OCA at 12:46, 24 January 2024

2024-01-24T12:46:42Z

←Older revision		Revision as of 12:46, 24 January 2024
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	==X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay==		==X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay==
-	<StructureSection load='6sro' size='340' side='right'caption='[[6sro]]' scene=''>	+	<StructureSection load='6sro' size='340' side='right'caption='[[6sro]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SRO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6SRO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6sro]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SRO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6sro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sro OCA], [~~http~~://pdbe.org/6sro PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6sro RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6sro PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6sro ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sro OCA], [https://pdbe.org/6sro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sro RCSB], [https://www.ebi.ac.uk/pdbsum/6sro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sro ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/THM1_THADA THM1_THADA] Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	X-ray free-electron lasers (XFELs) enable crystallographic structure determination beyond the limitations imposed upon synchrotron measurements by radiation damage. The need for very short XFEL pulses is relieved through gating of Bragg diffraction by loss of crystalline order as damage progresses, but not if ionization events are spatially non-uniform due to underlying elemental distributions, as in biological samples. Indeed, correlated movements of iron and sulfur ions were observed in XFEL-irradiated ferredoxin microcrystals using unusually long pulses of 80 fs. Here, we report a femtosecond time-resolved X-ray pump/X-ray probe experiment on protein nanocrystals. We observe changes in the protein backbone and aromatic residues as well as disulfide bridges. Simulations show that the latter's correlated structural dynamics are much slower than expected for the predicted high atomic charge states due to significant impact of ion caging and plasma electron screening. This indicates that dense-environment effects can strongly affect local radiation damage-induced structural dynamics.
		+
		+	Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses.,Nass K, Gorel A, Abdullah MM, V Martin A, Kloos M, Marinelli A, Aquila A, Barends TRM, Decker FJ, Bruce Doak R, Foucar L, Hartmann E, Hilpert M, Hunter MS, Jurek Z, Koglin JE, Kozlov A, Lutman AA, Kovacs GN, Roome CM, Shoeman RL, Santra R, Quiney HM, Ziaja B, Boutet S, Schlichting I Nat Commun. 2020 Apr 14;11(1):1814. doi: 10.1038/s41467-020-15610-4. PMID:32286284<ref>PMID:32286284</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6sro" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Thaumatococcus daniellii]]
	[[Category: Gorel A]]		[[Category: Gorel A]]
	[[Category: Kloos M]]		[[Category: Kloos M]]
	[[Category: Nass K]]		[[Category: Nass K]]

OCA at 05:43, 22 April 2020

2020-04-22T05:43:56Z

←Older revision		Revision as of 05:43, 22 April 2020
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-	'''Unreleased structure'''

-	~~The entry 6sro is ON HOLD~~	+	==X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay==
-		+	<StructureSection load='6sro' size='340' side='right'caption='[[6sro]]' scene=''>
-	~~Authors: Kloos, M., Gorel, A., Nass, K.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SRO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6SRO FirstGlance]. <br>
-	~~Description:~~ X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6sro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sro OCA], [http://pdbe.org/6sro PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sro RCSB], [http://www.ebi.ac.uk/pdbsum/6sro PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sro ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Gorel, A]]	+	__TOC__
-	[[Category: ~~Nass, K~~]]	+	</StructureSection>
-	[[Category: ~~Kloos, M~~]]	+	[[Category: Large Structures]]
		+	[[Category: Gorel A]]
		+	[[Category: Kloos M]]
		+	[[Category: Nass K]]

OCA: Protected "6sro" [edit=sysop:move=sysop]

2019-10-02T07:39:27Z

Protected "6sro" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:39, 2 October 2019

OCA: New page: '''Unreleased structure''' The entry 6sro is ON HOLD Authors: Kloos, M., Gorel, A., Nass, K. Description: X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay [[Category:...

2019-10-02T07:39:25Z

New page: '''Unreleased structure''' The entry 6sro is ON HOLD Authors: Kloos, M., Gorel, A., Nass, K. Description: X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay [[Category:...

New page

'''Unreleased structure'''

The entry 6sro is ON HOLD

Authors: Kloos, M., Gorel, A., Nass, K.

Description: X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay
[[Category: Unreleased Structures]]
[[Category: Gorel, A]]
[[Category: Nass, K]]
[[Category: Kloos, M]]

6sro - Revision history

OCA at 12:46, 24 January 2024

OCA at 05:43, 22 April 2020

OCA: Protected "6sro" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6sro is ON HOLD Authors: Kloos, M., Gorel, A., Nass, K. Description: X-ray pump X-ray probe on thaumatin nanocrystals: 76 fs time delay [[Category:...