6rwy - Revision history

OCA at 05:55, 11 April 2020

2020-04-11T05:55:04Z

←Older revision		Revision as of 05:55, 11 April 2020
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	<SX load='6rwy' size='340' side='right' viewer='molstar' caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>		<SX load='6rwy' size='340' side='right' viewer='molstar' caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RWY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RWY FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6rwx\|6rwx]], [[6rwk\|6rwk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6rwx\|6rwx]], [[6rwk\|6rwk]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mxiH, CP0137 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mxiH, CP0137 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwy OCA], [http://pdbe.org/6rwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwy RCSB], [http://www.ebi.ac.uk/pdbsum/6rwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwy OCA], [http://pdbe.org/6rwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwy RCSB], [http://www.ebi.ac.uk/pdbsum/6rwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 00:26, 7 March 2020

2020-03-07T00:26:17Z

←Older revision		Revision as of 00:26, 7 March 2020
Line 1:		Line 1:

	==Export apparatus core and inner rod of the Shigella type 3 secretion system==		==Export apparatus core and inner rod of the Shigella type 3 secretion system==
-	<~~StructureSection~~ load='6rwy' size='340' side='right'caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>	+	<SX load='6rwy' size='340' side='right' viewer='molstar' caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWY FirstGlance]. <br>		<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWY FirstGlance]. <br>
Line 23:		Line 23:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Shigella paradysenteriae weldin 1927]]		[[Category: Shigella paradysenteriae weldin 1927]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 07:16, 4 March 2020

2020-03-04T07:16:24Z

←Older revision		Revision as of 07:16, 4 March 2020
Line 3:		Line 3:
	<StructureSection load='6rwy' size='340' side='right'caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>		<StructureSection load='6rwy' size='340' side='right'caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWY FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6rwx\|6rwx]], [[6rwk\|6rwk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6rwx\|6rwx]], [[6rwk\|6rwk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mxiH, CP0137 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwy OCA], [http://pdbe.org/6rwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwy RCSB], [http://www.ebi.ac.uk/pdbsum/6rwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwy OCA], [http://pdbe.org/6rwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwy RCSB], [http://www.ebi.ac.uk/pdbsum/6rwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/SPAQ_SHIFL SPAQ_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the Ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/SPAP_SHIFL SPAP_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/MXIH_SHIFL MXIH_SHIFL]] Necessary for the secretion of IPA invasins. [[http://www.uniprot.org/uniprot/SPAR_SHIFL SPAR_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three ipa proteins.		[[http://www.uniprot.org/uniprot/SPAQ_SHIFL SPAQ_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the Ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/SPAP_SHIFL SPAP_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/MXIH_SHIFL MXIH_SHIFL]] Necessary for the secretion of IPA invasins. [[http://www.uniprot.org/uniprot/SPAR_SHIFL SPAR_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three ipa proteins.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Type III Secretion Systems (T3SS) needle complex is a conserved syringe-shaped protein translocation nanomachine with a mass of about 3.5 MDa essential for the survival and virulence of many Gram-negative bacterial pathogens. This system is composed of a membrane-embedded basal body and an extracellular needle that deliver effector proteins into host cells. High-resolution structures of the T3SS from different organisms and infection stages are needed to understand the underlying molecular mechanisms of effector translocation. Here, we present the cryo-electron microscopy structure of the isolated Shigella T3SS needle complex. The inner membrane (IM) region of the basal body adopts 24-fold rotational symmetry and forms a channel system that connects the bacterial periplasm with the export apparatus cage. The secretin oligomer adopts a heterogeneous architecture with 16- and 15-fold cyclic symmetry in the periplasmic N-terminal connector and C-terminal outer membrane ring, respectively. Two out of three IM subunits bind the secretin connector via a beta-sheet augmentation. The cryo-EM map also reveals the helical architecture of the export apparatus core, the inner rod, the needle and their intervening interfaces.
		+
		+	Cryo-EM structure of the Shigella type III needle complex.,Lunelli M, Kamprad A, Burger J, Mielke T, Spahn CMT, Kolbe M PLoS Pathog. 2020 Feb 24;16(2):e1008263. doi: 10.1371/journal.ppat.1008263. PMID:32092125<ref>PMID:32092125</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6rwy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Shigella paradysenteriae weldin 1927]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Shigella flexneri]]		[[Category: Shigella flexneri]]

OCA at 04:23, 13 February 2020

2020-02-13T04:23:04Z

←Older revision		Revision as of 04:23, 13 February 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6rwy is ~~ON HOLD~~	+	==Export apparatus core and inner rod of the Shigella type 3 secretion system==
-		+	<StructureSection load='6rwy' size='340' side='right'caption='[[6rwy]], [[Resolution\|resolution]] 5.11Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6rwy]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWY FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6rwx\|6rwx]], [[6rwk\|6rwk]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwy OCA], [http://pdbe.org/6rwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwy RCSB], [http://www.ebi.ac.uk/pdbsum/6rwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwy ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SPAQ_SHIFL SPAQ_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the Ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/SPAP_SHIFL SPAP_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three Ipa proteins. [[http://www.uniprot.org/uniprot/MXIH_SHIFL MXIH_SHIFL]] Necessary for the secretion of IPA invasins. [[http://www.uniprot.org/uniprot/SPAR_SHIFL SPAR_SHIFL]] Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of the three ipa proteins.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Shigella flexneri]]
		+	[[Category: Kamprad, A]]
		+	[[Category: Lunelli, M]]
		+	[[Category: Injectisome]]
		+	[[Category: Protein translocation]]
		+	[[Category: Protein transport]]
		+	[[Category: Shigella]]
		+	[[Category: Type 3 secretion system]]

OCA: Protected "6rwy" [edit=sysop:move=sysop]

2019-06-12T04:15:34Z

Protected "6rwy" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:15, 12 June 2019

OCA: New page: '''Unreleased structure''' The entry 6rwy is ON HOLD Authors: Description: Category: Unreleased Structures

2019-06-12T04:15:33Z

New page: '''Unreleased structure''' The entry 6rwy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6rwy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]