6ne8 - Revision history

OCA at 10:55, 14 June 2023

2023-06-14T10:55:29Z

←Older revision		Revision as of 10:55, 14 June 2023
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	==Solution Structure of the Thioredoxin-like Domain of Arabidopsis NCP (NUCLEAR CONTROL OF PEP ACTIVITY)==		==Solution Structure of the Thioredoxin-like Domain of Arabidopsis NCP (NUCLEAR CONTROL OF PEP ACTIVITY)==
-	<StructureSection load='6ne8' size='340' side='right'caption='[[6ne8~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='6ne8' size='340' side='right'caption='[[6ne8]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ne8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NE8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NE8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ne8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NE8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ne8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ne8 OCA], [~~http~~://pdbe.org/6ne8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ne8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ne8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ne8 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ne8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ne8 OCA], [https://pdbe.org/6ne8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ne8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ne8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ne8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MRL7L_ARATH MRL7L_ARATH]] Plays an essential role in early steps of chloroplast development (PubMed:21515910, PubMed:24111559). Involved in the regulation of plastid gene expression (PubMed:21515910, PubMed:24111559). Required for the proper function of the plastid transcriptional machinery and protein accumulation in thylakoid membranes. May function as molecular chaperone to ensure proper organization of the nucleoids in chloroplasts (PubMed:24111559).<ref>PMID:21515910</ref> <ref>PMID:24111559</ref>	+	[https://www.uniprot.org/uniprot/MRL7L_ARATH MRL7L_ARATH] Plays an essential role in early steps of chloroplast development (PubMed:21515910, PubMed:24111559). Involved in the regulation of plastid gene expression (PubMed:21515910, PubMed:24111559). Required for the proper function of the plastid transcriptional machinery and protein accumulation in thylakoid membranes. May function as molecular chaperone to ensure proper organization of the nucleoids in chloroplasts (PubMed:24111559).<ref>PMID:21515910</ref> <ref>PMID:24111559</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, M]]	+	[[Category: Chen M]]
-	[[Category: Liu, J]]	+	[[Category: Liu J]]
-	[[Category: Zhou, P]]	+	[[Category: Zhou P]]
-	~~[[Category: Chloroplast biogenesis]]~~	+
-	~~[[Category: Ncp]]~~	+
-	~~[[Category: Nuclear control of pep activity]]~~	+
-	~~[[Category: Phytochrome signaling]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Plastid-encoded rna polymerase]]~~	+
-	~~[[Category: Thioredoxin-like domain~~]]	+

OCA at 09:07, 25 December 2019

2019-12-25T09:07:13Z

←Older revision		Revision as of 09:07, 25 December 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6ne8 is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Solution Structure of the Thioredoxin-like Domain of Arabidopsis NCP (NUCLEAR CONTROL OF PEP ACTIVITY)==
		+	<StructureSection load='6ne8' size='340' side='right'caption='[[6ne8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6ne8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NE8 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ne8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ne8 OCA], [http://pdbe.org/6ne8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ne8 RCSB], [http://www.ebi.ac.uk/pdbsum/6ne8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ne8 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MRL7L_ARATH MRL7L_ARATH]] Plays an essential role in early steps of chloroplast development (PubMed:21515910, PubMed:24111559). Involved in the regulation of plastid gene expression (PubMed:21515910, PubMed:24111559). Required for the proper function of the plastid transcriptional machinery and protein accumulation in thylakoid membranes. May function as molecular chaperone to ensure proper organization of the nucleoids in chloroplasts (PubMed:24111559).<ref>PMID:21515910</ref> <ref>PMID:24111559</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs). PhAPGs are transcribed by a bacterial-type RNA polymerase (PEP), but how phytochromes in the nucleus activate chloroplast gene expression remains enigmatic. We report here a forward genetic screen in Arabidopsis that identified NUCLEAR CONTROL OF PEP ACTIVITY (NCP) as a necessary component of phytochrome signaling for PhAPG activation. NCP is dual-targeted to plastids and the nucleus. While nuclear NCP mediates the degradation of two repressors of chloroplast biogenesis, PIF1 and PIF3, NCP in plastids promotes the assembly of the PEP complex for PhAPG transcription. NCP and its paralog RCB are non-catalytic thioredoxin-like proteins that diverged in seed plants to adopt nonredundant functions in phytochrome signaling. These results support a model in which phytochromes control PhAPG expression through light-dependent double nuclear and plastidial switches that are linked by evolutionarily conserved and dual-localized regulatory proteins.

-	~~Authors~~:	+	NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.,Yang EJ, Yoo CY, Liu J, Wang H, Cao J, Li FW, Pryer KM, Sun TP, Weigel D, Zhou P, Chen M Nat Commun. 2019 Jun 14;10(1):2630. doi: 10.1038/s41467-019-10517-1. PMID:31201314<ref>PMID:31201314</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6ne8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Chen, M]]
		+	[[Category: Liu, J]]
		+	[[Category: Zhou, P]]
		+	[[Category: Chloroplast biogenesis]]
		+	[[Category: Ncp]]
		+	[[Category: Nuclear control of pep activity]]
		+	[[Category: Phytochrome signaling]]
		+	[[Category: Plant protein]]
		+	[[Category: Plastid-encoded rna polymerase]]
		+	[[Category: Thioredoxin-like domain]]

OCA at 05:03, 21 February 2019

2019-02-21T05:03:25Z

←Older revision		Revision as of 05:03, 21 February 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ne8 is ON HOLD	+	The entry 6ne8 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6ne8" [edit=sysop:move=sysop]

2018-12-26T06:48:10Z

Protected "6ne8" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:48, 26 December 2018

OCA: New page: '''Unreleased structure''' The entry 6ne8 is ON HOLD Authors: Description: Category: Unreleased Structures

2018-12-26T06:48:08Z

New page: '''Unreleased structure''' The entry 6ne8 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ne8 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]