6nx0 - Revision history

OCA at 07:01, 11 October 2023

2023-10-11T07:01:13Z

←Older revision		Revision as of 07:01, 11 October 2023
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	<StructureSection load='6nx0' size='340' side='right'caption='[[6nx0]], [[Resolution\|resolution]] 1.54Å' scene=''>		<StructureSection load='6nx0' size='340' side='right'caption='[[6nx0]], [[Resolution\|resolution]] 1.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nx0]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Burta Burta~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NX0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nx0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_thailandensis_E264 Burkholderia thailandensis E264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NX0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.54Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BTH_II1092 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nx0 OCA], [~~http~~://pdbe.org/6nx0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nx0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nx0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nx0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nx0 OCA], [https://pdbe.org/6nx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nx0 RCSB], [https://www.ebi.ac.uk/pdbsum/6nx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nx0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q2T6B0_BURTA Q2T6B0_BURTA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burta~~]]	+	[[Category: Burkholderia thailandensis E264]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cohen~~, S E~~]]	+	[[Category: Cohen SE]]
-	[[Category: Drennan~~, C L]]~~	+	[[Category: Drennan CL]]
-	~~[[Category: Diheme]]~~	+
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Peroxidase~~]]	+

OCA at 11:43, 1 January 2020

2020-01-01T11:43:40Z

←Older revision		Revision as of 11:43, 1 January 2020
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	<StructureSection load='6nx0' size='340' side='right'caption='[[6nx0]], [[Resolution\|resolution]] 1.54Å' scene=''>		<StructureSection load='6nx0' size='340' side='right'caption='[[6nx0]], [[Resolution\|resolution]] 1.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nx0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nx0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burta Burta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NX0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BTH_II1092 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nx0 OCA], [http://pdbe.org/6nx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nx0 RCSB], [http://www.ebi.ac.uk/pdbsum/6nx0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nx0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nx0 OCA], [http://pdbe.org/6nx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nx0 RCSB], [http://www.ebi.ac.uk/pdbsum/6nx0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nx0 ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 6nx0" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6nx0" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome c peroxidase 3D structures\|Cytochrome c peroxidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Burta]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cohen, S E]]		[[Category: Cohen, S E]]

OCA at 08:04, 20 March 2019

2019-03-20T08:04:58Z

←Older revision		Revision as of 08:04, 20 March 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6nx0 is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of the diheme peroxidase BthA from Burkholderia thailandensis E264==
		+	<StructureSection load='6nx0' size='340' side='right'caption='[[6nx0]], [[Resolution\|resolution]] 1.54Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6nx0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NX0 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nx0 OCA], [http://pdbe.org/6nx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nx0 RCSB], [http://www.ebi.ac.uk/pdbsum/6nx0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nx0 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial diheme peroxidases represent a diverse enzyme family with functions that range from hydrogen peroxide (H2O2) reduction to post-translational modifications. By implementing a sequence similarity network (SSN) of the bCCP_MauG superfamily, we present the discovery of a unique diheme peroxidase BthA conserved in all Burkholderia. Using a combination of magnetic resonance, near-IR and Mossbauer spectroscopies and electrochemical methods, we report that BthA is capable of generating a bis-Fe(IV) species previously thought to be a unique feature of the diheme enzyme MauG. However, BthA is not MauG-like in that it catalytically converts H2O2 to water, and a 1.54-A resolution crystal structure reveals striking differences between BthA and other superfamily members, including the essential residues for both bis-Fe(IV) formation and H2O2 turnover. Taken together, we find that BthA represents a previously undiscovered class of diheme enzymes, one that stabilizes a bis-Fe(IV) state and catalyzes H2O2 turnover in a mechanistically distinct manner.

-	~~Authors~~:	+	A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state.,Rizzolo K, Cohen SE, Weitz AC, Lopez Munoz MM, Hendrich MP, Drennan CL, Elliott SJ Nat Commun. 2019 Mar 7;10(1):1101. doi: 10.1038/s41467-019-09020-4. PMID:30846684<ref>PMID:30846684</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6nx0" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Cohen, S E]]
		+	[[Category: Drennan, C L]]
		+	[[Category: Diheme]]
		+	[[Category: Heme]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Peroxidase]]

OCA at 05:10, 21 February 2019

2019-02-21T05:10:28Z

←Older revision		Revision as of 05:10, 21 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nx0 is ON HOLD	+	The entry 6nx0 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6nx0" [edit=sysop:move=sysop]

2019-02-13T07:54:31Z

Protected "6nx0" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:54, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6nx0 is ON HOLD Authors: Description: Category: Unreleased Structures

2019-02-13T07:54:30Z

New page: '''Unreleased structure''' The entry 6nx0 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6nx0 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]