper~~ Publication	+	==CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)==
		+	<StructureSection load='6n4v' size='340' side='right'caption='[[6n4v]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6n4v]] is a 120 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N4V FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n4v OCA], [http://pdbe.org/6n4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n4v RCSB], [http://www.ebi.ac.uk/pdbsum/6n4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n4v ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	As self-assembling polyvalent nanoscale structures that can tolerate substantial genetic and chemical modification, virus-like particles are useful in a variety of fields. Here we describe the genetic modification and structural characterization of the Leviviridae PP7 capsid protein as a platform for the presentation of functional polypeptides. This particle was shown to tolerate the display of sequences from 1 kDa (a cell penetrating peptide) to 14 kDa (the Fc-binding double Z-domain) on its exterior surface as C-terminal genetic fusions to the coat protein. In addition, a dimeric construct allowed the presentation of exogenous loops between capsid monomers and the simultaneous presentation of two different peptides at different positions on the icosahedral structure. The PP7 particle is thereby significantly more tolerant of these types of polypeptide additions than Qbeta and MS2, the other Leviviridae-derived VLPs in common use.

-	~~Authors: Liangjun~~, Z., Kopylov, M., Potter~~, C.S.~~, Carragher, B., Finn~~, M~~.G.	+	Engineering the PP7 Virus Capsid as a Peptide Display Platform.,Zhao L, Kopylov M, Potter CS, Carragher B, Finn MG ACS Nano. 2019 Mar 26. doi: 10.1021/acsnano.8b09683. PMID:30912918<ref>PMID:30912918</ref>

-	~~Description: CryoEM structure~~ of ~~Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	[[Category: ~~Potter, C.S~~]]	+	<div class="pdbe-citations 6n4v" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Carragher, B]]		[[Category: Carragher, B]]
		+	[[Category: Finn, M G]]
	[[Category: Kopylov, M]]		[[Category: Kopylov, M]]
	[[Category: Liangjun, Z]]		[[Category: Liangjun, Z]]
-	[[Category: ~~Finn~~, ~~M.G~~]]	+	[[Category: Potter, C S]]
		+	[[Category: Biotechnology]]
		+	[[Category: Drug delivery]]
		+	[[Category: Icosahedral]]
		+	[[Category: Pp7]]
		+	[[Category: T4]]
		+	[[Category: Vaccine]]
		+	[[Category: Virus like particle]]

OCA at 10:33, 16 January 2019

2019-01-16T10:33:05Z

←Older revision		Revision as of 10:33, 16 January 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6n4v is ON HOLD	+	The entry 6n4v is ON HOLD until Paper Publication

	Authors: Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G.		Authors: Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G.
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	Description: CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)		Description: CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Potter, C.S]]
	[[Category: Carragher, B]]		[[Category: Carragher, B]]
	[[Category: Kopylov, M]]		[[Category: Kopylov, M]]
	[[Category: Liangjun, Z]]		[[Category: Liangjun, Z]]
	[[Category: Finn, M.G]]		[[Category: Finn, M.G]]
-	[[Category: Potter, C.S]]

OCA: Protected "6n4v" [edit=sysop:move=sysop]

2018-12-02T19:16:37Z

Protected "6n4v" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:16, 2 December 2018

OCA: New page: '''Unreleased structure''' The entry 6n4v is ON HOLD Authors: Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G. Description: CryoEM structure of Leviviridae PP7 WT coa...

2018-12-02T19:16:36Z

New page: '''Unreleased structure''' The entry 6n4v is ON HOLD Authors: Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G. Description: CryoEM structure of Leviviridae PP7 WT coa...

New page

'''Unreleased structure'''

The entry 6n4v is ON HOLD

Authors: Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G.

Description: CryoEM structure of Leviviridae PP7 WT coat protein dimer capsid (PP7PP7-WT)
[[Category: Unreleased Structures]]
[[Category: Carragher, B]]
[[Category: Kopylov, M]]
[[Category: Liangjun, Z]]
[[Category: Finn, M.G]]
[[Category: Potter, C.S]]