OCA at 08:18, 20 January 2021

2021-01-20T08:18:30Z

←Older revision		Revision as of 08:18, 20 January 2021
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	==REP related 18-mer DNA==		==REP related 18-mer DNA==
-	<StructureSection load='6ror' size='340' side='right'caption='[[6ror]]' scene=''>	+	<StructureSection load='6ror' size='340' side='right'caption='[[6ror]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ROR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ROR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ror]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ROR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ROR FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ror FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ror OCA], [http://pdbe.org/6ror PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ror RCSB], [http://www.ebi.ac.uk/pdbsum/6ror PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ror ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ror FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ror OCA], [http://pdbe.org/6ror PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ror RCSB], [http://www.ebi.ac.uk/pdbsum/6ror PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ror ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Solution and crystal data are reported for DNA 18-mers with sequences related to those of bacterial noncoding single-stranded DNA segments called repetitive extragenic palindromes (REPs). Solution CD and melting data showed that the CG-rich, near-palindromic REPs from various bacterial species exhibit dynamic temperature-dependent and concentration-dependent equilibria, including architectures compatible with not only hairpins, which are expected to be biologically relevant, but also antiparallel duplexes and bimolecular tetraplexes. Three 18-mer oligonucleotides named Hpar-18 (PDB entry 6rou), Chom-18 (PDB entry 6ros) and its brominated variant Chom-18Br (PDB entry 6ror) crystallized as isomorphic right-handed A-like duplexes. The low-resolution crystal structures were solved with the help of experimental phases for Chom-18Br. The center of the duplexes is formed by two successive T-T noncanonical base pairs (mismatches). They do not deform the double-helical geometry. The presence of T-T mismatches prompted an analysis of the geometries of these and other noncanonical pairs in other DNA crystals in terms of their fit to the experimental electron densities (RSCC) and their geometric fit to the NtC (dinucleotide conformational) classes (https://dnatco.datmos.org/). Throughout this work, knowledge of the NtC classes was used to refine and validate the crystal structures, and to analyze the mismatches.
		+
		+	Structural variability of CG-rich DNA 18-mers accommodating double T-T mismatches.,Kolenko P, Svoboda J, Cerny J, Charnavets T, Schneider B Acta Crystallogr D Struct Biol. 2020 Dec 1;76(Pt 12):1233-1243. doi:, 10.1107/S2059798320014151. Epub 2020 Nov 24. PMID:33263329<ref>PMID:33263329</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6ror" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kolenko P]]	+	[[Category: Kolenko, P]]
-	[[Category: Schneider B]]	+	[[Category: Schneider, B]]
-	[[Category: Svoboda J]]	+	[[Category: Svoboda, J]]
		+	[[Category: A-dna]]
		+	[[Category: Cardiobacterium homini]]
		+	[[Category: Dna]]
		+	[[Category: Duplex]]
		+	[[Category: Non-canonical pairing]]
		+	[[Category: Rep]]
		+	[[Category: T-t mismatch]]

OCA at 14:01, 8 July 2020

2020-07-08T14:01:40Z

←Older revision		Revision as of 14:01, 8 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6ror ~~is ON HOLD~~	+	==REP related 18-mer DNA==
-		+	<StructureSection load='6ror' size='340' side='right'caption='[[6ror]]' scene=''>
-	~~Authors~~: ~~Kolenko~~, P., ~~Svoboda~~, J., ~~Schneider~~, B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ROR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ROR FirstGlance]. <br>
-	~~Description: REP related 18-mer DNA~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ror FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ror OCA], [http://pdbe.org/6ror PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ror RCSB], [http://www.ebi.ac.uk/pdbsum/6ror PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ror ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Schneider, B~~]]	+	__TOC__
-	[[Category: ~~Kolenko, P~~]]	+	</StructureSection>
-	[[Category: Svoboda, J]]	+	[[Category: Large Structures]]
		+	[[Category: Kolenko P]]
		+	[[Category: Schneider B]]
		+	[[Category: Svoboda J]]

OCA: Protected "6ror" [edit=sysop:move=sysop]

2019-05-22T04:17:10Z

Protected "6ror" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:17, 22 May 2019

OCA: New page: '''Unreleased structure''' The entry 6ror is ON HOLD Authors: Kolenko, P., Svoboda, J., Schneider, B. Description: REP related 18-mer DNA Category: Unreleased Structures [[Category...

2019-05-22T04:17:08Z

New page: '''Unreleased structure''' The entry 6ror is ON HOLD Authors: Kolenko, P., Svoboda, J., Schneider, B. Description: REP related 18-mer DNA Category: Unreleased Structures [[Category...

New page

'''Unreleased structure'''

The entry 6ror is ON HOLD

Authors: Kolenko, P., Svoboda, J., Schneider, B.

Description: REP related 18-mer DNA
[[Category: Unreleased Structures]]
[[Category: Schneider, B]]
[[Category: Kolenko, P]]
[[Category: Svoboda, J]]

6ror - Revision history

OCA at 08:18, 20 January 2021

OCA at 14:01, 8 July 2020

OCA: Protected "6ror" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6ror is ON HOLD Authors: Kolenko, P., Svoboda, J., Schneider, B. Description: REP related 18-mer DNA Category: Unreleased Structures [[Category...