6nv6 - Revision history

OCA at 07:00, 11 October 2023

2023-10-11T07:00:14Z

←Older revision		Revision as of 07:00, 11 October 2023
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	<StructureSection load='6nv6' size='340' side='right'caption='[[6nv6]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='6nv6' size='340' side='right'caption='[[6nv6]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nv6]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Xanac Xanac~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6NV6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nv6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri_pv._citri_str._306 Xanthomonas citri pv. citri str. 306]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NV6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[4kh7\|4kh7]], [[2c3q\|2c3q]], [[4mpg\|4mpg~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>gst, XAC3819 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~190486 XANAC])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv6 OCA], [https://pdbe.org/6nv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nv6 RCSB], [https://www.ebi.ac.uk/pdbsum/6nv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv6 ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6nv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv6 OCA], [~~http~~://pdbe.org/6nv6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nv6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nv6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv6 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8PG02_XANAC Q8PG02_XANAC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glutathione transferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Xanac]]~~	+	[[Category: Xanthomonas citri pv. citri str. 306]]
-	~~[[Category: Fan, L]]~~	+	[[Category: De Keyser S]]
-	~~[[Category: Hilario, E~~]]	+	[[Category: Fan L]]
-	[[Category: Keyser, S De]]	+	[[Category: Hilario E]]
-	[[Category: ~~Citrus canker~~]]	+
-	[[Category: ~~Dehalogenase]]~~	+
-	~~[[Category: Glutathione s-transferase]]~~	+
-	~~[[Category: Plant pathogen]]~~	+
-	~~[[Category: Theta class gst]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 09:57, 12 August 2020

2020-08-12T09:57:12Z

←Older revision		Revision as of 09:57, 12 August 2020
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	<StructureSection load='6nv6' size='340' side='right'caption='[[6nv6]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='6nv6' size='340' side='right'caption='[[6nv6]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nv6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV6 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NV6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nv6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Xanac Xanac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NV6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kh7\|4kh7]], [[2c3q\|2c3q]], [[4mpg\|4mpg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kh7\|4kh7]], [[2c3q\|2c3q]], [[4mpg\|4mpg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gst, XAC3819 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=190486 XANAC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6nv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv6 OCA], [http://pdbe.org/6nv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nv6 RCSB], [http://www.ebi.ac.uk/pdbsum/6nv6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6nv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv6 OCA], [http://pdbe.org/6nv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nv6 RCSB], [http://www.ebi.ac.uk/pdbsum/6nv6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv6 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The genus Xanthomonas comprises several cosmopolitan plant-pathogenic bacteria that affect more than 400 plant species, most of which are of economic interest. Citrus canker is a bacterial disease that affects citrus species, reducing fruit yield and quality, and is caused by the bacterium Xanthomonas citri subsp. citri (Xac). The Xac3819 gene, which has previously been reported to be important for citrus canker infection, encodes an uncharacterized glutathione S-transferase (GST) of 207 amino-acid residues in length (XacGST). Bacterial GSTs are implicated in a variety of metabolic processes such as protection against chemical and oxidative stresses. XacGST shares high sequence identity (45%) with the GstB dehalogenase from Escherichia coli O6:H1 strain CFT073 (EcGstB). Here, XacGST is reported to be able to conjugate glutathione (GSH) with bromoacetate with a Km of 6.67 +/- 0.77 mM, a kcat of 42.69 +/- 0.32 s(-1) and a kcat/Km of 6.40 +/- 0.72 mM(-1) s(-1) under a saturated GSH concentration (3.6 mM). These values are comparable to those previously reported for EcGstB. In addition, crystal structures of XacGST were determined in the apo form (PDB entry 6nxv) and in a GSH-bound complex (PDB entry 6nv6). XacGST has a canonical GST-like fold with a conserved serine residue (Ser12) at the GSH-binding site near the N-terminus, indicating XacGST to be a serine-type GST that probably belongs to the theta-class GSTs. GSH binding stabilizes a loop of about 20 residues containing a helix that is disordered in the apo XacGST structure.
		+
		+	Structural and biochemical characterization of a glutathione transferase from the citrus canker pathogen Xanthomonas.,Hilario E, De Keyser S, Fan L Acta Crystallogr D Struct Biol. 2020 Aug 1;76(Pt 8):778-789. doi:, 10.1107/S2059798320009274. Epub 2020 Jul 27. PMID:32744260<ref>PMID:32744260</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6nv6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutathione S-transferase 3D structures\|Glutathione S-transferase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Xanac]]
	[[Category: Fan, L]]		[[Category: Fan, L]]
	[[Category: Hilario, E]]		[[Category: Hilario, E]]

OCA at 06:43, 4 March 2020

2020-03-04T06:43:12Z

←Older revision		Revision as of 06:43, 4 March 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6nv6 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the theta class glutathione S-transferase from the citrus canker pathogen Xanthomonas axonopodis pv. citri with glutathione bound==
-		+	<StructureSection load='6nv6' size='340' side='right'caption='[[6nv6]], [[Resolution\|resolution]] 2.65Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6nv6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NV6 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4kh7\|4kh7]], [[2c3q\|2c3q]], [[4mpg\|4mpg]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv6 OCA], [http://pdbe.org/6nv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nv6 RCSB], [http://www.ebi.ac.uk/pdbsum/6nv6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv6 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Glutathione transferase]]
		+	[[Category: Large Structures]]
		+	[[Category: Fan, L]]
		+	[[Category: Hilario, E]]
		+	[[Category: Keyser, S De]]
		+	[[Category: Citrus canker]]
		+	[[Category: Dehalogenase]]
		+	[[Category: Glutathione s-transferase]]
		+	[[Category: Plant pathogen]]
		+	[[Category: Theta class gst]]
		+	[[Category: Transferase]]

OCA at 05:37, 6 March 2019

2019-03-06T05:37:05Z

←Older revision		Revision as of 05:37, 6 March 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nv6 is ON HOLD	+	The entry 6nv6 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6nv6" [edit=sysop:move=sysop]

2019-02-13T07:48:45Z

Protected "6nv6" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:48, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6nv6 is ON HOLD Authors: Description: Category: Unreleased Structures

2019-02-13T07:48:44Z

New page: '''Unreleased structure''' The entry 6nv6 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6nv6 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]