6qsr - Revision history

OCA at 12:07, 24 January 2024

2024-01-24T12:07:51Z

←Older revision		Revision as of 12:07, 24 January 2024
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	<StructureSection load='6qsr' size='340' side='right'caption='[[6qsr]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='6qsr' size='340' side='right'caption='[[6qsr]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qsr]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cip_109074 Cip 109074~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QSR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qsr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenorhabdus_doucetiae Xenorhabdus doucetiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QSR FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[3esi\|3esi~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~XDD1_3466 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=351671 CIP 109074]), XDD1_3473 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=351671 CIP 109074])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsr OCA], [https://pdbe.org/6qsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qsr RCSB], [https://www.ebi.ac.uk/pdbsum/6qsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsr ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsr OCA], [~~http~~://pdbe.org/6qsr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qsr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qsr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsr ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A068QWX2_9GAMM A0A068QWX2_9GAMM]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cip 109074]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bode, H~~]]	+	[[Category: Xenorhabdus doucetiae]]
-	[[Category: ~~Grammbitter, G L.C~~]]	+	[[Category: Bode H]]
-	[[Category: ~~Groll, M~~]]	+	[[Category: Grammbitter GLC]]
-	[[Category: ~~Schmalhofer,~~ M]]	+	[[Category: Groll M]]
-	[[Category: ~~Aryl polyene pigment]]~~	+	[[Category: Schmalhofer M]]
-	~~[[Category: Biosynthesis]]~~	+
-	~~[[Category: Biosynthetic protein]]~~	+
-	~~[[Category: Dehydration]]~~	+
-	~~[[Category: Type ii polyketide synthase~~]]	+

OCA at 09:40, 30 October 2019

2019-10-30T09:40:12Z

←Older revision		Revision as of 09:40, 30 October 2019
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	<StructureSection load='6qsr' size='340' side='right'caption='[[6qsr]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='6qsr' size='340' side='right'caption='[[6qsr]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qsr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QSR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qsr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cip_109074 Cip 109074]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QSR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3esi\|3esi]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3esi\|3esi]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XDD1_3466 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=351671 CIP 109074]), XDD1_3473 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=351671 CIP 109074])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsr OCA], [http://pdbe.org/6qsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qsr RCSB], [http://www.ebi.ac.uk/pdbsum/6qsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsr OCA], [http://pdbe.org/6qsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qsr RCSB], [http://www.ebi.ac.uk/pdbsum/6qsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsr ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 6qsr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6qsr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures\|Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cip 109074]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bode, H]]		[[Category: Bode, H]]

OCA at 07:14, 3 April 2019

2019-04-03T07:14:52Z

←Older revision		Revision as of 07:14, 3 April 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 6qsr is ~~ON HOLD until Paper~~ Publication	+	==The Dehydratase Heterocomplex ApeI:P from Xenorhabdus doucetiae==
		+	<StructureSection load='6qsr' size='340' side='right'caption='[[6qsr]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6qsr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QSR FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3esi\|3esi]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsr OCA], [http://pdbe.org/6qsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qsr RCSB], [http://www.ebi.ac.uk/pdbsum/6qsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsr ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aryl polyene (APE) pigments are a widely distributed class of bacterial polyketides. So far, little is known about the biosynthesis of these compounds, which are produced by a novel type II polyketide synthase (PKS). We have identi-fied all enzymes involved in APE biosynthesis and determined their peculiar functions. The biosynthesis was recon-stituted in vitro and ACP-bound intermediates were assigned for each reaction step by HPLC-MS. Native mass spec-trometry experiments identified four stable complexes: the acyl-carrier proteins ApeE and ApeF bound to the thi-oesterase ApeK, the dehydratases ApeI and ApeP as well as the ketosynthase ApeO in complex with its chain-length factor ApeC. X-ray structures of the heterodimeric ApeO:ApeC and ApeI:ApeP complexes depict striking protein-protein interactions. Altogether, our study elucidated mechanistic aspects of APE biosynthesis that unifies elements of type II fatty acid and PKS systems, but in addition includes novel enzyme complexes.

-	~~Authors: Grammbitter, G.L.C~~., ~~Schmalhofer~~, M., ~~Groll~~, M., Bode~~, H~~.	+	An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments.,Grammbitter GLC, Schmalhofer M, Karimi K, Schoner TA, Tobias NJ, Morgner N, Groll M, Bode HB J Am Chem Soc. 2019 Mar 25. doi: 10.1021/jacs.8b10776. PMID:30908039<ref>PMID:30908039</ref>

-	~~Description~~: ~~The Dehydratase Heterocomplex ApeI:P from Xenorhabdus doucetiae~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6qsr" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bode, H]]
		+	[[Category: Grammbitter, G L.C]]
	[[Category: Groll, M]]		[[Category: Groll, M]]
	[[Category: Schmalhofer, M]]		[[Category: Schmalhofer, M]]
-	[[Category: ~~Bode, H~~]]	+	[[Category: Aryl polyene pigment]]
-	[[Category: ~~Grammbitter, G.L.C~~]]	+	[[Category: Biosynthesis]]
		+	[[Category: Biosynthetic protein]]
		+	[[Category: Dehydration]]
		+	[[Category: Type ii polyketide synthase]]

OCA at 05:49, 6 March 2019

2019-03-06T05:49:48Z

←Older revision		Revision as of 05:49, 6 March 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6qsr is ON HOLD	+	The entry 6qsr is ON HOLD until Paper Publication

	Authors: Grammbitter, G.L.C., Schmalhofer, M., Groll, M., Bode, H.		Authors: Grammbitter, G.L.C., Schmalhofer, M., Groll, M., Bode, H.
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	Description: The Dehydratase Heterocomplex ApeI:P from Xenorhabdus doucetiae		Description: The Dehydratase Heterocomplex ApeI:P from Xenorhabdus doucetiae
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Bode, H]]
	[[Category: Groll, M]]		[[Category: Groll, M]]
	[[Category: Schmalhofer, M]]		[[Category: Schmalhofer, M]]
		+	[[Category: Bode, H]]
	[[Category: Grammbitter, G.L.C]]		[[Category: Grammbitter, G.L.C]]

OCA: Protected "6qsr" [edit=sysop:move=sysop]

2019-02-27T14:02:43Z

Protected "6qsr" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:02, 27 February 2019

OCA: New page: '''Unreleased structure''' The entry 6qsr is ON HOLD Authors: Grammbitter, G.L.C., Schmalhofer, M., Groll, M., Bode, H. Description: The Dehydratase Heterocomplex ApeI:P from Xenorhabd...

2019-02-27T14:02:41Z

New page: '''Unreleased structure''' The entry 6qsr is ON HOLD Authors: Grammbitter, G.L.C., Schmalhofer, M., Groll, M., Bode, H. Description: The Dehydratase Heterocomplex ApeI:P from Xenorhabd...

New page

'''Unreleased structure'''

The entry 6qsr is ON HOLD

Authors: Grammbitter, G.L.C., Schmalhofer, M., Groll, M., Bode, H.

Description: The Dehydratase Heterocomplex ApeI:P from Xenorhabdus doucetiae
[[Category: Unreleased Structures]]
[[Category: Bode, H]]
[[Category: Groll, M]]
[[Category: Schmalhofer, M]]
[[Category: Grammbitter, G.L.C]]