6r0l - Revision history

OCA at 12:12, 24 January 2024

2024-01-24T12:12:30Z

←Older revision		Revision as of 12:12, 24 January 2024
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-	====	+	==Histone fold domain of OsGhd8/NF-YC7 in I2==
-	<StructureSection load='6r0l' size='340' side='right'caption='[[6r0l]]' scene=''>	+	<StructureSection load='6r0l' size='340' side='right'caption='[[6r0l]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6r0l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R0L FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r0l OCA], [https://pdbe.org/6r0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r0l RCSB], [https://www.ebi.ac.uk/pdbsum/6r0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r0l ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r0l OCA], [https://pdbe.org/6r0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r0l RCSB], [https://www.ebi.ac.uk/pdbsum/6r0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r0l ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HD5_ORYSJ HD5_ORYSJ] Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions. Functions as repressor of flowering, independently of HD1 and GHD7. Controls flowering time by negatively regulating the expression of EHD1 and HD3A (PubMed:20566706, PubMed:21148627). Regulates plant height by promoting cell elongation in the internodes (PubMed:20566706). Component of the NF-Y/HAP transcription factor complex (By similarity).<ref>PMID:20566706</ref> <ref>PMID:21148627</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	NF-Y transcription factor comprises three subunits: NF-YA, NF-YB and NF-YC. NF-YB and NF-YC dimerize through their histone fold domain (HFD), which can bind DNA in a non-sequence-specific fashion while serving as a scaffold for NF-YA trimerization. Upon trimerization, NF-YA specifically recognizes the CCAAT box sequence on promoters and enhancers. In plants, each NF-Y subunit is encoded by several genes giving rise to hundreds of potential heterotrimeric combinations. In addition, plant NF-YBs and NF-YCs interact with other protein partners to recognize a plethora of genomic motifs, as the CCT protein family that binds CORE sites. The NF-Y subunit organization and its DNA-binding properties, together with the NF-Y HFD capacity to adapt different protein modules, represent plant-specific features that play a key role in development, growth and reproduction. Despite their relevance, these features are still poorly understood at the molecular level. Here, we present the structures of Arabidopsis and rice NF-YB/NF-YC dimers, and of an Arabidopsis NF-Y trimer in complex with the FT CCAAT box, together with biochemical data on NF-Y mutants. The dimeric structures identify the key residues for NF-Y HFD stabilization. The NF-Y/DNA structure and the mutation experiments shed light on HFD trimerization interface properties and the NF-YA sequence appetite for the bases flanking the CCAAT motif. These data explain the logic of plant NF-Y gene expansion: the trimerization adaptability and the flexible DNA-binding rules serve the scopes of accommodating the large number of NF-YAs, CCTs and possibly other NF-Y HFD binding partners and a diverse audience of genomic motifs.
		+
		+	Structural determinants for NF-Y subunit organization and NF-Y/DNA association in plants.,Chaves-Sanjuan A, Gnesutta N, Gobbini A, Martignago D, Bernardini A, Fornara F, Mantovani R, Nardini M Plant J. 2021 Jan;105(1):49-61. doi: 10.1111/tpj.15038. Epub 2020 Nov 27. PMID:33098724<ref>PMID:33098724</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6r0l" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Nuclear transcription factor Y\|Nuclear transcription factor Y]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z-~~disk~~]]	+	[[Category: Oryza sativa]]
		+	[[Category: Chaves-Sanjuan A]]
		+	[[Category: Gobbini A]]
		+	[[Category: Nardini M]]

OCA at 14:54, 3 March 2021

2021-03-03T14:54:45Z

←Older revision		Revision as of 14:54, 3 March 2021
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	<StructureSection load='6r0l' size='340' side='right'caption='[[6r0l]]' scene=''>		<StructureSection load='6r0l' size='340' side='right'caption='[[6r0l]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6r0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r0l OCA], [~~http~~://pdbe.org/6r0l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6r0l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6r0l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6r0l ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r0l OCA], [https://pdbe.org/6r0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r0l RCSB], [https://www.ebi.ac.uk/pdbsum/6r0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r0l ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 07:05, 30 September 2020

2020-09-30T07:05:18Z

←Older revision		Revision as of 07:05, 30 September 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6r0l ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='6r0l' size='340' side='right'caption='[[6r0l]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6r0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r0l OCA], [http://pdbe.org/6r0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r0l RCSB], [http://www.ebi.ac.uk/pdbsum/6r0l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r0l ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 04:52, 2 September 2020

2020-09-02T04:52:12Z

←Older revision		Revision as of 04:52, 2 September 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6r0l is ON HOLD	+	The entry 6r0l is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 03:46, 5 August 2020

2020-08-05T03:46:10Z

←Older revision		Revision as of 03:46, 5 August 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6r0l is ON HOLD ~~until Paper Publication~~	+	The entry 6r0l is ON HOLD

	Authors:		Authors:

OCA at 06:01, 11 March 2020

2020-03-11T06:01:07Z

←Older revision		Revision as of 06:01, 11 March 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6r0l is ON HOLD	+	The entry 6r0l is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6r0l" [edit=sysop:move=sysop]

2019-03-20T06:15:59Z

Protected "6r0l" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:15, 20 March 2019

OCA: New page: '''Unreleased structure''' The entry 6r0l is ON HOLD Authors: Description: Category: Unreleased Structures

2019-03-20T06:15:57Z

New page: '''Unreleased structure''' The entry 6r0l is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6r0l is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]