6s10 - Revision history

OCA at 11:02, 14 June 2023

2023-06-14T11:02:02Z

←Older revision		Revision as of 11:02, 14 June 2023
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	==NMR solution structure of a ProQ homolog from Legionella pneumophila==		==NMR solution structure of a ProQ homolog from Legionella pneumophila==
-	<StructureSection load='6s10' size='340' side='right'caption='[[6s10~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='6s10' size='340' side='right'caption='[[6s10]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6s10]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_33152 Atcc 33152~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S10 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6S10 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6s10]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S10 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">proQ_1, proQ_2, ERS240541_00599, NCTC12024_01603 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=446 ATCC 33152])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s10 OCA], [https://pdbe.org/6s10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s10 RCSB], [https://www.ebi.ac.uk/pdbsum/6s10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s10 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6s10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s10 OCA], [~~http~~://pdbe.org/6s10 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6s10 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6s10 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6s10 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5ZUU4_LEGPH Q5ZUU4_LEGPH]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 33152]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Hacker, C~~]]	+	[[Category: Legionella pneumophila]]
-	[[Category: ~~Immer,~~ C]]	+	[[Category: Hacker C]]
-	[[Category: ~~Woehnert, J~~]]	+	[[Category: Immer C]]
-	[[Category: ~~Proq]]~~	+	[[Category: Woehnert J]]
-	~~[[Category: Rna binding protein]]~~	+
-	~~[[Category: Srna~~]]	+

OCA at 06:11, 14 October 2020

2020-10-14T06:11:46Z

←Older revision		Revision as of 06:11, 14 October 2020
Line 1:		Line 1:

	==NMR solution structure of a ProQ homolog from Legionella pneumophila==		==NMR solution structure of a ProQ homolog from Legionella pneumophila==
-	<StructureSection load='6s10' size='340' side='right'caption='[[6s10]]' scene=''>	+	<StructureSection load='6s10' size='340' side='right'caption='[[6s10]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S10 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6S10 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6s10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33152 Atcc 33152]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S10 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6S10 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6s10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s10 OCA], [http://pdbe.org/6s10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s10 RCSB], [http://www.ebi.ac.uk/pdbsum/6s10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s10 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">proQ_1, proQ_2, ERS240541_00599, NCTC12024_01603 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=446 ATCC 33152])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6s10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s10 OCA], [http://pdbe.org/6s10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s10 RCSB], [http://www.ebi.ac.uk/pdbsum/6s10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s10 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Small regulatory RNAs (sRNAs) play an important role for posttranscriptional gene regulation in bacteria. sRNAs recognize their target messenger RNAs (mRNAs) by base pairing, which is often facilitated by interactions with the bacterial RNA-binding proteins Hfq or ProQ. The FinO/ProQ RNA-binding protein domain was first discovered in the bacterial repressor of conjugation, FinO. Since then, the functional role of FinO/ProQ-like proteins in posttranscriptional gene regulation was extensively studied in particular in the enterobacteria E. coli and Salmonella enterica and a wide range of sRNA-targets was identified for these proteins. In addition, enterobacterial ProQ homologs also recognize and protect the 3'-ends of a number of mRNAs from exonucleolytic degradation. However, the RNA-binding properties of FinO/ProQ proteins with regard to the recognition of different RNA targets are not yet fully understood. Here, we present the solution NMR structure of the so far functionally uncharacterized ProQ homolog Lpp1663 from Legionella pneumophila as a newly confirmed member and a minimal model system of the FinO/ProQ protein family. In addition, we characterize the RNA-binding preferences of Lpp1663 with high resolution NMR spectroscopy and isothermal titration calorimetry (ITC). Our results suggest a binding preference for single-stranded uridine-rich RNAs in the vicinity of stable stem-loop structures. According to chemical shift perturbation experiments, the single-stranded U-rich RNAs interact mainly with a conserved RNA-binding surface on the concave site of Lpp1663.
		+
		+	Solution structure and RNA-binding of a minimal ProQ-homolog from Legionella pneumophila (Lpp1663).,Immer C, Hacker C, Wohnert J RNA. 2020 Sep 28. pii: rna.077354.120. doi: 10.1261/rna.077354.120. PMID:32989045<ref>PMID:32989045</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6s10" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 33152]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hacker C]]	+	[[Category: Hacker, C]]
-	[[Category: Immer C]]	+	[[Category: Immer, C]]
-	[[Category: Woehnert J]]	+	[[Category: Woehnert, J]]
		+	[[Category: Proq]]
		+	[[Category: Rna binding protein]]
		+	[[Category: Srna]]

OCA at 14:03, 8 July 2020

2020-07-08T14:03:53Z

←Older revision		Revision as of 14:03, 8 July 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6s10 is ~~ON HOLD~~	+	==NMR solution structure of a ProQ homolog from Legionella pneumophila==
-		+	<StructureSection load='6s10' size='340' side='right'caption='[[6s10]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S10 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6S10 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6s10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s10 OCA], [http://pdbe.org/6s10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s10 RCSB], [http://www.ebi.ac.uk/pdbsum/6s10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s10 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hacker C]]
		+	[[Category: Immer C]]
		+	[[Category: Woehnert J]]

OCA: Protected "6s10" [edit=sysop:move=sysop]

2019-06-26T05:28:32Z

Protected "6s10" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:28, 26 June 2019

OCA: New page: '''Unreleased structure''' The entry 6s10 is ON HOLD Authors: Description: Category: Unreleased Structures

2019-06-26T05:28:30Z

New page: '''Unreleased structure''' The entry 6s10 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6s10 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]